Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sonia Wulf"'
Autor:
Larissa Seifert, Gunther Zahner, Catherine Meyer-Schwesinger, Naemi Hickstein, Silke Dehde, Sonia Wulf, Sarah M. S. Köllner, Renke Lucas, Dominik Kylies, Sarah Froembling, Stephanie Zielinski, Oliver Kretz, Anna Borodovsky, Sergey Biniaminov, Yanyan Wang, Hong Cheng, Friedrich Koch-Nolte, Peter F. Zipfel, Helmut Hopfer, Victor G. Puelles, Ulf Panzer, Tobias B. Huber, Thorsten Wiech, Nicola M. Tomas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
It is generally thought that complement activation in human membranous nephropathy (MN) occurs predominantly via the lectin or alternative pathway. Here, the authors show that the classical pathway is the dominant form of complement activation in MN
Externí odkaz:
https://doaj.org/article/c71d3e45f83243fc953b6a19b9d58113
Autor:
Sarah Irmscher, Svante L. H. Zipfel, Luke D. Halder, Lia Ivanov, Andres Gonzalez-Delgado, Christoph Waldeyer, Moritz Seiffert, Fabian J. Brunner, Monika von der Heide, Ina Löschmann, Sonia Wulf, Darina Czamara, Nikolina Papac-Milicevic, Olaf Strauß, Stefan Lorkowski, Hermann Reichenspurner, Michael V. Holers, Nirmal K. Banda, Tania Zeller, Elisabeth B. Binder, Christoph J. Binder, Thorsten Wiech, Peter F. Zipfel, Christine Skerka
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Atherosclerotic cardiovascular disease (ACVD) is a lipid-driven inflammatory disease and one of the leading causes of death worldwide. Lipid deposits in the arterial wall lead to the formation of plaques that involve lipid oxidation, cellula
Externí odkaz:
https://doaj.org/article/f4fef222f3624b56b6f873bb7fc7bb7a
Autor:
Tilman Schmidt, Sara Afonso, Luce Perie, Karin Heidenreich, Sonia Wulf, Christian F. Krebs, Peter F. Zipfel, Thorsten Wiech
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Since the re-classification of membranoproliferative glomerulonephritis the new disease entity C3 glomerulopathy is diagnosed if C3 deposition is clearly dominant over immunoglobulins in immunohistochemistry or immunofluorescence. Although this new d
Externí odkaz:
https://doaj.org/article/790b4967f01b4ebab91eca8d0437d45e
Autor:
Sarah Irmscher, Silke R. Brix, Svante L. H. Zipfel, Luke D. Halder, Sibel Mutlutürk, Sonia Wulf, Evaldas Girdauskas, Hermann Reichenspurner, Rolf A. K. Stahl, Berit Jungnickel, Thorsten Wiech, Peter F. Zipfel, Christine Skerka
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
FHR1 is a serum protein implicated in complement regulation. Here the authors show that human FHR1 binds to necrotic cells, triggering inflammasome activation in monocytes in culture, localizes to necrotic tissue and correlates with inflammatory cyto
Externí odkaz:
https://doaj.org/article/37aad357dc58436e9dd86d7bd2bd62bb
Autor:
Marina Zimmermann, Martin Klaus, Milagros N. Wong, Ann-Katrin Thebille, Lukas Gernhold, Christoph Kuppe, Maurice Halder, Jennifer Kranz, Nicola Wanner, Fabian Braun, Sonia Wulf, Thorsten Wiech, Ulf Panzer, Christian F. Krebs, Elion Hoxha, Rafael Kramann, Tobias B. Huber, Stefan Bonn, Victor G. Puelles
Publikováno v:
JCI Insight, Vol 6, Iss 7 (2021)
Morphologic examination of tissue biopsies is essential for histopathological diagnosis. However, accurate and scalable cellular quantification in human samples remains challenging. Here, we present a deep learning–based approach for antigen-specif
Externí odkaz:
https://doaj.org/article/3c08e835153e4f5397578a86dbdc44f5
Autor:
Thorsten Wiech, Linda Reinhard, Sonia Wulf, Alfio Edoardo Giuffrida, Elisa Longhitano, Rosario Caruso, Hermann-Josef Gröne, Rolf A K Stahl, Peter F Zipfel, Judith Kikhney, Annette Moter, Elion Hoxha, Domenico Santoro
Publikováno v:
Lancet (London, England). 400(10366)
Autor:
Sonia Wulf, Christine Skerka, Jun Oh, Wilfrid Fehrle, Tim Petschull, Sergey Biniaminov, Peter F. Zipfel, Thorsten Wiech, Fermin Person, Franziska Buescheck
Publikováno v:
Kidney International Reports
Autor:
Rolf A.K. Stahl, Hermann Reichenspurner, Evaldas Girdauskas, Silke R. Brix, Thorsten Wiech, Sibel Mutlutürk, Luke D. Halder, Sonia Wulf, S. Zipfel, Christine Skerka, Berit Jungnickel, Peter F. Zipfel, Sarah Irmscher
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Persistent inflammation is a hallmark of many human diseases, including anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) and atherosclerosis. Here, we describe a dominant trigger of inflammation: human serum factor H-related protein F
Autor:
Victor G. Puelles, Martin Klaus, Jennifer Kranz, Nicola Wanner, Milagros N. Wong, Marina Zimmermann, Christoph Kuppe, Elion Hoxha, Christian Krebs, Ann-Katrin Thebille, Ulf Panzer, Stefan Bonn, Thorsten Wiech, Fabian Braun, Rafael Kramann, Maurice Halder, Lukas Gernhold, Sonia Wulf, Tobias B. Huber
Morphologic examination of tissue biopsies is essential for histopathological diagnosis. However, accurate and scalable cellular quantification in human samples remains challenging. Here, we present a deep learning-based approach for antigen-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f45ffd845636ac2e5993bb182da90407
https://doi.org/10.1101/2020.08.23.263392
https://doi.org/10.1101/2020.08.23.263392
Autor:
Sebastian Lunemann, Emma Kraus, Tobias B. Huber, Tobias Koyro, Florian Henseling, Adam Grundhoff, Christian Körner, Pia Fittje, Thorsten Wiech, Johannes Jung, Nicole Fischer, Sonia Wulf, Ulf Panzer, Marcus Altfeld, Angelique Hölzemer
Publikováno v:
Kidney international. 99(5)
BK polyomavirus-associated nephropathy is a common complication after kidney transplantation leading to reduced graft function or loss. The molecular pathogenesis of BK polyomavirus-induced nephropathy is not well understood. A recent study had descr