Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sonia Sudiwala"'
Autor:
Kit-Yi Leung, Yun Jin Pai, Qiuying Chen, Chloe Santos, Enrica Calvani, Sonia Sudiwala, Dawn Savery, Markus Ralser, Steven S. Gross, Andrew J. Copp, Nicholas D.E. Greene
Publikováno v:
Cell Reports, Vol 21, Iss 7, Pp 1795-1808 (2017)
Summary: Abnormal folate one-carbon metabolism (FOCM) is implicated in neural tube defects (NTDs), severe malformations of the nervous system. MTHFR mediates unidirectional transfer of methyl groups from the folate cycle to the methionine cycle and,
Externí odkaz:
https://doaj.org/article/abf6f1dd135c4b04b5be5c03e75400aa
Autor:
Sonia Sudiwala, Alexandra Palmer, Valentina Massa, Alan J. Burns, Louisa P. E. Dunlevy, Sandra C. P. de Castro, Dawn Savery, Kit-Yi Leung, Andrew J. Copp, Nicholas D. E. Greene
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 11 (2019)
Neural tube defects (NTDs), including spina bifida and anencephaly, are among the most common birth defects worldwide, but their underlying genetic and cellular causes are not well understood. Some NTDs are preventable by supplemental folic acid. How
Externí odkaz:
https://doaj.org/article/5ea44426f8104b8dacbf5a7faf4dee8b
Autor:
Jianlong Li, Sonia Sudiwala, Lionel Berthoin, Seayar Mohabbat, Eliza A. Gaylord, Hanan Sinada, Noel Cruz Pacheco, Jiun Chiun Chang, Oju Jeon, Isabelle M.A. Lombaert, Alison J. May, Eben Alsberg, Chelsea S. Bahney, Sarah M. Knox
Publikováno v:
Science advances, vol 8, iss 51
Salivary gland acinar cells are severely depleted after radiotherapy for head and neck cancer, leading to loss of saliva and extensive oro-digestive complications. With no regenerative therapies available, organ dysfunction is irreversible. Here, usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b482572e7c80de353c930c5a8f8e6d9
https://escholarship.org/uc/item/04h7k3s7
https://escholarship.org/uc/item/04h7k3s7
Autor:
Alison J. May, Aaron J. Mattingly, Eliza A. Gaylord, Nathan Griffin, Sonia Sudiwala, Noel Cruz-Pacheco, Elaine Emmerson, Seayar Mohabbat, Sara Nathan, Hanan Sinada, Isabelle M.A. Lombaert, Sarah M. Knox
Publikováno v:
May, A J, Mattingly, A J, Gaylord, E A, Griffin, N, Sudiwala, S, Cruz-Pacheco, N, Emmerson, E, Mohabbat, S, Nathan, S, Sinada, H, Lombaert, I & Knox, S M 2022, ' Neuronal-epithelial cross-talk drives acinar specification via NRG1-ERBB3-mTORC2 signaling ', Developmental Cell, vol. 57, no. 22, pp. 2550-2565.e5 . https://doi.org/10.1016/j.devcel.2022.10.011
Acinar cells are the principal secretory units of multiple exocrine organs. A single-cell, layered, lumenized acinus forms from a large cohort of epithelial progenitors that must initiate and coordinate three cellular programs of acinar specification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3218b114ab6b7307b65f96a6a14d4e60
https://pubmed.ncbi.nlm.nih.gov/36413949
https://pubmed.ncbi.nlm.nih.gov/36413949
Autor:
Alison J. May, Aaron J. Mattingly, Eliza A. Gaylord, Noel Cruz-Pacheco, Elaine Emmerson, Sonia Sudiwala, Seayar Mohabbat, Sara Nathan, Hanan Sinada, I Lombaert, Sarah M. Knox
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bde1c316982967bdf5bbb3635a175c9
https://doi.org/10.2139/ssrn.4090930
https://doi.org/10.2139/ssrn.4090930
Autor:
Alan J. Burns, Sonia Sudiwala, Alexandra Palmer, Kit-Yi Leung, Sandra C. P. De Castro, Andrew J. Copp, Valentina Massa, Dawn Savery, Louisa P. E. Dunlevy, Nicholas D. E. Greene
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 11 (2019)
Disease Models & Mechanisms
Disease Models & Mechanisms
Neural tube defects (NTDs), including spina bifida and anencephaly, are among the most common birth defects worldwide, but their underlying genetic and cellular causes are not well understood. Some NTDs are preventable by supplemental folic acid. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87d86160ba6fb845ea4de4e07b0e40b
http://dmm.biologists.org/content/12/11/dmm042234
http://dmm.biologists.org/content/12/11/dmm042234
Autor:
Sarah M. Knox, Sonia Sudiwala
Publikováno v:
Genesis
Genesis (New York, N.Y. : 2000), vol 57, iss 1
Genesis (New York, N.Y. : 2000), vol 57, iss 1
Organs and structures of the vertebrate head perform a plethora of tasks including visualization, digestion, vocalization/communication, auditory functions, and respiration in response to neuronal input. This input is primarily derived from afferent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9734da9e9b2d789873ce02cad307229d
https://doi.org/10.1002/dvg.23282
https://doi.org/10.1002/dvg.23282
Autor:
Timothy A, Scott, Leonor M, Quintaneiro, Povilas, Norvaisas, Prudence P, Lui, Matthew P, Wilson, Kit-Yi, Leung, Lucia, Herrera-Dominguez, Sonia, Sudiwala, Alberto, Pessia, Peter T, Clayton, Kevin, Bryson, Vidya, Velagapudi, Philippa B, Mills, Athanasios, Typas, Nicholas D E, Greene, Filipe, Cabreiro
Publikováno v:
Cell
Summary Fluoropyrimidines are the first-line treatment for colorectal cancer, but their efficacy is highly variable between patients. We queried whether gut microbes, a known source of inter-individual variability, impacted drug efficacy. Combining t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d2dc8a3b6eba239535c64036cde2bef
https://pubmed.ncbi.nlm.nih.gov/28431245
https://pubmed.ncbi.nlm.nih.gov/28431245
Autor:
Sonia, Sudiwala, Sandra C P, De Castro, Kit-Yi, Leung, John T, Brosnan, Margaret E, Brosnan, Kevin, Mills, Andrew J, Copp, Nicholas D E, Greene
Publikováno v:
Biochimie
The curly tail mouse provides a model for neural tube defects (spina bifida and exencephaly) that are resistant to prevention by folic acid. The major ct gene, responsible for spina bifida, corresponds to a hypomorphic allele of grainyhead-like 3 (Gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f79d62d17e5a57c42221b48c9478169e
https://pubmed.ncbi.nlm.nih.gov/26924399
https://pubmed.ncbi.nlm.nih.gov/26924399