Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Sonia Brault"'
1
VRQ397 (CRAVKY): a novel noncompetitive V2 receptor antagonist
Autor: François Duhamel, Kaul R, Michel Bouvier, Sonia Brault, Nedev H, Isabelle Lahaie, J-S Joyal, David Hamel, Nikolaus Heveker, Lenka Rihakova, Sylvain Chemtob, Kim Beauregard, Przemyslaw Sapieha, Pierre Hardy, Fernand Gobeil, Xin Hou, Christiane Quiniou, Guillon G, Fadi F. Hamdan, Horacio Uri Saragovi, William D. Lubell, Zhuo Shao
Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 297:R1009-R1018
Vasopressin type 2 receptor (V2R) exhibits mostly important properties for hydroosmotic equilibrium and, to a lesser extent, on vasomotricity. Drugs currently acting on this receptor are analogs of the natural neuropeptide, arginine vasopressin (AVP)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ede014030888a493a6387ba01cb6c9
https://doi.org/10.1152/ajpregu.90766.2008
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2
Lysophosphatidic acid induces endothelial cell death by modulating the redox environment
Autor: Przemyslaw Sapieha, Audrey Fortier, Sylvain Chemtob, Jean-Claude Honoré, Amna Kooli, Alfredo Ribeiro-da-Silva, Daya R. Varma, Pierre Hardy, Sonia Brault, Krishna G. Peri, Pierre Lachapelle, Fernand Gobeil, Elodie Martin, Jean-Sébastien Joyal
Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 292:R1174-R1183
Oxidant stress plays a significant role in hypoxic-ischemic injury to the susceptible microvascular endothelial cells. During oxidant stress, lysophosphatidic acid (LPA) concentrations increase. We explored whether LPA caused cytotoxicity to neuromic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034dcdb95339cfb87d69d057c4e08ce3
https://doi.org/10.1152/ajpregu.00619.2006
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4
Microvascular rarefaction and decreased angiogenesis in rats with fetal programming of hypertension associated with exposure to a low-protein diet in utero
Autor: Gilles Cambonie, Pierre Hardy, K. Bibeau, Isabelle Lahaie, Patrick Pladys, Anne Monique Nuyt, Sonia Brault, Daniella Checchin, Sylvain Chemtob, M. Brochu, G. Thibault, Ngoc Loan Oanh Le, Daniel Abran, Florian Sennlaub
Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 289:R1580-R1588
In hypertension, increased peripheral vascular resistance results from vascular dysfunction with or without structural changes (vessel wall remodeling and/or microvascular rarefaction). Humans with lower birth weight exhibit evidence of vascular dysf
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ffb1230d35f2c2b31338ddff421878d
https://doi.org/10.1152/ajpregu.00031.2005
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5
Isomer-specific contractile effects of a series of synthetic F2-isoprostanes on retinal and cerebral microvasculature
Autor: Sylvain Chemtob, Florian Sennlaub, Kazuo Kanai, Daniel Abran, Daya R. Varma, Sonia Brault, Fernand Gobeil, L. Jackson Roberts, Douglas F. Taber, Xin Hou, Pierre Lachapelle, Daniella Checchin
Publikováno v: Free Radical Biology and Medicine. 36:163-172
F2-isoprostanes (F2-IsoP's) are biologically active prostanoids formed by free radical-mediated peroxidation of arachidonic acid. Four different F2-IsoP regioisomers (5-, 8-, 12-, and 15-series), each comprising eight racemic diastereomers, total 64
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e25bb50e14d50d361ad0f225dfbbb0cf
https://doi.org/10.1016/j.freeradbiomed.2003.10.024
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6
Selective Neuromicrovascular Endothelial Cell Death by 8-Iso-Prostaglandin F 2α
Autor: Daya R. Varma, Anne Marilise Marrache, Xin Hou, Christiane Quiniou, Sylvain Chemtob, Sonia Brault, Fernand Gobeil, Martin Beauchamp, Ana Katherine Martinez-Bermudez, Guillermina Almazan, Jackson Roberts, Christian Lachance
Publikováno v: Stroke. 34:776-782
Background and Purpose— Free radical-induced peroxidation is an important factor in the genesis of hypoxic-ischemic encephalopathy, including that of the preterm infant. Isoprostanes are major peroxidation products. Since microvascular dysfunction
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205d4599843dae989e946f97d866e745
https://doi.org/10.1161/01.str.0000055763.76479.e6
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7
Hypercapnia prevents neovascularization via nitrative stress
Autor: Florian Sennlaub, Michael Balazy, Pierre Hardy, Sonia Brault, Daniella Checchin, Elsa Kermorvant-Duchemin, Sylvain Chemtob, Tang Zhu, Mirna Sirinyan
Publikováno v: Free Radical Biology and Medicine
Free Radical Biology and Medicine, Elsevier, 2006, 40 (3), pp.543-53. ⟨10.1016/j.freeradbiomed.2005.09.016⟩
Free Radical Biology and Medicine, 2006, 40 (3), pp.543-53. ⟨10.1016/j.freeradbiomed.2005.09.016⟩
Neovascularization after an ischemic insult is a beneficial attempt to salvage the injured tissue. Yet, despite the production of angiogenic factors within ischemic tissues, compensatory growth of new vessels fails to provide adequate vascularization
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be4408921378e1525ef2a2ae330d961
https://www.hal.inserm.fr/inserm-00150827
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8
Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration
Autor: Gregor Andelfinger, Chantal J. Boisvert, Elsa Kermorvant-Duchemin, Sonia Brault, Huy Ong, J Russel Falck, Pedro D'Orléans-Juste, Florian Sennlaub, Stéphane Germain, Pierre Hardy, Michael Balazy, Amna Kooli, Fernand Gobeil, Tang Zhu, Kavita Jain, Mirna Sirinyan, Sylvain Chemtob
Publikováno v: Nature Medicine
Nature Medicine, Nature Publishing Group, 2005, 11 (12), pp.1339-45. ⟨10.1038/nm1336⟩
Nature Medicine, 2005, 11 (12), pp.1339-45. ⟨10.1038/nm1336⟩
E K-D and F S contributed equally to this work; Nitrative stress has an important role in microvascular degeneration leading to ischemia in conditions such as diabetic retinopathy and retinopathy of prematurity. Thus far, mediators of nitrative stres
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52e52706c8456cd4d6909207a15ebff
https://www.hal.inserm.fr/inserm-00150825
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9
Dominant role for calpain in thromboxane-induced neuromicrovascular endothelial cytotoxicity
Autor: Pierre Hardy, Amna Kooli, Fernand Gobeil, Florian Sennlaub, Isabelle Lahaie, Alexey V. Pshezhetsky, Martin Beauchamp, Christiane Quiniou, Daniella Checchin, Sonia Brault, Mirna Sirinyan, Sylvain Chemtob
Publikováno v: The Journal of pharmacology and experimental therapeutics. 316(2)
Thromboxane A(2) (TXA(2)) is an important lipid mediator generated during oxidative stress and implicated in ischemic neural injury. This autacoid was recently shown to partake in this injury process by directly inducing endothelial cytotoxicity. We
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdaa2b2cfbe9df7a631ec0782882de19
https://pubmed.ncbi.nlm.nih.gov/16214879
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10
Cytotoxicity of the E(2)-isoprostane 15-E(2t)-IsoP on oligodendrocyte progenitors
Autor: Daya R. Varma, Elsa Kermorvant-Duchemin, Sylvain Chemtob, Guillermina Almazan, Hsueh-Ning Liu, Sonia Brault, Christian Lachance, Qiao-Ling Cui, Gabriela Fragoso, Fernand Gobeil, Ana Katherine Martinez-Bermudez, Christiane Quiniou, Jackson Roberts, Sandy Hemdan
Publikováno v: Free radical biologymedicine. 37(3)
Oxidant stress plays a significant role in the pathogenesis of periventricular leukomalacia (PVL). Isoprostanes (IsoPs) are bioactive products of lipid peroxidation abundantly generated during hypoxic-ischemic injuries. Because loss of oligodendrocyt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca4e8fdafef0ab56cdde995f38d37cb
https://pubmed.ncbi.nlm.nih.gov/15223069
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