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pro vyhledávání: '"Sonia K Bhasin"'
Autor:
Nicholas Noinaj, Sonia K Bhasin, Eun Suk Song, Kirsten E Scoggin, Maria A Juliano, Luiz Juliano, Louis B Hersh, David W Rodgers
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20864 (2011)
Insulin degrading enzyme (IDE) is responsible for the metabolism of insulin and plays a role in clearance of the Aβ peptide associated with Alzheimer's disease. Unlike most proteolytic enzymes, IDE, which consists of four structurally related domain
Externí odkaz:
https://doaj.org/article/8edf4ef80c394c65aa9c037723daeca9
Autor:
Benjamin J. Alper, David W. Rodgers, Louis B. Hersh, Nicholas Noinaj, Eun Suk Song, Walter K. Schmidt, Sonia K. Bhasin
Publikováno v:
The Journal of biological chemistry. 287(1)
Insulin-degrading enzyme (IDE) (insulysin) is a zinc metallopeptidase that metabolizes several bioactive peptides, including insulin and the amyloid β peptide. IDE is an unusual metallopeptidase in that it is allosterically activated by both small p
Autor:
Sonia K. Bhasin, Louis B. Hersh, Luiz Juliano, Kirsten E. Scoggin, David W. Rodgers, Eun Suk Song, Maria A. Juliano, Nicholas Noinaj
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 6, p e20864 (2011)
PLoS ONE, Vol 6, Iss 6, p e20864 (2011)
Background Insulin degrading enzyme (IDE) is responsible for the metabolism of insulin and plays a role in clearance of the Aβ peptide associated with Alzheimer's disease. Unlike most proteolytic enzymes, IDE, which consists of four structurally rel