Výsledky vyhledávání - "Sonia T. Wennier"

Akademický článek

Synergistic cancer immunotherapy combines MVA-CD40L induced innate and adaptive immunity with tumor targeting antibodies

Autor: José Medina-Echeverz, Maria Hinterberger, Marco Testori, Marlene Geiger, Raphael Giessel, Barbara Bathke, Ronny Kassub, Fabienne Gräbnitz, Giovanna Fiore, Sonia T. Wennier, Paul Chaplin, Mark Suter, Hubertus Hochrein, Henning Lauterbach

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)

CD40 agonists have been investigated as a strategy to awaken the immune system against cancers. Here, the authors use a virus encoding CD40L and tumour-associated antigens to enhance innate and adaptive immunity that together with tumour targeting an

Externí odkaz: https://doaj.org/article/d593337aeba54d49978178381a7a20e5

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Akademický článek

A novel naturally occurring tandem promoter in modified vaccinia virus ankara drives very early gene expression and potent immune responses.

Autor: Sonia T Wennier, Kay Brinkmann, Charlotte Steinhäußer, Nicole Mayländer, Claudia Mnich, Ursula Wielert, Ulrike Dirmeier, Jürgen Hausmann, Paul Chaplin, Robin Steigerwald

Publikováno v: PLoS ONE, Vol 8, Iss 8, p e73511 (2013)

Modified vaccinia virus Ankara (MVA) has been shown to be suitable for the generation of experimental vaccines against cancer and infectious diseases, eliciting strong humoral and cellular immune responses. In viral vectored vaccines, strong recombin

Externí odkaz: https://doaj.org/article/cf95b989bf854404a65a1147389663d5

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P04.02 A novel cancer immunotherapy combines rMVA-CD40L with tumor targeting antibodies

Autor: Giovanna Fiore, M. Geiger, Paul Chaplin, Barbara Bathke, F Gräbnitz, Henning Lauterbach, Hubertus Hochrein, R. Kassub, José Medina-Echeverz, Raphael Giessel, Mark Suter, Sonia T. Wennier, M. Testori, Maria Hinterberger

Publikováno v: E-Poster Presentations.

Background Virus-based vaccines and appropriate costimulation potently enhance antigen-specific T cell immunity against cancer. In the present study, we exploit both innate and adaptive immune responses triggered by a novel recombinant modified vacci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::42fa61740e226e5833b67a639a30a996
https://doi.org/10.1136/jitc-2020-itoc7.71

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Synergistic cancer immunotherapy combines MVA-CD40L induced innate and adaptive immunity with tumor targeting antibodies

Autor: Fabienne Gräbnitz, Ronny Kassub, Barbara Bathke, Sonia T. Wennier, Paul Chaplin, Jose Medina-Echeverz, Marco Testori, Raphael Giessel, Marlene Geiger, Hubertus Hochrein, Henning Lauterbach, Mark Suter, Maria Hinterberger, Giovanna Fiore

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications

Virus-based vaccines and appropriate costimulation potently enhance antigen-specific T cell immunity against cancer. Here we report the use of recombinant modified vaccinia virus Ankara (rMVA) encoding costimulatory CD40L against solid tumors. Therap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206aaa221679ce742d6e0a13a6ce92ad
https://doi.org/10.1038/s41467-019-12998-6

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Intratumoral virotherapy with 4-1BBL armed modified vaccinia Ankara eradicates solid tumors and promotes protective immune memory

Autor: Henning Lauterbach, Hubertus Hochrein, José Medina-Echeverz, Ignacio Melero, Maria Hinterberger, Paul Chaplin, Raphael Giessel, Fabienne Graebnitz, Pedro Berraondo, Giovanna Fiore, Sonia T. Wennier, Barbara Bathke, Mark Suter

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)

BackgroundHuman cancers are extraordinarily heterogeneous in terms of tumor antigen expression, immune infiltration and composition. A common feature, however, is the host′s inability to mount potent immune responses that prevent tumor growth effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf13b291f8dd4bef003b572ba5d1d341
https://doi.org/10.1136/jitc-2020-001586

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Aromatic Amino Acids in the Juxtamembrane Domain of Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Are Important for Receptor-Dependent Virus Entry and Cell-Cell Fusion

Autor: Sonia T. Wennier, Emily A. Travanty, Megan W. Howard, Kathryn V. Holmes, Scott A. Jeffers, Max Smith, Larissa B. Thackray

Publikováno v: Journal of Virology

The severe acute respiratory syndrome coronavirus (SARS-CoV) spike glycoprotein (S) is a class I viral fusion protein that binds to its receptor glycoprotein, human angiotensin converting enzyme 2 (hACE2), and mediates virus entry and cell-cell fusio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f54d55c637bdae8fa75f8dcff71363
https://doi.org/10.1128/jvi.01805-07

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A novel naturally occurring tandem promoter in modified vaccinia virus ankara drives very early gene expression and potent immune responses

Autor: Robin Steigerwald, Nicole Mayländer, Paul Chaplin, Ursula Wielert, Jürgen Hausmann, Sonia T. Wennier, Ulrike Dirmeier, Claudia Mnich, Charlotte Steinhäußer, Kay Brinkmann

Publikováno v: PLoS ONE, Vol 8, Iss 8, p e73511 (2013)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a0b4b611fc2c3220d9e2007ec63bdf
http://europepmc.org/articles/PMC3741161?pdf=render

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