Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sonia Spinello"'
Autor:
Samanta Mazzetti, Mara De Leonardis, Gloria Gagliardi, Alessandra Maria Calogero, Milo Jarno Basellini, Laura Madaschi, Ilaria Costa, Francesca Cacciatore, Sonia Spinello, Manuela Bramerio, Roberto Cilia, Chiara Rolando, Giorgio Giaccone, Gianni Pezzoli, Graziella Cappelletti
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
HDAC6 is a unique histone deacetylase that targets cytoplasmic non-histone proteins and has a specific ubiquitin-binding activity. Both of these activities are required for HDAC6-mediated formation of aggresomes, which contain misfolded proteins that
Externí odkaz:
https://doaj.org/article/fe1903cfb4524510a2ed45ce3b75f177
Autor:
Paola Caroppo, Giorgio Giaccone, Elena Piccoli, Andrea Salmaggi, Giuliano Sozzi, Gabor G. Kovacs, Veronica Redaelli, Emanuela Maderna, Fabrizio Tagliavini, Marina Grisoli, Sonia Spinello, Giacomina Rossi, Francesca Cacciatore
Publikováno v:
Brain Pathology. 28:72-76
Null mutations in progranulin gene (GRN) reduce the progranulin production resulting in haploinsufficiency and are tightly associated with tau-negative frontotemporal lobar degeneration with TAR DNA-binding protein 43-positive inclusions (FTLD-TDP).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ba60afeabd937a12e3381101a6f1619
https://doi.org/10.1111/bpa.12480
https://doi.org/10.1111/bpa.12480
Autor:
Massimiliano Godani, Francesca Cacciatore, Sonia Spinello, Valeria Fugnanesi, Michela Morbin, Riccardo Zoia, Fabrizio Tagliavini, Giorgio Giaccone, Emanuela Maderna
Publikováno v:
Brain Pathology. 26:542-546
Tauopathies are sporadic or familial neurodegenerative diseases characterized by the accumulation of phosphorylated tau in neurons and glial cells and include encephalitis related to measles virus such as subacute sclerosing panencephalitis. We descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::260a4d6fa1bf5da9f8df618183a33d3b
https://doi.org/10.1111/bpa.12332
https://doi.org/10.1111/bpa.12332
Autor:
Antonio Silvani, Mariangela Farinotti, Rosina Paterra, Bianca Pollo, Gaetano Finocchiaro, Monica Patanè, Sonia Spinello, Francesco DiMeco, Chiara Calatozzolo
Giant cell glioblastoma (gcGBM) is a rare (5 years), higher than in the standard group. The main findings where partial loss of expression of MMR proteins (overall MSH2 and MSH6) on 30% of cases, mostly related to presence of inflammatory infiltrates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b51b26883b07724cd3a85e4401e725
https://europepmc.org/articles/PMC6216707/
https://europepmc.org/articles/PMC6216707/
Autor:
Sonia Spinello, Giorgio Giaccone, Gianni Pezzoli, Stefano Goldwurm, Damiana Rusconi, Manuela Bramerio, Marcello Gambacorta, Fabrizio Tagliavini, Michela Zini, Claudio Ruffmann
Publikováno v:
Acta neuropathologica. 123(6)
There are only two reports of neuropathological findings in heterozygotes for Parkin (PARK2) mutation [3, 5]. One was a normal individual bearing an exon 3 deletion, who at autopsy (at age 93) revealed the absence of a-synuclein pathology and no neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa00e745618df5c952b92fbb2c209e72
https://pubmed.ncbi.nlm.nih.gov/22555654
https://pubmed.ncbi.nlm.nih.gov/22555654