Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Sonia Franciosi"'
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Sudden cardiac death (SCD) is a rare and devastating event in children and remains a leading cause of death in young athletes. Channelopathies and cardiomyopathies, in particular long QT syndrome (LQTS), catecholaminergic polymorphic ventricular tach
Externí odkaz:
https://doaj.org/article/a22bb8f0e6aa473285c8657b528bd7d3
Autor:
Sonia Franciosi, PhD, Dominic J. Abrams, MBBS, MD, MBA, Jodie Ingles, PhD, MPH, Shubhayan Sanatani, MD, FRCPC, FHRS, CCDS
Publikováno v:
CJC Pediatric and Congenital Heart Disease, Vol 1, Iss 2, Pp 45-59 (2022)
Sudden cardiac arrest in the young is a rare event with a range of potential causes including cardiomyopathies, ion channelopathies, and autonomic nervous system dysfunction. Investigations into the cause involve a multidisciplinary team, including c
Externí odkaz:
https://doaj.org/article/aca32cec006a4b7f825356382753943d
Autor:
Chi Hung Chen, MD, Astrid-Marie De Souza, MSc, Sonia Franciosi, PhD, Kevin C. Harris, MD, Shubhayan Sanatani, MD
Publikováno v:
CJC Pediatric and Congenital Heart Disease, Vol 1, Iss 2, Pp 80-85 (2022)
Background: Physical activity (PA) is important for cardiovascular health as well as social and emotional well-being of children. Patients with long QT syndrome (LQTS) often face PA restrictions and are often prescribed beta-blockers for disease mana
Externí odkaz:
https://doaj.org/article/b2c33f90aab141e5a879f4f78dcc571b
Autor:
Gabrielle Sanatani, Sonia Franciosi, PhD, Jeffrey N. Bone, MSc, Brynn Dechert, RN, MSN, CPNP, CCDS, FHRS, Kevin C. Harris, MD, MHSc, Manish Sadarangani, BM, BCh, FRCPC, DPhil
Publikováno v:
CJC Pediatric and Congenital Heart Disease, Vol 1, Iss 2, Pp 74-79 (2022)
Background: Congenital heart disease, the most common congenital anomaly, often presents in neonates. Because of perceived risks, health care providers may consider deferring immunizations in this population. We sought to understand the perceived ris
Externí odkaz:
https://doaj.org/article/5b5fd4c15a524604bb74e2efdaf9a0ff
Autor:
Nathan Wei, Avani Lamba, BS, Sonia Franciosi, PhD, Ian H. Law, BSE, MD, FHRS, Luis A. Ochoa, MD, Christopher L. Johnsrude, MD, MS, Sit Yee Kwok, MBChB, CEPS-P, Teng Hong Tan, MBBS, Santokh S. Dhillon, MBBS, MD, FHRS, CCDS, Anne Fournier, MD, Stephen P. Seslar, MD, PhD, CCDS, CEPS-P, Elizabeth A. Stephenson, MD, FHRS, CEPS-P, Andrew D. Blaufox, MD, FHRS, CEPS-P, Michel Cabrera Ortega, MD, Jeffrey N. Bone, MSc, Ash Sandhu, BS, Carolina A. Escudero, MD, MS, Shubhayan Sanatani, BS, MD, FHRS, CCDS
Publikováno v:
CJC Pediatric and Congenital Heart Disease, Vol 1, Iss 1, Pp 11-22 (2022)
Background: Several medication choices are available for acute and prophylactic treatment of refractory supraventricular tachycardia (SVT) in infants. There are almost no controlled trials, and medication choices are not necessarily evidence based. O
Externí odkaz:
https://doaj.org/article/f874c503afa1496ebf7e5af3bb422a72
Autor:
Kristina Bečanović, Asghar Muhammad, Izabella Gadawska, Shiny Sachdeva, David Walker, Eduardo. R. Lazarowski, Sonia Franciosi, Kevin H. J. Park, Hélène C. F. Côté, Blair R. Leavitt
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-14 (2021)
Abstract Mitochondrial dysfunction and bioenergetics failure are common pathological hallmarks in Huntington’s disease (HD) and aging. In the present study, we used the YAC128 murine model of HD to examine the effects of mutant huntingtin on mitoch
Externí odkaz:
https://doaj.org/article/9ed44fa1c2f0480fb9c59de967a2f4ca
Autor:
Ming Chang Liu, Matthew A. Tester, BSc, Sonia Franciosi, PhD, Andrew D. Krahn, MD, FHRS, Martin J. Gardner, MD, FRCPC, Jason D. Roberts, MD, MAS, Shubhayan Sanatani, MD, FRCPC, FHRS, CCDS
Publikováno v:
CJC Open, Vol 3, Iss 3, Pp 285-291 (2021)
Background: The etiology of sudden cardiac arrest (SCA) in individuals without known cardiovascular heart disease remains elusive in nearly half of all patients after systematic testing. We investigated the relationship between stressful life events
Externí odkaz:
https://doaj.org/article/5102e790a8444acd8c4c34d1752b1274
Autor:
Dagmar E. Ehrnhoefer, Dale D. O. Martin, Mandi E. Schmidt, Xiaofan Qiu, Safia Ladha, Nicholas S. Caron, Niels H. Skotte, Yen T. N. Nguyen, Kuljeet Vaid, Amber L. Southwell, Sabine Engemann, Sonia Franciosi, Michael R. Hayden
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-16 (2018)
Abstract Huntington disease (HD) is caused by the expression of mutant huntingtin (mHTT) bearing a polyglutamine expansion. In HD, mHTT accumulation is accompanied by a dysfunction in basal autophagy, which manifests as specific defects in cargo load
Externí odkaz:
https://doaj.org/article/3098d7176f61480fbe25947e9399afed
Autor:
Kristina Bečanović, Muhammad Asghar, Izabella Gadawska, Shiny Sachdeva, David Walker, Eduardo. R. Lazarowski, Sonia Franciosi, Kevin H. J. Park, Hélène C. F. Côté, Blair R. Leavitt
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/5efe5a202d054666aa22337aa09ee23d
Autor:
Dania Kallas, Avani Lamba, Thomas M. Roston, Alia Arslanova, Sonia Franciosi, Glen F. Tibbits, Shubhayan Sanatani
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9293 (2021)
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare and potentially lethal inherited arrhythmia disease characterized by exercise or emotion-induced bidirectional or polymorphic ventricular tachyarrhythmias. The median age of disea
Externí odkaz:
https://doaj.org/article/6b4d706bdf844aaab93f67c1c6a317f3