Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sonia R. Veiga"'
Autor:
Aina Lluch, Sonia R. Veiga, Jèssica Latorre, José M. Moreno-Navarrete, Núria Bonifaci, Van Dien Nguyen, You Zhou, Marcus Höring, Gerhard Liebisch, Vesa M. Olkkonen, David Llobet-Navas, George Thomas, Ruth Rodríguez-Barrueco, José M. Fernández-Real, Sara C. Kozma, Francisco J. Ortega
Publikováno v:
JCI Insight, Vol 7, Iss 14 (2022)
The ribosomal protein S6 kinase 1 (S6K1) is a relevant effector downstream of the mammalian target of rapamycin complex 1 (mTORC1), best known for its role in the control of lipid homeostasis. Consistent with this, mice lacking the S6k1 gene have a d
Externí odkaz:
https://doaj.org/article/fd58ace89a53441583d2cf1df43a3a08
Autor:
Sonia R. Veiga, Hala Elnakat Thomas, Yu Zhang, George Thomas, Carol A. Mercer, Sara C. Kozma, Jonathan A. Stefely
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Cell reports
Universidad de Barcelona
Cell reports
SUMMARY Cells adapt to nutrient and energy deprivation by inducing autophagy, which is regulated by the mammalian target of rapamycin (mTOR) and AMPactivated protein kinases (AMPKs). We found that cell metabolism significantly influences the ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d50b6df26f7c4bf40fde7179353d13
http://hdl.handle.net/2445/172232
http://hdl.handle.net/2445/172232
Publikováno v:
mTOR Inhibition for Cancer Therapy: Past, Present and Future ISBN: 9782817804910
Phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) signaling is required for normal development, growth, and physiology. Mutations in multiple key regulators of this pathway have been reported to occur leading to aberrant signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::887e632f7193444e83f818b5aade3e58
https://doi.org/10.1007/978-2-8178-0492-7_2
https://doi.org/10.1007/978-2-8178-0492-7_2
Autor:
Constanza L, Cortes, Sonia R, Veiga, Eugènia, Almacellas, Javier, Hernández-Losa, Joan C, Ferreres, Sara C, Kozma, Santiago, Ambrosio, George, Thomas, Albert, Tauler
Publikováno v:
Molecular Cancer
Background Neuroblastoma is a malignant embryonal tumor occurring in young children, consisting of undifferentiated neuroectodermal cells derived from the neural crest. Current therapies for high-risk neuroblastoma are insufficient, resulting in high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7076da74d9430f4b157229219f08126
https://pubmed.ncbi.nlm.nih.gov/26728659
https://pubmed.ncbi.nlm.nih.gov/26728659
Autor:
George Thomas, Xuemei Ge, Santiago Ramón y Cajal, Carol A. Mercer, Hala Elnakat Thomas, María Isabel Hernández-Alvarez, Javier Hernández-Losa, Sonia R. Veiga, Sara C. Kozma, Antonio Zorzano
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Purpose: Hepatocellular carcinoma (HCC) ranks second in cancer mortality and has limited therapeutic options. We recently described the synergistic effect of allosteric and ATP-site competitive inhibitors against the mTOR for the treatment of HCC. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37824bf783cc12d16f18ffd4e824035f
http://hdl.handle.net/2445/125570
http://hdl.handle.net/2445/125570