Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sonia Aydin"'
Membrane targeting and secretion of mutant uromodulin in familial juvenile hyperuricemic nephropathy
Autor:
Paul Jennings, Sonia Aydin, Judith Lechner, Sian Williams, Peter Kotanko, Rajesh V. Thakker, Walter Pfaller, Karl Lhotta
Publikováno v:
Journal of the American Society of Nephrology, 18(1), 264-73. American Society of Nephrology
Jennings, P, Aydin, S, Kotanko, P, Lechner, J, Lhotta, K, Williams, S, Thakker, R V & Pfaller, W 2007, ' Membrane targeting and secretion of mutant uromodulin in familial juvenile hyperuricemic nephropathy ', Journal of the American Society of Nephrology, vol. 18, no. 1, pp. 264-73 . https://doi.org/10.1681/ASN.2006020158
Jennings, P, Aydin, S, Kotanko, P, Lechner, J, Lhotta, K, Williams, S, Thakker, R V & Pfaller, W 2007, ' Membrane targeting and secretion of mutant uromodulin in familial juvenile hyperuricemic nephropathy ', Journal of the American Society of Nephrology, vol. 18, no. 1, pp. 264-73 . https://doi.org/10.1681/ASN.2006020158
Familial juvenile hyperuricemic nephropathy (FJHN) is an autosomal dominant genetic disorder that is characterized by hyperuricemia, gout, and tubulointerstitial nephritis. FJHN is caused by mutations in the UMOD gene, which encodes for uromodulin, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b32ce982c6f1c3186732788afeb69a9
https://ora.ox.ac.uk/objects/uuid:ba76f1e9-4301-43f3-82ee-a048892e4d49
https://ora.ox.ac.uk/objects/uuid:ba76f1e9-4301-43f3-82ee-a048892e4d49
Publikováno v:
Toxicology in Vitro
Wilmes, A, Crean, D, Aydin, S, Pfaller, W, Jennings, P & Leonard, M O 2011, ' Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity ', Toxicology in Vitro, vol. 25, no. 3, pp. 613-22 . https://doi.org/10.1016/j.tiv.2010.12.009
Toxicology in Vitro; Vol 25
Toxicology in Vitro, 25(3), 613-22. Elsevier Limited
Wilmes, A, Crean, D, Aydin, S, Pfaller, W, Jennings, P & Leonard, M O 2011, ' Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity ', Toxicology in Vitro, vol. 25, no. 3, pp. 613-22 . https://doi.org/10.1016/j.tiv.2010.12.009
Toxicology in Vitro; Vol 25
Toxicology in Vitro, 25(3), 613-22. Elsevier Limited
The identification and dissection of cellular stress mechanisms is fundamental to understanding the susceptibility of the kidney to chemicals and pharmaceuticals and for the development of renal biomarkers indicative of sub lethal injury. Here, we ut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e60e203bbf186bf2d86fbc814c6363
https://doi.org/10.1016/j.tiv.2010.12.009
https://doi.org/10.1016/j.tiv.2010.12.009
Autor:
Sara Signorelli, Clara Pleban, Walter Pfaller, Sonia Aydin, Thomas Lechleitner, Michael Joannidis, Paul Jennings, Paul Perco
Publikováno v:
American Journal of Physiology : Cell Physiology, 294(2), C543-C554. American Physiological Society
Aydin, S, Signorelli, S, Lechleitner, T, Joannidis, M, Pleban, C, Perco, P, Pfaller, W & Jennings, P 2008, ' Influence of microvascular endothelial cells on transcriptional regulation of proximal tubular epithelial cells ', American Journal of Physiology : Cell Physiology, vol. 294, no. 2, pp. C543-C554 . https://doi.org/10.1152/ajpcell.00307.2007
Aydin, S, Signorelli, S, Lechleitner, T, Joannidis, M, Pleban, C, Perco, P, Pfaller, W & Jennings, P 2008, ' Influence of microvascular endothelial cells on transcriptional regulation of proximal tubular epithelial cells ', American Journal of Physiology : Cell Physiology, vol. 294, no. 2, pp. C543-C554 . https://doi.org/10.1152/ajpcell.00307.2007
In the renal cortex the peritubular capillary network and the proximal tubular epithelium cooperate in solute and water reabsorption, secretion, and inflammation. However, the mechanisms by which these two cell types coordinate such diverse functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956706708df7c764f24c07e5c6cafc70
https://doi.org/10.1152/ajpcell.00307.2007
https://doi.org/10.1152/ajpcell.00307.2007
Autor:
Paul Jennings, Christian Koppelstaetter, Anna Maria Wolf, Gert Mayer, Sonia Aydin, Walter Pfaller, Thomas Abberger
Publikováno v:
American journal of physiology. Renal physiology, 293(3), F831-8. American Physiological Society
Jennings, P, Koppelstaetter, C, Aydin, S, Abberger, T, Wolf, A M, Mayer, G & Pfaller, W 2007, ' Cyclosporine A induces senescence in renal tubular epithelial cells ', American journal of physiology. Renal physiology, vol. 293, no. 3, pp. F831-8 . https://doi.org/10.1152/ajprenal.00005.2007
Jennings, P, Koppelstaetter, C, Aydin, S, Abberger, T, Wolf, A M, Mayer, G & Pfaller, W 2007, ' Cyclosporine A induces senescence in renal tubular epithelial cells ', American journal of physiology. Renal physiology, vol. 293, no. 3, pp. F831-8 . https://doi.org/10.1152/ajprenal.00005.2007
The nephrotoxic potential of the widely used immunosuppressive agent cyclosporine A (CsA) is well recognized. However, the mechanism of renal tubular toxicity is not yet fully elucidated. Chronic CsA nephropathy and renal organ aging share some clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcc385524298996f839a7963f6b87781
https://research.vu.nl/en/publications/e991fb56-b555-4ba6-a27b-3fcf806f5406
https://research.vu.nl/en/publications/e991fb56-b555-4ba6-a27b-3fcf806f5406
Autor:
Paul Jennings, Jordan Kountchev, Sonia Aydin, Daniel H. Sturn, Michael Joannidis, Klaudija Bijuklic, Walter Pfaller, Josef R. Patsch, Julia Hasslacher
Publikováno v:
Bijuklic, K, Jennings, P, Kountchev, J, Hasslacher, J, Aydin, S, Sturn, D, Pfaller, W, Patsch, J R & Joannidis, M 2007, ' Migration of leukocytes across an endothelium-epithelium bilayer as a model of renal interstitial inflammation ', American Journal of Physiology : Cell Physiology, vol. 293, no. 1, pp. C486-92 . https://doi.org/10.1152/ajpcell.00419.2006
American Journal of Physiology : Cell Physiology, 293(1), C486-92. American Physiological Society
American Journal of Physiology : Cell Physiology, 293(1), C486-92. American Physiological Society
Interstitial inflammation has emerged as a key event in the development of acute renal failure. To gain better insight into the nature of these inflammatory processes, the interplay between tubular epithelial cells, endothelial cells, and neutrophils
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74c1c94a09235770f5ef2c13584a41b
https://research.vu.nl/en/publications/6fae0d50-d4e0-490c-bc10-0a4b4133ac49
https://research.vu.nl/en/publications/6fae0d50-d4e0-490c-bc10-0a4b4133ac49