Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sonia M Amaral"'
Autor:
Sarah W Joseph, Doriano Fabbro, Ifor R. Williams, Sonia M Amaral, James D. Griffin, Nicole Duclos, Christina L. Boulton, Brian J. P. Huntly, D. G. Gilliland, Benjamin H. Lee, David P. Curley, Ema Anastasiadou
Publikováno v:
Oncogene. 24(53)
Activating FMS-like tyrosine kinase 3 (FLT3) mutations have been identified in approximately 30% of patients with acute myelogenous leukemia (AML), and recently in a smaller subset of patients with acute lymphoblastic leukemia (ALL). To explore the i
Autor:
Christina L. Boulton, Ifor R. Williams, Robert D. Legare, Doriano Fabbro, Daniel J. DeAngelo, Jason Gotlib, Elizabeth H. Stover, Thomas Meyer, Ellen Weisberg, Peter Marynen, D. Gary Gilliland, Jan Cools, Nicole Duclos, Richard Stone, Paul W. Manley, Sonia M Amaral, Benjamin H. Lee, Donna Neuberg, James D. Griffin, David P. Curley, Steven Coutre, Rebecca Rowan, Jeffery L. Kutok
Publikováno v:
Cancer cell. 3(5)
FIP1L1-PDGFRalpha causes hypereosinophilic syndrome (HES) and is inhibited by the tyrosine kinase inhibitor imatinib (Gleevec). Imatinib is a potent inhibitor of ABL, ARG, PDGFRalpha, PDGFRbeta, and KIT and induces durable hematologic responses in HE
Autor:
Jeffrey L. Kutok, Ifor R. Williams, Christina L. Boulton, Timothy J. Ley, D. Gary Gilliland, Louise M Kelly, Sonia M Amaral, David P. Curley
Acute promyelocytic leukemia (APL) cells invariably express aberrant fusion proteins involving the retinoic acid receptor α (RARα). The most common fusion partner is promyelocytic leukemia protein (PML), which is fused to RARα in the balanced reci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1afdd194aaf6f714af5c56d6f05aa39
https://europepmc.org/articles/PMC123059/
https://europepmc.org/articles/PMC123059/
Autor:
Shinichi Mizuno, Rebecca Rowan, Koichi Akashi, Ifor R. Williams, D. Gary Gilliland, Sonia M Amaral, Benjamin H. Lee, Hirokazu Shigematsu, David P. Curley, Kenji Deguchi, Brian J. P. Huntly, Nicky Duclos
Publikováno v:
Blood. 104:62-62
The existence of leukemia stem cells has been demonstrated in acute myeloid and lymphoblastic leukemias (AML and ALL). The origins of these cells are unknown, but it has been suggested that they result from the transformation of adult hematopoietic s