Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Sonia Missiroli"'
Autor:
Caterina Licini, Gianluca Morroni, Guendalina Lucarini, Veronica Angela Maria Vitto, Fiorenza Orlando, Sonia Missiroli, Gloria D’Achille, Mariasole Perrone, Tatiana Spadoni, Laura Graciotti, Giorgia Bigossi, Mauro Provinciali, Annamaria Offidani, Monica Mattioli-Belmonte, Oscar Cirioni, Paolo Pinton, Oriana Simonetti, Saverio Marchi
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-14 (2024)
Abstract Methicillin-resistant Staphylococcus aureus (MRSA) is the most common causative agent of acute bacterial skin and skin-structure infections (ABSSSI), one of the major challenges to the health system worldwide. Although the use of antibiotics
Externí odkaz:
https://doaj.org/article/d5072a9c5e064288afa11138aa5e5a7f
Autor:
Amelie Raby, Sonia Missiroli, Peggy Sanatine, Dominique Langui, Julien Pansiot, Nissai Beaude, Lucie Vezzana, Rachelle Saleh, Martina Marinello, Mireille Laforge, Paolo Pinton, Ana Buj-Bello, Andrea Burgo
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110683- (2024)
Summary: Mitochondria-endoplasmic reticulum (ER) contact sites (MERCs) emerged to play critical roles in numerous cellular processes, and their dysregulation has been associated to neurodegenerative disorders. Mutations in the SPG4 gene coding for sp
Externí odkaz:
https://doaj.org/article/7c8d77dc77d541b690d64de75d52c7d1
Autor:
Laura Palumbo, Marianna Carinci, Annunziata Guarino, Laila Asth, Silvia Zucchini, Sonia Missiroli, Alessandro Rimessi, Paolo Pinton, Carlotta Giorgi
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2825 (2023)
Neuroinflammation represents a dynamic process of defense and protection against the harmful action of infectious agents or other detrimental stimuli in the central nervous system (CNS). However, the uncontrolled regulation of this physiological proc
Externí odkaz:
https://doaj.org/article/35a28d26c0a341e4a0ce617dd94f50be
Autor:
David Liang, Liping Jiang, Sameer Ahmed Bhat, Sonia Missiroli, Mariasole Perrone, Angela Lauriola, Ritika Adhikari, Anish Gudur, Zahra Vasi, Ian Ahearn, Daniele Guardavaccaro, Carlotta Giorgi, Mark Philips, Shafi Kuchay
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111999- (2023)
Summary: Substrate degradation by the ubiquitin proteasome system (UPS) in specific membrane compartments remains elusive. Here, we show that the interplay of two lipid modifications and PDE6δ regulates compartmental substrate targeting via the SCFF
Externí odkaz:
https://doaj.org/article/d663d5a395244e3bab84b46f3f717660
Autor:
Ettore Silvagni, Sonia Missiroli, Mariasole Perrone, Simone Patergnani, Caterina Boncompagni, Alessandra Bortoluzzi, Marcello Govoni, Carlotta Giorgi, Stefano Alivernini, Paolo Pinton, Carlo Alberto Scirè
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Psoriatic arthritis (PsA) is a chronic inflammatory immune-mediated disease with a burdensome impact on quality of life and substantial healthcare costs. To date, pharmacological interventions with different mechanisms of action, including convention
Externí odkaz:
https://doaj.org/article/bf9d5273defd473da7a5cb0d588e3925
Autor:
Diego Pozzer, Ersilia Varone, Alexander Chernorudskiy, Silvia Schiarea, Sonia Missiroli, Carlotta Giorgi, Paolo Pinton, Marta Canato, Elena Germinario, Leonardo Nogara, Bert Blaauw, Ester Zito
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 354-366 (2019)
Selenoprotein N (SELENON) is an endoplasmic reticulum (ER) protein whose loss of function leads to human SELENON-related myopathies. SelenoN knockout (KO) mouse limb muscles, however, are protected from the disease, and display no major alterations i
Externí odkaz:
https://doaj.org/article/000c6ab7e1f04ce9b8dd36fad86f36bb
Publikováno v:
EBioMedicine, Vol 59, Iss , Pp 102943- (2020)
Mitochondria are dynamic organelles that have essential metabolic activity and are regarded as signalling hubs with biosynthetic, bioenergetics and signalling functions that orchestrate key biological pathways. However, mitochondria can influence all
Externí odkaz:
https://doaj.org/article/56dc59a669984f21b7a3eeb0561d1541
Autor:
Sonia Missiroli, Massimo Bonora, Simone Patergnani, Federica Poletti, Mariasole Perrone, Roberta Gafà, Eros Magri, Andrea Raimondi, Giovanni Lanza, Carlo Tacchetti, Guido Kroemer, Pier Paolo Pandolfi, Paolo Pinton, Carlotta Giorgi
Publikováno v:
Cell Reports, Vol 16, Iss 9, Pp 2415-2427 (2016)
The precise molecular mechanisms that coordinate apoptosis and autophagy in cancer remain to be determined. Here, we provide evidence that the tumor suppressor promyelocytic leukemia protein (PML) controls autophagosome formation at mitochondria-asso
Externí odkaz:
https://doaj.org/article/2d6efb2bd9824461bd46909dade1fae1
Autor:
Saverio Marchi, Mariangela Corricelli, Eliana Trapani, Luca Bravi, Alessandra Pittaro, Simona Delle Monache, Letizia Ferroni, Simone Patergnani, Sonia Missiroli, Luca Goitre, Lorenza Trabalzini, Alessandro Rimessi, Carlotta Giorgi, Barbara Zavan, Paola Cassoni, Elisabetta Dejana, Saverio Francesco Retta, Paolo Pinton
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 11, Pp 1403-1417 (2015)
Abstract Cerebral cavernous malformation (CCM) is a major cerebrovascular disease affecting approximately 0.3–0.5% of the population and is characterized by enlarged and leaky capillaries that predispose to seizures, focal neurological deficits, an
Externí odkaz:
https://doaj.org/article/5b50193f8a5849aebd091244eb7e131d
Autor:
Valentina Albanese, Sonia Missiroli, Mariasole Perrone, Martina Fabbri, Caterina Boncompagni, Salvatore Pacifico, Tiziano De Ventura, Antonella Ciancetta, Giulio Dondio, Franz Kricek, Paolo Pinton, Remo Guerrini, Delia Preti, Carlotta Giorgi
Publikováno v:
Journal of Medicinal Chemistry. 66:5223-5241
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a4be00c473927b0c7ea7574b68d6a09
https://doi.org/10.1021/acs.jmedchem.3c00175
https://doi.org/10.1021/acs.jmedchem.3c00175