Reconstruction of ancient microbial genomes from the human gut

Autor: Humberto García-Ortiz, Jacob M. Luber, Alexander Hübner, Nicola Segata, Aleksandar Kostic, Marsha C. Wibowo, Angélica Martínez-Hernández, Steven A. LeBlanc, Philipp Kirstahler, Francis E. Smiley, Christina Warinner, Sonia Arora Ballal, Omar Rota-Stabelli, Kun D. Huang, Julia Russ, Richard N. Arnold, Karl J. Reinhard, Sünje Johanna Pamp, Frank Maixner, Lorena Orozco, Samuel Zimmerman, Braden T. Tierney, Cecilia Contreras-Cubas, Francisco Barajas-Olmos, Zhen Yang, Meradeth Snow, Maxime Borry, Tre Blohm

Publikováno v: Wibowo, M C, Yang, Z, Borry, M, Hübner, A, Huang, K D, Tierney, B T, Zimmerman, S, Barajas-Olmos, F, Contreras-Cubas, C, García-Ortiz, H, Martínez-Hernández, A, Luber, J M, Kirstahler, P, Blohm, T, Smiley, F E, Arnold, R, Ballal, S A, Pamp, S J, Russ, J, Maixner, F, Rota-Stabelli, O, Segata, N, Reinhard, K, Orozco, L, Warinner, C, Snow, M, LeBlanc, S & Kostic, A D 2021, ' Reconstruction of ancient microbial genomes from the human gut ', Nature, vol. 594, pp. 234–239 . https://doi.org/10.1038/s41586-021-03532-0
Nature

Loss of gut microbial diversity1–6 in industrial populations is associated with chronic diseases7, underscoring the importance of studying our ancestral gut microbiome. However, relatively little is known about the composition of pre-industrial gut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8d1e4efb4731d9281d80f37b5720c6
https://orbit.dtu.dk/en/publications/e7f12aee-bb87-4996-967e-20ae62b3cc0e

Single-Cell Analyses of Colon and Blood Reveal Distinct Immune Cell Signatures of Ulcerative Colitis and Crohn’s Disease

Autor: Liza Konnikova, Jessica Toothaker, Rima Fawaz, Jared Silverstein, Randi G. Pleskow, Michael Field, Susanna Huh, Beth-Ann Norton, Sabina Sabharwal, Amit S. Grover, Laurie N. Fishman, Peng Liu, Silvana Bonilla, Rachel W. Winter, Jose Ordovas-Montanes, Alex K. Shalek, Punyanganie S. de Silva, Anne A. Wolf, Jodie Ouahed, Bruce H. Horwitz, Sonia Arora Ballal, Victor L. Fox, Frederick L. Makrauer, Marko Vukovic, Sonia Friedman, Leslie S. Kean, Scott B. Snapper, Sarah Wall, Menno Verhave, Leslie M. Higuchi, Athos Bousvaros, Munir Mobassaleh, Stacy A. Kahn, Collin C. McCourt, Jessica R. Allegretti, Naamah L. Zitomersky, Joshua R. Korzenik, Dennis J. Spencer, Alejandro Flores, Vanessa Mitsialis, Jeff Goldsmith, Lori A. Zimmerman, George C. Tseng, Matthew J. Hamilton, Paul A. Rufo, Brian P. Regan, Tamar Parmet, Christine K. Lee

Publikováno v: Gastroenterology

Background & Aims Studies are needed to determine the mechanisms of mucosal dysregulation in patients with inflammatory bowel diseases (IBDs) and differences in inflammatory responses of patients with ulcerative colitis (UC) vs Crohn’s disease (CD)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51f4bc8cfc008667477d4d06c047a1c
https://doi.org/10.1053/j.gastro.2020.04.074

Host lysozyme-mediated lysis of Lactococcus lactis facilitates delivery of colitis-attenuating superoxide dismutase to inflamed colons

Autor: Peggy Garault, Johan E. T. van Hylckama Vlieg, Pascal Courtin, Marie-Pierre Chapot-Chartier, Patrick Veiga, Saulius Kulakauskas, Gaelle Quere, Chloe Beal, Wendy S. Garrett, Jason Kim, Jonathan N. Glickman, Monia Michaud, Sonia Arora Ballal, Kathrin Fenn, Muriel Derrien, Carey Ann Gallini

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America 25 (112), 7803-7808. (2015)

Beneficial microbes that target molecules and pathways, such as oxidative stress, which can negatively affect both host and microbiota, may hold promise as an inflammatory bowel disease therapy. Prior work showed that a five-strain fermented milk pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f93491c84d76cc21463dd413e76469
https://doi.org/10.1073/pnas.1501897112

Ecological robustness of the gut microbiota in response to ingestion of transient food-borne microbes

Autor: Patrick Veiga, Joël Doré, Florence Levenez, Jason Kim, Johan E. T. van Hylckama Vlieg, Peggy Garault, Chenhong Zhang, Rémi Brazeilles, Gaelle Quere, Sonia Arora Ballal, Muriel Derrien, Marie-Christine Degivry, Wendy S. Garrett

Publikováno v: ISME Journal
ISME Journal, Nature Publishing Group, 2016, 10 (9), pp.2235-2245. ⟨10.1038/ismej.2016.13⟩
ISME Journal 9 (10), 2235-2245. (2016)
The ISME Journal

Resident gut microbes co-exist with transient bacteria to form the gut microbiota. Despite increasing evidence suggesting a role for transient microbes on gut microbiota function, the interplay between resident and transient members of this microbial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9403f087451003fa197f9a2df3114737
https://hal.archives-ouvertes.fr/hal-01604968

Sa2016 - Fecal Microbiota Transplantation for Clostridium Difficile in Patients with Inflammatory Bowel Disease; the Pediatric Perspective

Autor: David L. Suskind, Melissa Kennedy, Jess L. Kaplan, Zev Davidovics, Sonia Arora Ballal, Michael Dole, Stacy A. Kahn, Jeffery D. Lewis, Erin Alexander, Mark Bartlett, Jonathan Gisser, Elizabeth Doby, Judith R. Kelsen, Aliza Solomon, Maria Oliva-Hemker, Ashley Lodarek, Steven L. Werlin, Maribeth R. Nicholson, Namita Singh, Tiffany Patton, Karen Queliza, Penny Becker, Suchitra K. Hourigan, Paul Mitchell, Grace Felix, McKenzie Leier, Richard Kellermayer, Michael Docktor, Sonia Michail, Maree Jensen, Sahil Khanna

Publikováno v: Gastroenterology. 154:S-448

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f0a8efd05b94fa9862734f1ff8ff59b
https://doi.org/10.1016/s0016-5085(18)31752-9