Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Sonia Bertrand"'
Autor:
Sylvie Bretin, Caroline Louis, Laure Seguin, Stéphanie Wagner, Jean-Yves Thomas, Sylvie Challal, Nathalie Rogez, Karine Albinet, Fabrice Iop, Nadège Villain, Sonia Bertrand, Ali Krazem, Daniel Bérachochéa, Stéphanie Billiald, Charles Tordjman, Alex Cordi, Daniel Bertrand, Pierre Lestage, Laurence Danober
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184429 (2017)
S 47445 is a novel positive allosteric modulator of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors (AMPA-PAM). S 47445 enhanced glutamate's action at AMPA receptors on human and rat receptors and was inactive at NMDA and k
Externí odkaz:
https://doaj.org/article/921312cb54924540915646f196ad405f
Autor:
Daniel Bertrand, Frances Elmslie, Elaine Hughes, John Trounce, Thomas Sander, Sonia Bertrand, Ortrud K. Steinlein
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 3, Pp 799-804 (2005)
Mutations in nAChRs are found in a rare form of nocturnal frontal lobe epilepsy (ADNFLE). Previously, some nAChR mutations have been described that are associated with additional neurological features such as psychiatric disorders or cognitive defect
Externí odkaz:
https://doaj.org/article/44e0c960763041c58cbf7df05fa4f261
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5597
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic. Although the pathophysiology of SARS-CoV-2 infection is still being elucidated, the nicotinic cholinergic syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c45a3d93935e8da40ec675704e26774
https://doi.org/10.3390/ijms24065597
https://doi.org/10.3390/ijms24065597
Autor:
Lionel Pirsoul, Pierre Mossant, Bruno Mounier, Sonia Bertrand, Marc Maury, Xavier Arnauld de Sartre
Publikováno v:
Natures Sciences Sociétés. 26:223-229
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4e564bcf264c28fff8010a6efc757b3
https://doi.org/10.1051/nss/2018037
https://doi.org/10.1051/nss/2018037
Publikováno v:
Neuropharmacology. 117:422-433
Tropisetron, a 5-HT 3 receptor antagonist commonly prescribed for chemotherapy-induced nausea and vomiting also exhibits high affinity, partial agonist activity at α7 nicotinic acetylcholine receptors (α7 nAChRs). α7 nAChRs are considered viable t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5130c8fc7252cb32986d2fefde0522
https://doi.org/10.1016/j.neuropharm.2017.02.025
https://doi.org/10.1016/j.neuropharm.2017.02.025
Publikováno v:
Helvetica Chimica Acta. 99:790-804
Here we asked the question whether fluorescence labelled small molecule agonists of the α7 nicotinic acetylcholine receptor (nAChR) might be identified to enhance receptor studies. Enantiomerically pure 3-amino-quinuclidines appended with fluorophor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4bdc23ba5fc213d09287677ed2b9fe5
https://doi.org/10.1002/hlca.201600120
https://doi.org/10.1002/hlca.201600120
Autor:
Sonia Bertrand, Laurence Danober, Alain Benoist, Ross Jeggo, Anne-Marie Chollet, Philippe Gloanec, Daniel Bertrand, Jean-Marie Fourquez, Kumiko Kambara
Publikováno v:
Alzheimer's & Dementia. 15:P595-P596
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88a220cdbe14134be0e6f294a7ef36c0
https://doi.org/10.1016/j.jalz.2019.06.2472
https://doi.org/10.1016/j.jalz.2019.06.2472
Autor:
Juan Manuel Viveros-Paredes, Fabrice Marger, Tifany Schaer, Justus J. Bürgi, Jean-Louis Reymond, Daniel Bertrand, Silvan D. Boss, Mahendra Awale, Jürg Gertsch, Sonia Bertrand
Publikováno v:
ACS Chemical Neuroscience
While a plethora of ligands are known for the well studied α7 and α4β2 nicotinic acetylcholine receptor (nAChR), only very few ligands address the related α3β2 nAChR expressed in the central nervous system and at the neuromuscular junction. Star
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730794ef9f947a126bbe49a67d74403f
https://doi.org/10.1021/cn4002297
https://doi.org/10.1021/cn4002297
Autor:
Rebecca J. Howard, Sonia Bertrand, Sergei V. Strelkov, Sarah Debaveye, David A. Weston, Sarah C. R. Lummis, Chris Ulens, Jan Tytgat, Marijke Brams, Daniel Bertrand, Bert Billen, Radovan Spurny, Kerry L. Price
Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry; Vol 288
Journal of Biological Chemistry; Vol 288
Background: Pentameric ligand-gated ion channels are modulated by general anesthetics. Results: The crystal structure of ELIC in complex with bromoform reveals anesthetic binding in the channel pore and in novel sites in the transmembrane and extrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0923dc7169b4f34703d4a4aad7f0b6f6
http://europepmc.org/articles/PMC3605653
http://europepmc.org/articles/PMC3605653
Autor:
Julian Schwartz, Jean-Louis Reymond, Sonia Bertrand, Noemi Garcia-Delgado, Daniel Bertrand, Lise Bréthous
Publikováno v:
Journal of Medicinal Chemistry. 55:4605-4618
The Chemical Universe Generated Databases up to 11 atoms of CNOF (GDB-11) and up to 13 atoms of CNOClS (GDB-13) were used to enumerate analogues of the diamine part of two known α7 nicotinic receptor agonists and construct libraries of virtual analo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32680eb9111bfedd0fb4233e88f252e7
https://doi.org/10.1021/jm300030r
https://doi.org/10.1021/jm300030r