Zobrazeno 1 - 10
of 316
pro vyhledávání: '"Sonia Caprio"'
Autor:
Michelle Bloyd, Ninet Sinaii, Fabio Rueda Faucz, James Iben, Steven L. Coon, Sonia Caprio, Nicola Santoro, Constantine A. Stratakis, Edra London
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionPediatric obesity has steadily increased in recent decades. Large-scale genome-wide association studies (GWAS) conducted primarily in Eurocentric adult populations have identified approximately 100 loci that predispose to obesity and type
Externí odkaz:
https://doaj.org/article/3c73aefed5704116b3d0233a2c31eb5f
Autor:
Alfonso Galderisi, Domenico Tricò, Jessica Lat, Stephanie Samuels, Ram Weiss, Michelle Van Name, Bridget Pierpont, Nicola Santoro, Sonia Caprio
Publikováno v:
JCI Insight, Vol 8, Iss 22 (2023)
In youths with obesity, the gut hormone potentiation of insulin secretion — the incretin effect — is blunted. We explored the longitudinal impact of the incretin effect during pubertal transition on β cell function and insulin sensitivity. Youth
Externí odkaz:
https://doaj.org/article/0faa652a91af4ee694bbbc1151b547af
Autor:
Seungjin Ryu, Olga Spadaro, Sviatoslav Sidorov, Aileen H. Lee, Sonia Caprio, Christopher Morrison, Steven R. Smith, Eric Ravussin, Irina Shchukina, Maxim N. Artyomov, Yun-Hee Youm, Vishwa Deep Dixit
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
The comprehensive assessment of long-term effects of reducing intake of energy (CALERIE-II; NCT00427193) clinical trial established that caloric restriction (CR) in humans lowers inflammation. The identity and mechanism of endogenous CR-mimetics that
Externí odkaz:
https://doaj.org/article/e954530dc5224073ad8d80f78f968471
Autor:
Kangning Yao, Elena Tarabra, Daniela Sia, Raffaella Morotti, Rima Fawaz, Pamela Valentino, Nicola Santoro, Sonia Caprio, Silvia Liu, Dean Yimlamai
Publikováno v:
Hepatology Communications, Vol 6, Iss 7, Pp 1598-1610 (2022)
Abstract Nonalcoholic fatty liver disease (NAFLD) is the most common type of chronic liver disease in children. The mechanisms that drive NAFLD disease progression in this specific patient population remain poorly defined. In this study, we obtained
Externí odkaz:
https://doaj.org/article/22e27aec548c4908abc02939d059ee8f
Autor:
Brittany Galuppo, Cristiana Agazzi, Bridget Pierpont, Jennifer Chick, Zhongyao Li, Sonia Caprio, Nicola Santoro
Publikováno v:
Nutrition & Diabetes, Vol 12, Iss 1, Pp 1-4 (2022)
Abstract Objective Growth differentiation factor 15 (GDF15) has been associated with food intake and weight regulation in response to metabolic stress. In animal models, it has been noted that it may play a role in the progression of non-alcoholic fa
Externí odkaz:
https://doaj.org/article/202703b945ce4155b611e1087a5f0e99
Autor:
Alfonso Galderisi, Giorgio Perilongo, Sonia Caprio, Liviana Da Dalt, Giovanni Di Salvo, Michela Gatta, Carlo Giaquinto, Rosario Rizzuto, Adelaide Robb, Peter David Sly, Alessandra Simonelli, Annamaria Staiano, Roberto Vettor, Eugenio Baraldi
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
ImportanceThe Padova Chart for Health in Children (PCHC) aims to gather the evidence of healthcare promotion and protection for chidren and adolescents (i.e., aged
Externí odkaz:
https://doaj.org/article/5fb2ff9f04484ba991a119f980614d3e
Autor:
Samantha Simpson, David B. Seifer, Veronika Shabanova, Anna Y. Lynn, Catherine Howe, Erin Rowe, Sonia Caprio, Alla Vash-Margita
Publikováno v:
Reproductive Biology and Endocrinology, Vol 18, Iss 1, Pp 1-9 (2020)
Abstract Background High anti-Müllerian hormone (AMH) levels and 25-hydroxyvitamin D [25(OH)D] deficiency have been associated with polycystic ovarian syndrome (PCOS) in adult women, and implicated in its pathogenesis. Herein we determined if the le
Externí odkaz:
https://doaj.org/article/4991e6417d904ccdbbbae2ab8620e60e
Autor:
Richard D. Khusial, Catherine E. Cioffi, Shelley A. Caltharp, Alyssa M. Krasinskas, Adina Alazraki, Jack Knight‐Scott, Rebecca Cleeton, Eduardo Castillo‐Leon, Dean P. Jones, Bridget Pierpont, Sonia Caprio, Nicola Santoro, Ayman Akil, Miriam B. Vos
Publikováno v:
Hepatology Communications, Vol 3, Iss 10, Pp 1311-1321 (2019)
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in children, but diagnosis is challenging due to limited availability of noninvasive biomarkers. Machine learning applied to high‐resolution metabolomics and clinical
Externí odkaz:
https://doaj.org/article/943afeaca8d442899b6db3dac03fba11
Autor:
Barbara M. Brooks-Worrell, Ashley H. Tjaden, Sharon L. Edelstein, Brenda Palomino, Kristina M. Utzschneider, Silva Arslanian, Kieren J. Mather, Thomas A. Buchanan, Kristen J. Nadeau, Karen Atkinson, Elena Barengolts, Steven E. Kahn, Jerry P. Palmer, The RISE Consortium, David A. Ehrmann, Karla A. Temple, Abby Rue, Babak Mokhlesi, Eve Van Cauter, Susan Sam, M. Annette Miller, Karen M. Atkinson, Tsige Gebremedhin, Abigail Kernan-Schloss, Alexandra Kozedub, Brenda K. Montgomery, Emily J. Morse, Tammy Garrett, Tamara S. Hannon, Amale Lteif, Aniket Patel, Robin Chisholm, Karen Moore, Vivian Pirics, Linda Pratt, Susan Gross, Philip S. Zeitler, Jayne Williams, Melanie Cree-Green, Yesenia Garcia Reyes, Krista Vissat, Silva A. Arslanian, Kathleen Brown, Nancy Guerra, Kristin Porter, Sonia Caprio, Mary Savoye, Bridget Pierpont, Anny H. Xiang, Enrique Trigo, Elizabeth Beale, Ting Chow, Fadi N. Hendee, Namir Katkhouda, Krishan Nayak, Mayra Martinez, Cortney Montgomery, Xinhui Wang, Jun Wu, John M. Lachin, Ashley Hogan Tjaden, Mark T. Tripputi, Santica Marcovina, Jessica Harting, John Albers, Dave Hill, Peter J. Savage, Ellen W. Leschek
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The presence of islet autoantibodies and islet reactive T cells (T+) in adults with established type 2 diabetes (T2D) have been shown to identify those patients with more severe β-cell dysfunction. However, at what stage in the progression toward cl
Externí odkaz:
https://doaj.org/article/27e81150d11d4d01a7eb640383321a97
Autor:
Arvindhan Nagarajan, Max C. Petersen, Ali R. Nasiri, Gina Butrico, Annie Fung, Hai-Bin Ruan, Romy Kursawe, Sonia Caprio, Jacques Thibodeau, Marie-Claude Bourgeois-Daigneault, Lisha Sun, Guangping Gao, Sanjay Bhanot, Michael J. Jurczak, Michael R. Green, Gerald I. Shulman, Narendra Wajapeyee
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Insulin receptor levels at the cell surface are reduced in insulin resistance, for reasons that are not fully understood. Here, the authors identify the E3 ubiquitin ligase MARCH1 as a direct regulator of basal insulin receptor surface levels and, th
Externí odkaz:
https://doaj.org/article/5e20ff02ef4b4bf79837c323cd66c1bb