Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sonia Rodriguez-Rodriguez"'
Autor:
Silvia Pomella, Matteo Cassandri, Lucrezia D’Archivio, Antonella Porrazzo, Cristina Cossetti, Doris Phelps, Clara Perrone, Michele Pezzella, Antonella Cardinale, Marco Wachtel, Sara Aloisi, David Milewski, Marta Colletti, Prethish Sreenivas, Zoë S. Walters, Giovanni Barillari, Angela Di Giannatale, Giuseppe Maria Milano, Cristiano De Stefanis, Rita Alaggio, Sonia Rodriguez-Rodriguez, Nadia Carlesso, Christopher R. Vakoc, Enrico Velardi, Beat W. Schafer, Ernesto Guccione, Susanne A. Gatz, Ajla Wasti, Marielle Yohe, Myron Ignatius, Concetta Quintarelli, Janet Shipley, Lucio Miele, Javed Khan, Peter J. Houghton, Francesco Marampon, Berkley E. Gryder, Biagio De Angelis, Franco Locatelli, Rossella Rota
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Rhabdomyosarcomas (RMS) are pediatric mesenchymal-derived malignancies encompassing PAX3/7-FOXO1 Fusion Positive (FP)-RMS, and Fusion Negative (FN)-RMS with frequent RAS pathway mutations. RMS express the master myogenic transcription factor
Externí odkaz:
https://doaj.org/article/b02d638fdabc4c31acb1630b1acf4c96
Autor:
Xiaoguang Wang, Canping Chen, Dan Vuong, Sonia Rodriguez-Rodriguez, Vi Lam, Carly Roleder, Jing H. Wang, Swetha Kambhampati, Allison Berger, Nathan Pennock, Pallawi Torka, Francisco Hernandez-Ilizaliturri, Tanya Siddiqi, Lili Wang, Zheng Xia, Alexey V. Danilov
Publikováno v:
Leukemia.
Neddylation is a sequential enzyme-based process which regulates the function of E3 Cullin-RING ligase (CRL) and thus degradation of substrate proteins. Here we show that CD8+ T cells are a direct target for therapeutically relevant anti-lymphoma act
Autor:
Sonia Rodriguez-Rodriguez, Bin Zhang, Russell C. Rockne, Marcin Kortylewski, Huafeng Wang, Herman Wu, Yu-Lin Su, Brian Armstrong, Dinh Hoa Hoang, Haojie Dong, Jianjun Chen, Guido Marcucci, Nadia Carlesso, Ya-Huei Kuo, Ling Li, Flavia Pichiorri, Lucy Ghoda, Dandan Zhao, Danilo Perrotti, Samer K. Khaled, Le Xuan Truong Nguyen
Publikováno v:
Leukemia. 35(8)
We report here on a novel pro-leukemogenic role of FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) that interferes with microRNAs (miRNAs) biogenesis in acute myeloid leukemia (AML) blasts. We showed that FLT3-ITD interferes with th
Publikováno v:
Experimental Hematology. 88:S76
Acute Lymphoblastic Leukemia (ALL) is the most common pediatric cancer. Despite marked clinical successes in the treatment of childhood T-ALL, leukemia relapse, refractory disease and induction failure (≈ 30% of patients) remain significant clinica
Autor:
Joseph A. Morgan, Sonia Rodriguez-Rodriguez, Edward F. Srour, Nadia Carlesso, Brahmananda R. Chitteti, Drew A. Streicher, Ying Hua Cheng, Melissa A. Kacena
Publikováno v:
Journal of Bone and Mineral Research
Osteoblasts (OBs) exert a prominent regulatory effect on hematopoietic stem cells (HSCs). We evaluated the difference in hematopoietic expansion and function in response to co-culture with OBs at various stages of development. Murine calvarial OBs we
Autor:
Mark H. Kaplan, Lin Wang, Mark Y. Chiang, Mark Wunderlich, Joycelynne Palmer, Purvi Mehrotra, Amy Zollman, James C. Mulloy, Hujia Zhang, Angelo A. Cardoso, Mary A. Yui, George E. Sandusky, Sonia Rodriguez-Rodriguez, Nadia Carlesso
Publikováno v:
Experimental Hematology. 64:S98
Despite marked clinical successes in the treatment of childhood T-ALL, leukemia relapse, refractory disease and induction failure (around 30% of patients) remain significant clinical problems. New insights in the molecular alterations of ALL have rev
Autor:
Brahmananda R. Chitteti, Sonia Rodriguez-Rodriguez, W. Scott Goebel, Ying Hua Cheng, Edward F. Srour, Bradley Poteat, Melissa A. Kacena, Nadia Carlesso
Publikováno v:
Blood. 115:3239-3248
Hematopoietic stem (HSC) and progenitor (HPC) cell fate is governed by intrinsic and extrinsic parameters. We examined the impact of hematopoietic niche elements on HSC and HPC function by analyzing the combined effect of osteoblasts (OBs) and stroma
Autor:
Drew A. Streicher, Melissa A. Kacena, Sonia Rodriguez-Rodriguez, Edward F. Srour, Brahmananda R. Chitteti, Ying Hua Cheng, Nadia Carlesso
Although osteoblasts (OB) play a key role in the hematopoietic stem cell (HSC) niche, little is known as to which specific OB lineage cells are critical for the enhancement of stem and progenitor cell function. Unlike hematopoietic cells, OB cell sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f176cc9b12bb143ed6bd08b2ab411829
https://europepmc.org/articles/PMC3050482/
https://europepmc.org/articles/PMC3050482/
Autor:
Lin Wang, Nadia Carlesso, Angelo A. Cardoso, Sonia Rodriguez-Rodriguez, Amy Zollman, Huajia Zhang
Publikováno v:
Blood. 124:2214-2214
Acute Lymphoblastic Leukemia (ALL) is the most common pediatric cancer. Despite the significant clinical successes in the treatment of pediatric T-ALL, leukemia relapse, refractory disease and induction failure (around 30% of patients) remain signifi
Autor:
Sonia Rodriguez-Rodriguez, Huajia Zhang, Angelo A. Cardoso, Nadia Carlesso, Amy Zollman, Lin Wang
Publikováno v:
Blood. 122:1272-1272
Acute Lymphoblastic Leukemia (ALL) is the most common malignancy in childhood, accounting for almost 30% of pediatric cancers. In pediatric T-cell acute lymphoblastic leukemia (T-ALL), around 30% of the children still undergo disease relapse, which i