Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sonia Gullón"'
Publikováno v:
BMC Microbiology, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background Streptomyces lividans is an appealing host for the production of proteins of biotechnological interest due to its relaxed exogenous DNA restriction system and its ability to secrete proteins directly to the medium through the majo
Externí odkaz:
https://doaj.org/article/770ad790f87846c2a00039cca34a9465
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-9 (2019)
Abstract Background Bacterial secretory proteins often require the formation of disulphide bonds outside the cell to acquire an active conformation. Thiol-disulphide oxidoreductases are enzymes that catalyse the formation of disulphide bonds. The bac
Externí odkaz:
https://doaj.org/article/5476d636c52e464baf00c8470b37bce7
Publikováno v:
BMC Microbiology, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background Streptomyces lividans has demonstrated its value as an efficient host for protein production due to its ability to secrete functional proteins directly to the media. Secretory proteins that use the major Sec route need to be prope
Externí odkaz:
https://doaj.org/article/360e4fc8e8574a9b93ac146e392e4874
Autor:
Esmeralda Cebrián-Sastre, Isabel Martín-Blecua, Sonia Gullón, Jesús Blázquez, Alfredo Castañeda-García
Publikováno v:
Cells, Vol 10, Iss 6, p 1314 (2021)
The DNA repair endonuclease EndoMS/NucS is highly conserved in Archaea and Actinobacteria. This enzyme is able to recognize and cleave dsDNA carrying a mismatched base pair, and its activity is enhanced by the interaction with the sliding clamp of th
Externí odkaz:
https://doaj.org/article/65e50d7a5375484db0828e7e35827bc0
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165204 (2016)
Biological communities present in soil are essential to sustainable and productive agricultural practices; however, an accurate determination of the ecological status of agricultural soils remains to date an elusive task. An ideal indicator should be
Externí odkaz:
https://doaj.org/article/c06bae37564a44f4b5399ca3ab7c0310
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168112 (2016)
Overproduction of Sec-proteins in S. lividans accumulates misfolded proteins outside of the cytoplasmic membrane where the accumulated proteins interfere with the correct functioning of the secretion machinery and with the correct cell functionality,
Externí odkaz:
https://doaj.org/article/c34ad011ccfa44da888437af392d0094
Autor:
Sonia Gullón, Rafael P. Mellado
Publikováno v:
Antibiotics, Vol 7, Iss 2, p 33 (2018)
Gram-positive soil bacteria included in the genus Streptomyces produce a large variety of secondary metabolites in addition to extracellular hydrolytic enzymes. From the industrial and commercial viewpoints, the S. lividans strain has generated great
Externí odkaz:
https://doaj.org/article/6a77d4a7da394f7b8fe379c872e88542
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133645 (2015)
Streptomyces lividans is considered an efficient host for the secretory production of homologous and heterologous proteins. To identify possible bottlenecks in the protein production process, a comparative transcriptomic approach was adopted to study
Externí odkaz:
https://doaj.org/article/3647a309b3ba4c188bcf471ef2b31729
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31760 (2012)
BACKGROUND: Bacterial two-component signal transduction regulatory systems are the major set of signalling proteins frequently mediating responses to changes in the environment. They typically consist of a sensor, a membrane-associated histidine kina
Externí odkaz:
https://doaj.org/article/7b3dfcccdd024688862f7eaf315af944
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48987 (2012)
BACKGROUND: Misfolded proteins accumulating outside the bacterial cytoplasmic membrane can interfere with the secretory machinery, hence the existence of quality factors to eliminate these misfolded proteins is of capital importance in bacteria that
Externí odkaz:
https://doaj.org/article/12ff9bfd382c40b29385ad9877c04baf