Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sonia Ciudad"'
Autor:
Sonia Ciudad, Eduard Puig, Thomas Botzanowski, Moeen Meigooni, Andres S. Arango, Jimmy Do, Maxim Mayzel, Mariam Bayoumi, Stéphane Chaignepain, Giovanni Maglia, Sarah Cianferani, Vladislav Orekhov, Emad Tajkhorshid, Benjamin Bardiaux, Natàlia Carulla
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Formation of amyloid-beta (Aβ) oligomer pores in the membrane of neurons has been proposed to explain neurotoxicity in Alzheimer´s disease. Here authors present the 3D- structure of an Aβ oligomer formed in a membrane mimicking environment and obs
Externí odkaz:
https://doaj.org/article/2c0e9ea1270e440fb213d992e9ac74ae
Autor:
Emad Tajkhorshid, Eduard Puig, Sonia Ciudad, Thomas Botzanowski, Mariam Bayoumi, Vladislav Yu. Orekhov, Benjamin Bardiaux, Giovanni Maglia, Sarah Cianférani, Andres S. Arango, Stéphane Chaignepain, Jimmy Do, Moeen Meigooni, Natàlia Carulla, Maxim Mayzel
Publikováno v:
Nature Communications, 11(1):3014. Nature Publishing Group
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.3014. ⟨10.1038/s41467-020-16566-1⟩
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, 2020, 11 (1), pp.3014. ⟨10.1038/s41467-020-16566-1⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.3014. ⟨10.1038/s41467-020-16566-1⟩
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, 2020, 11 (1), pp.3014. ⟨10.1038/s41467-020-16566-1⟩
Formation of amyloid-beta (Aβ) oligomer pores in the membrane of neurons has been proposed to explain neurotoxicity in Alzheimerʼs disease (AD). Here, we present the three-dimensional structure of an Aβ oligomer formed in a membrane mimicking envi
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Scientific Reports
Dipòsit Digital de la UB
Universidad de Barcelona
Scientific Reports
Dipòsit Digital de la UB
Universidad de Barcelona
Peptides are experiencing a new era in medical research, finding applications ranging from therapeutics to vaccines. In spite of the promising properties of peptide pharmaceuticals, their development continues to be hindered by three weaknesses intri
Autor:
Natàlia Carulla, Moeen Meigooni, Jimmy Do, Emad Tajkhorshid, Maxim Mayzel, Benjamin Bardiaux, Sonia Ciudad, Eduard Puig, Sarah Cianférani, Giovanni Maglia, Mariam Bayoumi, Vladislav Yu. Orekhov, Stéphane Chaignepain, Andres S. Arango, Thomas Botzanowski
The formation of amyloid-beta (Aβ) oligomer pores in the membrane of neurons has been proposed as the means to explain neurotoxicity in Alzheimer’s disease (AD). It is therefore critical to characterize Aβ oligomer samples in membrane-mimicking e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f575715ab50208a8bd616a7a2d4125
https://doi.org/10.1101/759472
https://doi.org/10.1101/759472
Autor:
Meritxell Teixidó, Sonia Ciudad, Pol Arranz-Gibert, Roger Prades, Bernat Guixer, Ernest Giralt
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Universidad de Barcelona
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
In recent decades, peptide blood-brain barrier shuttles have emerged as a promising solution for brain drugs that are not able to enter this organ. The research and development of these compounds involve the use of in vitro cell-based models of the B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b87907d3ee102060447b6f0be0c3d354
http://hdl.handle.net/2445/162523
http://hdl.handle.net/2445/162523
Autor:
Marcelo J. Kogan, Bernat Guixer, Eyleen Araya, Roger Prades, Simón Guerrero, Pol Arranz-Gibert, Ernest Giralt, Meritxell Teixidó, Sonia Ciudad
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Dipòsit Digital de la UB
Universidad de Barcelona
Scientific Reports
Dipòsit Digital de la UB
Universidad de Barcelona
Scientific Reports
Low effectiveness and resistance to treatments are commonplace in disorders of the central nervous system (CNS). These issues concern mainly the blood-brain barrier (BBB), which preserves homeostasis in the brain and protects this organ from toxic mo
Autor:
Montserrat, Serra-Batiste, Martí, Ninot-Pedrosa, Eduard, Puig, Sonia, Ciudad, Margarida, Gairí, Natàlia, Carulla
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1779
The formation of amyloid-β peptide (Aβ) oligomers at the cellular membrane is considered a crucial process that underlies neurotoxicity in Alzheimer's disease (AD). To obtain structural information on this type of oligomers, we were inspired by mem
Protein–protein interactions (PPIs) control and regulate most cellular processes, thus offering opportunities for therapeutic intervention. However, the physicochemical features of protein–protein interfaces (large and relatively flat contact pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4c87d0d14a47428cccf407d4c86ff4b
https://doi.org/10.1039/9781788010153-00086
https://doi.org/10.1039/9781788010153-00086
Publikováno v:
Chirality. 25:780-786
In order to define an enantioselective nuclear magnetic resonance (NMR) method for the antiasthmatic drug montelukast, a series of nine easily available products were evaluated as NMR chiral solvating agents (CSAs): D-dibenzoyltartaric acid, D-ditolu
Autor:
Roméo Cecchelli, Meritxell Teixidó, Pol Arranz-Gibert, Sonia Ciudad, Ernest Giralt, Benjamí Oller-Salvia, Roger R. Gomis, Jesús García, Cristina Quintana García, Macarena Sánchez-Navarro, Marc Guiu
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2016, 55 (2), pp.572-575. ⟨10.1002/anie.201508445⟩
Angewandte Chemie (International Ed. in English)
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2016, 55 (2), pp.572-575. ⟨10.1002/anie.201508445⟩
Angewandte Chemie (International Ed. in English)
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
International audience; Drug delivery across the blood-brain barrier (BBB) is a formidable challenge for therapies targeting the central nervous system. Although BBB shuttle peptides enhance transport into the brain non-invasively, their application
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bdc3975308c54a9d2987c809345e778
https://hal-univ-artois.archives-ouvertes.fr/hal-02513287
https://hal-univ-artois.archives-ouvertes.fr/hal-02513287