Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Sonia Y Khan"'
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Akademický článek
Cryoablation of primary breast cancer tumors induces a systemic abscopal effect altering TIME (Tumor Immune Microenvironment) in distant tumors
Autor: Flávia Sardela de Miranda, Dalia Martinez-Marin, Rachel L. Babcock, Maribel Castro, Geetha P. Boligala, Sonia Y. Khan, Kathryn L. Furr, Isabel Castro-Piedras, Nicholas Wagner, Dakota E. Robison, Karla Daniele, Sharda P. Singh, Kevin Pruitt, Michael W. Melkus, Rakhshanda Layeequr Rahman
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
IntroductionDespite recent advances, triple-negative breast cancer (TNBC) patients remain at high risk for recurrence and metastasis, which creates the need for innovative therapeutic approaches to improve patient outcomes. Cryoablation is a promisin
Externí odkaz: https://doaj.org/article/96a7604dd36f4009ad8d924e431a7be9
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2
Akademický článek
Dishevelled 2 regulates cancer cell proliferation and T cell mediated immunity in HER2-positive breast cancer
Autor: Fahmida Rasha, Geetha Priya Boligala, Mingxiao V. Yang, Dalia Martinez-Marin, Isabel Castro-Piedras, Kathryn Furr, Annie Snitman, Sonia Y. Khan, Luis Brandi, Maribel Castro, Hafiz Khan, Nusrat Jahan, Sharilyn Almodovar, Michael W. Melkus, Kevin Pruitt, Rakhshanda Layeequr Rahman
Publikováno v: BMC Cancer, Vol 23, Iss 1, Pp 1-18 (2023)
Abstract Background Dishevelled paralogs (DVL1, 2, 3) are key mediators of Wnt pathway playing a role in constitutive oncogenic signaling influencing the tumor microenvironment. While previous studies showed correlation of β-catenin with T cell gene
Externí odkaz: https://doaj.org/article/8ea1b3462046437d99d48335c2b3d3bc
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3
Abstract P5-10-04: Exploring novel connections between dishevelled (DVL) proteins and HER2-positive breast cancer-road to translation
Autor: Fahmida Rasha, Mingxiao V Yang, Isabel Castro-Piedras, Kathryn L. Furr, Annie Snitman, Sonia Y. Khan, Luis Brandi, Hafiz Khan, Nusrat Jahan, Michael W. Melkus, Kevin Pruitt, Rakhshanda Layeequr Rahman
Publikováno v: Cancer Research. 82:P5-10
Aberrant Wnt signaling contributes to every stage of tumorigenesis from immunosuppression in the tumor microenvironment (TME) and reduced tumor infiltrating lymphocytes (TIL) activity in the tumor niche to modulating several cancer hallmarks such as
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b7fb1f45724d2250f6f294ab6d54169
https://doi.org/10.1158/1538-7445.sabcs21-p5-10-04
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10
Abstract B18: Breast cancer cryoablation in combination with anti-CTLA-4 increases T cell activation in a murine tumor model
Autor: Flavia Sardela de Miranda, Rachel Babcock, Maribel Castro, Sonia Y Khan, Carsen Roach, Thomas Hintelmann, Kathryn Furr, Chang H Lee, Geetha P Boligala, Fahmida Rasha, Luis Brandi, Harvinder S Gill, Kevin Pruitt, Rakhshanda L Rahman
Publikováno v: Cancer Immunology Research. 10:B18-B18
Introduction: Triple-negative and HER2+ breast cancers (BCs) are high-risk subtypes that spread easily and are hard to treat. Thus, newer therapeutic approaches that can prevent local recurrence and metastatic spread of disease are required. Cryoabla
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3a3a1ecf9f3d2420447c6d4a3aa79f6
https://doi.org/10.1158/2326-6074.tumimm22-b18
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