Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sonia Ghilas"'
Autor:
Sharon Tran, Juliani Juliani, Tiffany J. Harris, Marco Evangelista, Julian Ratcliffe, Sarah L. Ellis, David Baloyan, Camilla M. Reehorst, Rebecca Nightingale, Ian Y. Luk, Laura J. Jenkins, Sonia Ghilas, Marina H. Yakou, Chantelle Inguanti, Chad Johnson, Michael Buchert, James C. Lee, Peter De Cruz, Kinga Duszyc, Paul A. Gleeson, Benjamin T. Kile, Lisa A. Mielke, Alpha S. Yap, John M. Mariadason, W. Douglas Fairlie, Erinna F. Lee
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Autophagy-related genes have been closely associated with intestinal homeostasis. BECLIN1 is a component of Class III phosphatidylinositol 3-kinase complexes that orchestrate autophagy initiation and endocytic trafficking. Here we show intes
Externí odkaz:
https://doaj.org/article/fc863b699bb647f5926120d1c9e15000
Autor:
David Williams, Gabrielle Belz, Wei Shi, Anita Kumari, Andreas Behren, Maxine Smith, Marina Yakou, Sonia Ghilas, Kelly Tran, Yang Liao, Shoukat Afshar-Sterle, Kevin Schmid, Christine Dijkstra, Chantelle Inguanti, Simone Ostrouska, Jordan Wilcox, Pavitha Parathan, Amr Allam, Hai-Hui Xue, John Mariadason, Grant Drummond, Roland Ruscher, Bhupinder Pal, Matthias Ernst, Dinesh Raghu, Lisa A Mielke
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/53e2c7996d52481f9160ae107e1bb5fa
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The gut epithelium not only provides a physical barrier to separate a noxious outside from a sterile inside but also allows for highly regulated interactions between bacteria and their products, and components of the immune system. Homeostatic mainte
Externí odkaz:
https://doaj.org/article/6001a4cb60d94a2ab87c1558bf8667d2
Autor:
Matthias H. Enders, Ganchimeg Bayarsaikhan, Sonia Ghilas, Yu Cheng Chua, Rose May, Maria N. de Menezes, Zhengyu Ge, Peck Szee Tan, Anton Cozijnsen, Vanessa Mollard, Katsuyuki Yui, Geoffrey I. McFadden, Mireille H. Lahoud, Irina Caminschi, Anthony W. Purcell, Ralf B. Schittenhelm, Lynette Beattie, William R. Heath, Daniel Fernandez-Ruiz
Publikováno v:
Current Research in Immunology, Vol 2, Iss , Pp 79-92 (2021)
Thorough understanding of the role of CD4 T cells in immunity can be greatly assisted by the study of responses to defined specificities. This requires knowledge of Plasmodium-derived immunogenic epitopes, of which only a few have been identified, es
Externí odkaz:
https://doaj.org/article/ae70f072848a4eb3bfa16dbb9ca365ca
Autor:
Sonia Ghilas, Marc Ambrosini, Jean-Charles Cancel, Carine Brousse, Marion Massé, Hugues Lelouard, Marc Dalod, Karine Crozat
Publikováno v:
iScience, Vol 24, Iss 9, Pp 103059- (2021)
Summary: Successful immune responses rely on a regulated delivery of the right signals to the right cells at the right time. Here we show that natural killer (NK) and dendritic epidermal γδ T cells (DETCs) use similar mechanisms to spatiotemporally
Externí odkaz:
https://doaj.org/article/d54b1b8a1b4c4075baf41ba89bea284f
Autor:
Raphaël Mattiuz, Christian Wohn, Sonia Ghilas, Marc Ambrosini, Yannick O. Alexandre, Cindy Sanchez, Anissa Fries, Thien-Phong Vu Manh, Bernard Malissen, Marc Dalod, Karine Crozat
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Type 1 conventional DCs (cDC1) excel in the cross-priming of CD8+ T cells, which is crucial for orchestrating efficient immune responses against viruses or tumors. However, our understanding of their physiological functions and molecular regulation h
Externí odkaz:
https://doaj.org/article/b273b8922beb47cebccd18fc34d7b35e
Autor:
Sonia Ghilas, Ana-Maria Valencia-Hernandez, Matthias H. Enders, William R. Heath, Daniel Fernandez-Ruiz
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8565 (2020)
Immunological memory is fundamental to maintain immunity against re-invading pathogens. It is the basis for prolonged protection induced by vaccines and can be mediated by humoral or cellular responses—the latter largely mediated by T cells. Memory
Externí odkaz:
https://doaj.org/article/0a3ae66af1bf46859cdfd85d45d3ea97
Autor:
Lisa A. Mielke, Sonia Ghilas
Publikováno v:
Trends in Immunology. 42:1063-1065
In two elegant studies, Tyler Jacks' group and colleagues unveil crucial interactions between dendritic cells and TCF1+CD8+ progenitor T cells, shaping their heterogeneity and offering potential to design new putative cancer immunotherapies and vacci
Autor:
Daniel Fernandez-Ruiz, Ian A. Cockburn, Anton Cozijnsen, Rose May, Geoffrey I. McFadden, Lynette Beattie, Vanessa Mollard, Matthias H. Enders, Lauren E. Holz, Sonia Ghilas, William R. Heath
Publikováno v:
European Journal of Immunology. 51:1153-1165
Malaria remains a major cause of mortality in the world and an efficient vaccine is the best chance of reducing the disease burden. Vaccination strategies for the liver stage of disease that utilise injection of live radiation-attenuated sporozoites
Autor:
Sonia Ghilas, Maria N. de Menezes, Daniel Fernandez-Ruiz, Lauren E. Holz, Lynette Beattie, William R. Heath
Publikováno v:
Expert Review of Vaccines. 20:127-141
Tissue-resident memory T cells (TRM cells) are powerful mediators of protracted adaptive immunity to infection in peripheral organs. Harnessing TRM cells through vaccination hence promises unpreced...