Výsledky vyhledávání - "Sonia Agüera-González"

Akademický článek

LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration

Autor: Elvira Infante, Alessia Castagnino, Robin Ferrari, Pedro Monteiro, Sonia Agüera-González, Perrine Paul-Gilloteaux, Mélanie J. Domingues, Paolo Maiuri, Matthew Raab, Catherine M. Shanahan, Alexandre Baffet, Matthieu Piel, Edgar R. Gomes, Philippe Chavrier

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

The ability of cancer cells to migrate through small, constricted areas is limited by nuclear stiffness. Here the authors show that in turn nuclear stiffness stimulates the delivery of enzymes important for the degradation of the extracellular matrix

Externí odkaz: https://doaj.org/article/c03c4d3f6d774108a7eadc5798a2cc80

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Akademický článek

Adenomatous Polyposis Coli Defines Treg Differentiation and Anti-inflammatory Function through Microtubule-Mediated NFAT Localization

Autor: Sonia Agüera-González, Oliver T. Burton, Elena Vázquez-Chávez, Céline Cuche, Floriane Herit, Jérôme Bouchet, Rémi Lasserre, Iratxe del Río-Iñiguez, Vincenzo Di Bartolo, Andrés Alcover

Publikováno v: Cell Reports, Vol 21, Iss 1, Pp 181-194 (2017)

Adenomatous polyposis coli (APC) is a polarity regulator and tumor suppressor associated with familial adenomatous polyposis and colorectal cancer development. Although extensively studied in epithelial transformation, the effect of APC on T lymphocy

Externí odkaz: https://doaj.org/article/5d7f24b8466143de8b5d51999e45a826

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Akademický článek

Group Selection and Contribution of Minority Variants during Virus Adaptation Determines Virus Fitness and Phenotype.

Autor: Antonio V Bordería, Ofer Isakov, Gonzalo Moratorio, Rasmus Henningsson, Sonia Agüera-González, Lindsey Organtini, Nina F Gnädig, Hervé Blanc, Andrés Alcover, Susan Hafenstein, Magnus Fontes, Noam Shomron, Marco Vignuzzi

Publikováno v: PLoS Pathogens, Vol 11, Iss 5, p e1004838 (2015)

Understanding how a pathogen colonizes and adapts to a new host environment is a primary aim in studying emerging infectious diseases. Adaptive mutations arise among the thousands of variants generated during RNA virus infection, and identifying thes

Externí odkaz: https://doaj.org/article/12bf3c4d8949455489cae1b59f70dc80

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Data from Natural Killer Cell Cytotoxicity Is Suppressed by Exposure to the Human NKG2D Ligand MICA*008 That Is Shed by Tumor Cells in Exosomes

Autor: Hugh T. Reyburn, Mar Valés-Gómez, Jeremy N. Skepper, Sonia Agüera-González, Lola Fernández-Messina, Philippe Boutet, Omodele Ashiru

The MHC class I–related chain (MIC) A and MICB ligands for the activating receptor NKG2D can be shed from tumor cells, and the presence of these soluble molecules in sera is related with compromised immune response and progression of disease. Recen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f2f7054eb680aa3606844c58c6d2cc77
https://doi.org/10.1158/0008-5472.c.6500786

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Supplementary Figures 1-3, Table 1 from Natural Killer Cell Cytotoxicity Is Suppressed by Exposure to the Human NKG2D Ligand MICA*008 That Is Shed by Tumor Cells in Exosomes

Autor: Hugh T. Reyburn, Mar Valés-Gómez, Jeremy N. Skepper, Sonia Agüera-González, Lola Fernández-Messina, Philippe Boutet, Omodele Ashiru

Supplementary Figures 1-3, Table 1 from Natural Killer Cell Cytotoxicity Is Suppressed by Exposure to the Human NKG2D Ligand MICA*008 That Is Shed by Tumor Cells in Exosomes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c00b11f69bbd525ce15b2c13571d57
https://doi.org/10.1158/0008-5472.22384148

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Rab11-FIP3 Regulation of Lck Endosomal Traffic Controls TCR Signal Transduction

Autor: Iratxe del Río-Iñiguez, Rémi Lasserre, Sonia Agüera-González, Céline Cuche, Mary W. McCaffrey, Jérôme Bouchet, Elena Vázquez-Chávez, Andrés Alcover, Vincenzo Di Bartolo

Publikováno v: Journal of Immunology
Journal of Immunology, 2017, pp.2967-2978. ⟨10.4049/jimmunol.1600671⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2017, pp.2967-2978. ⟨10.4049/jimmunol.1600671⟩

The role of endosomes in receptor signal transduction is a long-standing question, which remains largely unanswered. The T cell Ag receptor and various components of its proximal signaling machinery are associated with distinct endosomal compartments

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89c6f42b7661b927e4ac4fb7f6ba32e
https://hal-pasteur.archives-ouvertes.fr/pasteur-01519813

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Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T-cell activation

Autor: Vincenzo Di Bartolo, Anne Danckaert, Andrés Alcover, Jérôme Bouchet, Céline Cuche, Iratxe del Río-Iñiguez, Sonia Agüera-González, Mary W. McCaffrey, Rémi Lasserre

Publikováno v: EMBO Journal
EMBO Journal, EMBO Press, 2016, ⟨10.15252/embj.201593274⟩
EMBO Journal, 2016, ⟨10.15252/embj.201593274⟩

International audience; The immunological synapse generation and function is the result of a T-cell polarization process that depends on the orchestrated action of the actin and microtubule cytoskeleton and of intracellu-lar vesicle traffic. However,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56331951d4c32930de949cbe5dc0b69c
https://hal-pasteur.archives-ouvertes.fr/pasteur-01370720/document

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