Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Sonia Kiran"'
Publikováno v:
Bioactive Materials, Vol 36, Iss , Pp 301-316 (2024)
Natural killer (NK) cells are cytotoxic immune cells that can eliminate target cells without prior stimulation. Human induced pluripotent stem cells (iPSCs) provide a robust source of NK cells for safe and effective cell-based immunotherapy against a
Externí odkaz:
https://doaj.org/article/60e23d6bd9644ea891c510a9c136de24
Publikováno v:
Bioactive Materials, Vol 31, Iss , Pp 136-150 (2024)
Atypical teratoid/rhabdoid tumor (ATRT) is a rare childhood malignancy that originates in the central nervous system. Over ninety-five percent of ATRT patients have biallelic inactivation of the tumor suppressor gene SMARCB1. ATRT has no standard tre
Externí odkaz:
https://doaj.org/article/981b6c5fed0d4886baa275cc660f7cf4
Autor:
Silpa Gampala, Hye-ran Moon, Randall Wireman, Jacqueline Peil, Sonia Kiran, Dana K. Mitchell, Kylee Brewster, Henry Mang, Andi Masters, Christine Bach, Whitney Smith-Kinnamen, Emma H. Doud, Ratan Rai, Amber L. Mosley, Sara K. Quinney, D. Wade Clapp, Chafiq Hamdouchi, James Wikel, Chi Zhang, Bumsoo Han, Millie M. Georgiadis, Mark R. Kelley, Melissa L. Fishel
Publikováno v:
Pharmacological Research, Vol 201, Iss , Pp 107092- (2024)
AP endonuclease-1/Redox factor-1 (APE1/Ref-1 or Ref-1) is a multifunctional protein that is overexpressed in most aggressive cancers and impacts various cancer cell signaling pathways. Ref-1′s redox activity plays a significant role in activating t
Externí odkaz:
https://doaj.org/article/aab80d4f3cdf4047a242a19cd4eadd78
Publikováno v:
Immunity & Ageing, Vol 19, Iss 1, Pp 1-18 (2022)
Abstract Obesity is characterized by an elevated amount of fat and energy storage in the adipose tissue (AT) and is believed to be the root cause of many metabolic diseases (MDs). Obesity is associated with low-grade chronic inflammation in AT. Like
Externí odkaz:
https://doaj.org/article/93efb2c49933400598c51edecd8aa207
Autor:
Timothy Hua, Chang Liu, Sonia Kiran, Kelly Gray, Sunghoon Jung, David G. Meckes, Yan Li, Qing-Xiang Amy Sang
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Human cerebellum consists of high density and complexity of neurons. Thus, it is challenging to differentiate cerebellar-like organoids with similar cellular markers and function to the human brain. Our previous study showed that the combina
Externí odkaz:
https://doaj.org/article/7cc3b09809f64216b8536cb129da05e8
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundObesity is a multifactorial disease characterized by an enhanced amount of fat and energy storage in adipose tissue (AT). Obesity appears to promote and maintain low-grade chronic inflammation by activating a subset of inflammatory T cells,
Externí odkaz:
https://doaj.org/article/d522ecfdea804b7c80f261baf608dd9a
Autor:
Ahmed Rakib, Mousumi Mandal, Anaum Showkat, Sonia Kiran, Soumi Mazumdar, Bhupesh Singla, Aman Bajwa, Santosh Kumar, Frank Park, Udai P. Singh
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 161, Iss , Pp 114514- (2023)
The beneficial effects of the polyphenolic compound piceatannol (PC) has been reported for metabolic diseases, antiproliferative, antioxidant, and anti-cancer properties. Despite its beneficial effects on inflammatory diseases, little is known about
Externí odkaz:
https://doaj.org/article/e39534e848274f41a2f75c116b18d7ec
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Interstitial cystitis (IC)/bladder pain syndrome (BPS), hereafter referred together as IC, is a clinical syndrome characterized by sterile inflammation in the bladder. While the etiology and pathophysiology of IC remain unclear, it may involve autoim
Externí odkaz:
https://doaj.org/article/7636196e2c7d46ee8075e51eb730c4c3
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Interstitial cystitis (IC)/bladder pain syndrome (BPS) primarily affects women. It varies in its severity and currently has no effective treatment. The symptoms of IC include pelvic pain, urgency and frequency of urination, and discomfort or pain in
Externí odkaz:
https://doaj.org/article/ec2d6adf9c28469aad5496f4bf51575f
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Obesity in the United States and worldwide reached epidemic proportions within the last 20 years. Obesity is a very powerful health determinant or indicator that facilitates the development and progression of several metabolic diseases, insulin resis
Externí odkaz:
https://doaj.org/article/b3aa66edd41f464881680fa7787dbbbf