Chemical tuning for potential antitumor fluoroquinolones

Autor: Sonia Soldevila, Guillermo Garcia-Lainez, Francisco Bosca, Inmaculada Andreu, Cristina Anaya-Gonzalez

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia

[EN] Phototoxic effects of 6,8 dihalogenated quinolones confers to this type of molecules a potential property as photochemotherapeutic agents. Two photodehalogenation processes seem to be involved in the remarkable photoinduced cellular damage. In t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ced178aa71b9dbf9dff5d6d8da7bb87
https://doi.org/10.1016/j.freeradbiomed.2019.06.010

Understanding of the Photoallergic Properties of Fluoroquinolones: Photoreactivity of Lomefloxacin with Amino Acids and Albumin

Autor: M. Consuelo Cuquerella, Francisco Bosca, Sonia Soldevila

Publikováno v: RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
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Although the phototoxic and photoallergic properties of fluoroquinolone antibiotics (FQ) are remarkable, the mechanisms involved in these processes are not completely understood. For this reason, it is considered worthwhile to study in detail the pho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f405a53225225625a813c74acf222164
https://doi.org/10.1021/tx400377s

Triplet Excimers of Fluoroquinolones in Aqueous Media

Autor: Inmaculada Andreu, Sonia Soldevila, M. Consuelo Cuquerella, Francisco Bosca

Publikováno v: RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
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Generation of triplet eximers of 6-fluoro-7-piperazinylquinolone-3-carboxylic acids (FQs) have been detected in aqueous media using laser flash photolysis (LFP). These transient species (SS) are generated by self-quenching reactions of FQ triplet exc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ab37504f4080b7e8348a534efa6bcf
https://doi.org/10.1021/jp301800q

Corrigendum to 'Seeking the mechanism responsible for the fluoroquinolone photomutagenicity: A pulse radiolysis, steady-state and laser flash photolysis study' [Free Radic. Biol. Med. 67 (2014) 417–425]

Autor: Ruth Edge, Francisco Bosca, M. Consuelo Cuquerella, Sonia Soldevila, Virginie Lhiaubet-Vallet

Publikováno v: Free Radical Biology and Medicine. 99:624

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7810b24652159cb460e104fb553cee
https://doi.org/10.1016/j.freeradbiomed.2016.08.020