Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sonia I Barroso"'
Autor:
Marta Giannini, Aleix Bayona-Feliu, Daisy Sproviero, Sonia I Barroso, Cristina Cereda, Andrés Aguilera
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1009260 (2020)
TDP-43 is a DNA and RNA binding protein involved in RNA processing and with structural resemblance to heterogeneous ribonucleoproteins (hnRNPs), whose depletion sensitizes neurons to double strand DNA breaks (DSBs). Amyotrophic Lateral Sclerosis (ALS
Externí odkaz:
https://doaj.org/article/d695da3ae0b64c96911d89211d59eced
Autor:
María L García-Rubio, Carmen Pérez-Calero, Sonia I Barroso, Emanuela Tumini, Emilia Herrera-Moyano, Iván V Rosado, Andrés Aguilera
Publikováno v:
PLoS Genetics, Vol 11, Iss 11, p e1005674 (2015)
Co-transcriptional RNA-DNA hybrids (R loops) cause genome instability. To prevent harmful R loop accumulation, cells have evolved specific eukaryotic factors, one being the BRCA2 double-strand break repair protein. As BRCA2 also protects stalled repl
Externí odkaz:
https://doaj.org/article/f837cc8569b3404c8b6b85ce1a4f0b64
Autor:
Despoina Sakellariou, Sara Thornby Bak, Esin Isik, Sonia I. Barroso, Antonio Porro, Andrés Aguilera, Jiri Bartek, Pavel Janscak, Javier Peña-Diaz
Publikováno v:
Cell Reports, Vol 39, Iss 1, Pp 110602- (2022)
Summary: Up to 15% of human cancers maintain their telomeres through a telomerase-independent mechanism, termed “alternative lengthening of telomeres” (ALT) that relies on homologous recombination between telomeric sequences. Emerging evidence su
Externí odkaz:
https://doaj.org/article/8631f972ac8d4c67b4727780e3bd2090
Publikováno v:
Methods in Molecular Biology ISBN: 9781071606438
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8873433a3613015790171a287b69b4ff
https://doi.org/10.1007/978-1-0716-0644-5
https://doi.org/10.1007/978-1-0716-0644-5
Autor:
Sonia I, Barroso, Andrés, Aguilera
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2153
DNA double-strand breaks (DSBs) are the most deleterious type of DNA damage and a cause of genetic instability as they can lead to mutations, genome rearrangements, or loss of genetic material when not properly repaired. Eukaryotes from budding yeast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33a73dcba4284d716341df9226fe9fb8
https://pubmed.ncbi.nlm.nih.gov/32840768
https://pubmed.ncbi.nlm.nih.gov/32840768
Autor:
Martin Kosar, Michele Giannattasio, Daniele Piccini, Apolinar Maya-Mendoza, Francisco García-Benítez, Jirina Bartkova, Sonia I. Barroso, Hélène Gaillard, Emanuele Martini, Umberto Restuccia, Miguel Angel Ramirez-Otero, Massimiliano Garre, Eleonora Verga, Miguel Andújar-Sánchez, Scott Maynard, Zdenek Hodny, Vincenzo Costanzo, Amit Kumar, Angela Bachi, Andrés Aguilera, Jiri Bartek, Marco Foiani
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Tpr nucleoporin is known to be essential for nuclear transport and mitosis processes. Here the authors explore the link between Tpr and genome instability providing insights into the role of Tpr in safeguarding cells from RNA-mediated replication str
Externí odkaz:
https://doaj.org/article/18fbf66c3f8442a6835b1d14c7f9ffa2
Autor:
Alba Duch, Berta Canal, Sonia I. Barroso, María García-Rubio, Gerhard Seisenbacher, Andrés Aguilera, Eulàlia de Nadal, Francesc Posas
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
During S phase of the cell cycle, transcription and replication need to be coordinated in order to avoid conflicts leading to potential genomic instability. Here, the authors find that Mrc1 integrates signals from different kinases to regulate replic
Externí odkaz:
https://doaj.org/article/890cd55d01074eb4acae28ff6220fd5b