Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sonisha Warren"'
Autor:
David Tran, Dongjiang Chen, Sonisha Warren, Tarun E. Hutchinson, Mathew Sebastian, Dan Jin, Ashley Ghiaseddin, Son Le, Annie Allen
Publikováno v:
Neuro Oncol
OBJECTIVES Tumor Treating Fields (TTFields) was approved in combination with adjuvant temozolomide chemotherapy for newly diagnosed Glioblastoma (GBM) patients and resulted in a significant improvement in overall survival. TTFields are low-intensity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfa1ff2f7d2dbf1ed4968066a736525
https://europepmc.org/articles/PMC7651242/
https://europepmc.org/articles/PMC7651242/
Autor:
Sonisha Warren, Deborah Sampson, Maryam Rahman, Dongjiang Chen, Ashley Ghiaseddin, David Tran, Anne Allen, Valerie Greene, Nagheme Thomas
Publikováno v:
Neuro Oncol
BACKGROUND/OBJECTIVE Tumor treating Fields (TTFields) plus maintenance temozolomide is an approved standard treatment for newly diagnosed Glioblastoma (GBM). TTFields are alternating electric fields of low intensity and intermediate frequency deliver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ee9064367974e58655b2a2067df1c0
https://europepmc.org/articles/PMC6847508/
https://europepmc.org/articles/PMC6847508/
Autor:
Glenn A. Walter, Hideko Kasahara, Sonisha Warren, Stephen M. Chrzanowski, Robert H. Anderson, Byung-Ho Kang, Hassan Ashraf, Jeena Kar, Michael T. Massengill, Huadong Zeng, Richard L. Moss, Rajib Chowdhury
Publikováno v:
Cardiovascular Research. 111:34-43
Aims Under pressure overload, initial adaptive hypertrophy of the heart is followed by cardiomyocyte elongation, reduced contractile force, and failure. The mechanisms governing the transition to failure are not fully understood. Pressure overload re
Autor:
Valerie Greene, Maryam Rahman, Sonisha Warren, Ashley Ghiaseddin, Dongjiang Chen, Alexandra Sherman, Deborah Sampson, Annie Allen, David Tran
Publikováno v:
Neuro Oncol
INTRODUCTION Tumor-treating fields (TTFields) are a new standard anti-mitotic treatment for newly diagnosed glioblastoma (ndGBM). Emerging data indicate that TTFields also stimulate innate immunity, leading to adaptive immunity. We hypothesize that i
Autor:
Valerie Greene, Gregory J. A. Murad, Sonisha Warren, William A. Friedman, Maryam Rahman, Anthony T. Yachnis, David Tran, Ashley Ghiaseddin, Steven N. Roper, Anne Allen
Prognosis of relapsed glioblastoma (GBM) is dismal and current treatment fails to provide prolonged survival. Small subsets of patients respond well to some novel therapeutics probably due to the genetic variations of tumors and patients. In the Phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a464b062c92858feabd6a4d7bfcc99
https://europepmc.org/articles/PMC6216658/
https://europepmc.org/articles/PMC6216658/
Autor:
Hassan Ashraf, Mini Manchanda, Apoorva Mohan, Konstantinos Charizanis, Christopher M. Chamberlain, Ranjan Batra, Moyi Li, Hannah Hong, Dustin J. Finn, Maurice S. Swanson, Kuang-Yung Lee, Laura P.W. Ranum, Hideko Kasahara, Sonisha Warren
Publikováno v:
EMBO Molecular Medicine
Myotonic dystrophy (DM) is a multi‐systemic disease that impacts cardiac and skeletal muscle as well as the central nervous system (CNS). DM is unusual because it is an RNA‐mediated disorder due to the expression of toxic microsatellite expansion
Autor:
Thomas P. Yang, Wei-Ming Chien, Tsugio Seki, Ryota Terada, Michael T. Chin, Ellen O. Weinberg, Jörg Bungert, Laura E Briggs, Hideko Kasahara, Sonisha Warren, Colleen T. Cole-Jeffrey
Publikováno v:
Molecular and Cellular Biology. 31:4633-4645
Atrial natriuretic factor (ANF) is abundantly expressed in atrial cardiomyocytes throughout ontogeny and in ventricular cardiomyocytes in the developing heart. However, during cardiac failure and hypertrophy, ANF expression can reappear in adult vent
Autor:
Kenneth R. Chien, Hideko Kasahara, Jonathan T. Lu, Andy Wessels, Sonisha Warren, Ryota Terada
Publikováno v:
Cardiovascular Research. 91:289-299
Aims Human congenital heart disease linked to mutations in the homeobox transcription factor, NKX2-5, is characterized by cardiac anomalies, including atrial and ventricular septal defects as well as conduction and occasional defects in contractility
Autor:
Anne Allen, Jian Campian, Valerie Greene, Sonisha Warren, Ashley Ghiaseddin, David Tran, Deborah Sampson, George Ansstas, Stephen Staal
Publikováno v:
Neuro-Oncology. 20:vi1-vi1
Despite aggressive treatment with surgery, radiation therapy and chemotherapy, the median overall survival for recurrent glioblastoma (rGBM) averages 25 weeks. Our prior experience in 8 bevacizumab-refractory GBM patients initially treated with TTFie
Autor:
Sonisha Warren, Kenneth R. Chien, Jonathan T. Lu, Hiroko Wakimoto, Hideko Kasahara, Melissa H Marks, Keith D. Robertson, Laura E Briggs, Morihiko Takeda, Ellen O. Weinberg
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Mutations in homeoprotein NKX2-5 are linked to human congenital heart disease, resulting in various cardiac anomalies, as well as in postnatal progressive conduction defects and occasional left ventricular dysfunction; yet the function of Nkx2-5 in t