Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sonia Spitzer"'
Publikováno v:
Stem Cell Reports, Vol 9, Iss 4, Pp 1262-1274 (2017)
Rat embryonic stem cells (ESCs) offer the potential for sophisticated genome engineering in this valuable biomedical model species. However, germline transmission has been rare following conventional homologous recombination and clonal selection. Her
Externí odkaz:
https://doaj.org/article/90a871ed45ea47fc8f1d5f908d6685e7
Autor:
Sonia Spitzer, David M. Bannerman, Andrzej Tkacz, Matthew Cooper, Edward O. Mann, Daniel C. Anthony, Philip W.J. Burnet, Natasa Giallourou, Philip S. Poole, Helene M. Savignac, Jonathan R. Swann
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103113-(2021)
iScience
iScience
Summary We have shown previously that prebiotic (Bimuno galacto-oligosacharides, B-GOS®) administration to neonatal rats increased hippocampal NMDAR proteins. The present study has investigated the effects of postnatal B-GOS® supplementation on hip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea821f9863b26fcf0b4cbbf208effe41
http://www.sciencedirect.com/science/article/pii/S2589004221010816
http://www.sciencedirect.com/science/article/pii/S2589004221010816
Autor:
Edward O. Mann, Jonathan R. Swann, Sonia Spitzer, David M. Bannerman, Philip W.J. Burnet, Natasa Giallourou, Andrzej Tkacz, Matthew Cooper, Philip S. Poole, Helene Savignac, Daniel C. Anthony
Publikováno v:
SSRN Electronic Journal.
Feeding neonatal rats with a prebiotic (Bimuno galacto-oligosaccharides, B-GOS®), increased hippocampal NMDAR proteins. Here, we tested the effects of postnatal B-GOS® supplementation on anxious behavior, hippocampal electrophysiology, metabolomics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3bfcb9c140f9116e93fdde3b1e8acdd
https://doi.org/10.2139/ssrn.3836128
https://doi.org/10.2139/ssrn.3836128
Autor:
Sven P. Wichert, Nicolas Renier, Julia M. Edgar, Marc Tessier-Lavigne, Klaus-Armin Nave, Georg L. Wieser, Khalad Karram, Bettina Weege, Moritz J. Rossner, Kuo Yan, Ragnhildur Thóra Káradóttir, Alexander Pieper, Amit Agarwal, Sandra Goebbels, Sonia Spitzer, Oleksandr Yagensky
The molecular trigger of CNS myelination is unknown. By targeting Pten in cerebellar granule cells and activating the AKT1–mTOR pathway, we increased the caliber of normally unmyelinated axons and the expression of numerous genes encoding regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316358f58e5541deb8df73c79b0e8532
https://eprints.gla.ac.uk/130768/13/130768.pdf
https://eprints.gla.ac.uk/130768/13/130768.pdf
Autor:
Sonia Spitzer, Anna Falk, Monte A. Gates, Ferdinando Rossi, Austin Smith, Ketty Leto, Raja Kittappa, Ole Paulsen, Ragnhildur Thóra Káradóttir, Melodie Borel, Jignesh Tailor
Publikováno v:
Journal of Neuroscience; Vol 33
Stem cell lines that faithfully maintain the regional identity and developmental potency of progenitors in the human brain would create new opportunities in developmental neurobiology and provide a resource for generating specialized human neurons. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e11948c07b685103a4a4197367e4947
Myelin is essential for the mammalian brain to function efficiently. Whilst many factors have been associated with regulating the differentiation of oligodendroglia and myelination, glutamate signalling might be particularly important for learning-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d038829db6d05071ceecb08f9cf2ed
https://www.repository.cam.ac.uk/handle/1810/256741
https://www.repository.cam.ac.uk/handle/1810/256741
Autor:
Sandra, Goebbels, Georg L, Wieser, Alexander, Pieper, Sonia, Spitzer, Bettina, Weege, Kuo, Yan, Julia M, Edgar, Oleksandr, Yagensky, Sven P, Wichert, Amit, Agarwal, Khalad, Karram, Nicolas, Renier, Marc, Tessier-Lavigne, Moritz J, Rossner, Ragnhildur Thóra, Káradóttir, Klaus-Armin, Nave
Publikováno v:
Nature neuroscience. 20(1)
The molecular trigger of CNS myelination is unknown. By targeting Pten in cerebellar granule cells and activating the AKT1-mTOR pathway, we increased the caliber of normally unmyelinated axons and the expression of numerous genes encoding regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::015682c499f1cc7de5955637fc6c4df2
https://pubmed.ncbi.nlm.nih.gov/27775720
https://pubmed.ncbi.nlm.nih.gov/27775720
Autor:
Siddharthan Chandran, Robin J.M. Franklin, Ragnhildur Thóra Káradóttir, Alastair Compston, Sybil R.L. Stacpoole, Sonia Spitzer, Bilada Bilican
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 85:e4.56-e4
We have established an efficient system to specify NG2/PDGF-Rα/OLIG2+ oligodendrocyte precursor cells (OPCs) from human embryonic stem cells (hESCs) at low, physiological (3%) oxygen levels. This was achieved via both forebrain and spinal cord origi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca09b598d8212c1554af2dba79196136
https://doi.org/10.1136/jnnp-2014-309236.149
https://doi.org/10.1136/jnnp-2014-309236.149
Publikováno v:
Stem Cell Research & Therapy
Human astrocytes are larger and more complex than those of infraprimate mammals, suggesting that their role in neural processing has expanded with evolution. To assess the cell-autonomous and species-selective properties of human glia, we engrafted h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f60cef87e013ed493db79fb9bb71184c
http://europepmc.org/articles/PMC3854849
http://europepmc.org/articles/PMC3854849