Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sonia Boncristiano"'
Autor:
Sonia Boncristiano, Martina Stalder, Esther Kohler, Mathias Jucker, Matthias Staufenbiel, Michelle Pfeifer, Melanie Meyer-Luehmann, Dorothee Abramowski, Paul M. Mathews, Martin C. Herzig, Stephan A. Kaeser, Marc Mercken
Publikováno v:
Nature Neuroscience. 6:370-377
Amyloid precursor protein (APP) processing and the generation of beta-amyloid peptide (Abeta) are important in the pathogenesis of Alzheimer's disease. Although this has been studied extensively at the molecular and cellular levels, much less is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5588fa5c37f16dc5322e7bbc51918b
https://doi.org/10.1038/nn1022
https://doi.org/10.1038/nn1022
Autor:
Luca Bondolfi, Michelle Pfeifer, Peter H. Kelly, Martina Stalder, Sonia Boncristiano, Mathias Jucker, Michael E. Calhoun, Matthias Staufenbiel, Amie L. Phinney, Bernd Sommer, Dorothee Abramowski, Albert Enz, Christine Sturchler-Pierrat
Publikováno v:
The Journal of Neuroscience. 22:3234-3243
Alzheimer's Disease (AD) is a neurodegenerative disorder that is characterized by extracellular deposits of amyloid-beta peptide (Abeta) and a severe depletion of the cholinergic system, although the relationship between these two events is poorly un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a69a891d213f9023d905fa6fab2083
https://doi.org/10.1523/jneurosci.22-08-03234.2002
https://doi.org/10.1523/jneurosci.22-08-03234.2002
Autor:
Luca Bondolfi, Michael E. Calhoun, Karl-Heinz Wiederhold, Mathias Jucker, Sonia Boncristiano, Matthias Staufenbiel, Victor G. Howard, Stephan A. Kaeser
Publikováno v:
Neurobiology of aging. 26(5)
Major pathological findings in Alzheimer's disease (AD) brain include the deposition of amyloid-beta and synapse loss. Synaptic loss has been shown to correlate with the cognitive decline in AD patients, but the relationship between cerebral amyloido
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e13cb4a0e369c182fed0cda87b9d2c9
https://pubmed.ncbi.nlm.nih.gov/15708435
https://pubmed.ncbi.nlm.nih.gov/15708435
Autor:
Martina Stalder, Christine Sturchler-Pierrat, Sonia Boncristiano, Michelle Pfeifer, M C Herzig, Luca Bondolfi, A. Probst, Matthias Staufenbiel, M. E. Calhoun, David T. Winkler, Thomas Deller, A. Phinney, M Tolnay, Mathias Jucker, Karl-Heinz Wiederhold, Bernd Sommer, Dorothee Abramowski
Publikováno v:
Neurodegenerative Disorders: Loss of Function Through Gain of Function ISBN: 9783642074486
Transgenic mice that overexpress mutant human amyloid precursor protein (APP) exhibit one hallmark of Alzheimer’s disease pathology, namely the extracellular deposition of amyloid in plaques and vessels. In an effort to study the impact of cerebral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02d55ca4998561003987bec07afd1276
https://doi.org/10.1007/978-3-662-04399-8_6
https://doi.org/10.1007/978-3-662-04399-8_6
Autor:
Paul M. Mathews, Matthias Staufenbiel, Michelle Pfeifer, Thomas Deller, Sonia Boncristiano, Mathias Jucker, A. Stalder, Luca Bondolfi
Publikováno v:
Science. 298:1379-1379
Immunotherapy for Alzheimer's disease (AD) has been the subject of intense investigation. Both active and passive immunization against β-amyloid peptide (Aβ) in mouse models reduce levels of Aβ, prevent and clear amyloid plaques, and improve cogni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2998cba6802052c86f446af00732e5
https://doi.org/10.1126/science.1078259
https://doi.org/10.1126/science.1078259