Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sonia Al-Qadi"'
Autor:
Eva Villar-Alvarez, Baltazar H. Leal, Raquel Martínez-González, Alberto Pardo, Sonia Al-Qadi, Josué Juárez, Miguel A. Váldez, Adriana Cambón, Silvia Barbosa, Pablo Taboada
Publikováno v:
ACS Omega, Vol 4, Iss 2, Pp 3904-3921 (2019)
Externí odkaz:
https://doaj.org/article/d783e63351aa45f8935a64e9d157c687
Autor:
Miguel A. Valdez, Alberto Pardo, Adriana Cambón, Josué Juárez, Sonia Al-Qadi, Baltazar H. Leal, Eva Villar-Alvarez, Pablo Taboada, Silvia Barbosa, Raquel Martínez-Gonzalez
Publikováno v:
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
ACS Omega, Vol 4, Iss 2, Pp 3904-3921 (2019)
instname
ACS Omega, Vol 4, Iss 2, Pp 3904-3921 (2019)
The ability to specifically silence genes by RNA interference has an enormous potential for treating genetic diseases. However, different drawbacks such as short interfering RNA (siRNA) degradability by serum nucleases and biodistribution issues stil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd28a09d274c0d1a9b14bf2253ad0eb1
https://doi.org/10.1021/acsomega.8b02875
https://doi.org/10.1021/acsomega.8b02875
Publikováno v:
International Journal of Pharmaceutics. 551:23-33
Combined micro- and nanosystems are appealing for pulmonary protein delivery, fulfilling the specific physiological requirements for efficient outcomes in-vivo. However, fabrication of protein formulations may impose stresses perturbing protein confo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::643098afd2d7dbd20904b9249c30fc76
https://doi.org/10.1016/j.ijpharm.2018.08.049
https://doi.org/10.1016/j.ijpharm.2018.08.049
Autor:
Silvia Barbosa, Sonia Al-Qadi, Pablo Taboada, Eva Villar-Alvarez, Adriana Cambón, Baltazar H. Leal, Raquel Martínez-Gonzalez, Alberto Bouzas, Javier Fernández-Vega, Víctor Mosquera, Alberto Pardo
Publikováno v:
Molecular pharmaceutics. 16(8)
The administration of small interfering RNA (siRNA) is a very interesting therapeutic option to treat genetic diseases such as Alzheimer's or some types of cancer, but its effective delivery still remains a challenge. Herein, Au nanorod (GNR)-based p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029a925d49ad1ef94c9e4be2f80efad8
https://pubmed.ncbi.nlm.nih.gov/31188622
https://pubmed.ncbi.nlm.nih.gov/31188622
Autor:
Sonia Al-Qadi, Carmen Remuñán-López, Manuel Alatorre-Meda, Manuel Martín-Pastor, Pablo Taboada
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 141:223-232
The synergistic effects of the polysaccharides chitosan (CS) and hyaluronic acid (HA) formulated into hybrid nanoparticles are promising for drug delivery. In the present work, we performed a detailed analysis of the molecular interactions involved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d0d1022a1627687090f66d35ab6f9b
https://doi.org/10.1016/j.colsurfb.2016.01.029
https://doi.org/10.1016/j.colsurfb.2016.01.029
Autor:
Carmen Remuñán-López, Sonia Al-Qadi
Publikováno v:
Polymer. 55:4012-4021
We herein describe the development of a micro-scale powder containing hybrid polymeric nanoparticles, for pulmonary application. The nanoparticles, composed of chitosan, carboxy methyl-β-cyclodextrin and a gelling counterion, were prepared, by ionot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71e03d28b784545fc99abe8f387443dd
https://doi.org/10.1016/j.polymer.2014.06.046
https://doi.org/10.1016/j.polymer.2014.06.046
Publikováno v:
Chitosan-Based Systems for Biopharmaceuticals: Delivery, Targeting and Polymer Therapeutics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b30bf0b0bf80a2d327e69d7d3586b92
https://doi.org/10.1002/9781119962977.ch11
https://doi.org/10.1002/9781119962977.ch11
Publikováno v:
Journal of Controlled Release. 157:383-390
This work presents a new dry powder system consisting of microencapsulated protein-loaded chitosan nanoparticles (CS NPs). The developed system was evaluated in vivo in rats in order to investigate its potential to transport insulin (INS), a model pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e516f41ebb937a7bd681ae61db76ef0
https://doi.org/10.1016/j.jconrel.2011.08.008
https://doi.org/10.1016/j.jconrel.2011.08.008
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The ability to specifically silence genes using siRNA has enormous potential for treating genetic diseases. However, siRNA instability and biodistribution issues still need to be overcome, and adequate delivery vehicles have proven indispensable in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f89d3ae32fc8de8ef6242957f275ac2
https://doi.org/10.1016/s1773-2247(12)50003-1
https://doi.org/10.1016/s1773-2247(12)50003-1
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The administration of drugs through the pulmonary route offers great advantages, but also requires overcoming many challenges. There is a need to develop appropriate carriers for each active molecule to be delivered to the desired site in the lung, e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2503eec885beedb75dca51e8a2d90f
https://doi.org/10.1016/s1773-2247(10)50004-2
https://doi.org/10.1016/s1773-2247(10)50004-2