Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sonia A. Sankovich"'
Autor:
Giuseppe Verdile, Michelle E. Ehrlich, Veer Bala Gupta, Dagmar Ringe, Gregory A. Petsko, Shulin Ju, Renae Barr, Sonia E. Sankovich, Ian Macreadie, Prashant Bharadwaj, Sam Gandy, Joanne M. Caine, M. Lenard Lachenmayer, John W. Steele, Zhenyu Yue, Ralph N. Martins
Publikováno v:
Journal of Alzheimer's Disease. 32:949-967
Latrepirdine (Dimebon), an anti-histamine, has shown some benefits in trials of neurodegenerative diseases characterized by accumulation of aggregated or misfolded protein such as Alzheimer's disease (AD) and has been shown to promote the removal of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79ff35de96d6ee8f4388c79cc7dbbbf
https://doi.org/10.3233/jad-2012-120178
https://doi.org/10.3233/jad-2012-120178
Autor:
Ian Macreadie, Peter I. Macreadie, J.N. Varghese, Lynne J. Waddington, Helma Antony, Jo Caine, Sonia E. Sankovich
Publikováno v:
FEMS Yeast Research. 7:1230-1236
The 42 amino acid Alzheimer's Abeta peptide is involved in the progression of Alzheimer's disease. Here we describe the effects of intracellular Abeta, produced through its attachment to either end of a green fluorescent protein, in yeast. Cells prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4261527f39383d4245fffcc23660d38
https://doi.org/10.1111/j.1567-1364.2007.00285.x
https://doi.org/10.1111/j.1567-1364.2007.00285.x
Autor:
Sonia E. Sankovich, John Mills, Dale A. McPhee, Alison L. Greenway, Ricky W. Johnstone, Paul F. Lambert, Kelly Allen, Gavan Holloway, Ahmed A. Azad
Publikováno v:
Journal of Virology. 76:2692-2702
The nef gene product of human immunodeficiency virus type 1 (HIV-1) is important for the induction of AIDS, and key to its function is its ability to manipulate T-cell function by targeting cellular signal transduction proteins. We reported that Nef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e9217f7d6629cbe88c6c1c152e9f82
https://doi.org/10.1128/jvi.76.6.2692-2702.2002
https://doi.org/10.1128/jvi.76.6.2692-2702.2002
Autor:
Kim Jachno, Leah J. Cosgrove, John D. Bentley, Colin W. Ward, M. J. Frenkel, Peter A. Hoyne, Neil M. McKern, Dean R. Hewish, T. C. Elleman, Sonia E. Sankovich
Publikováno v:
Biochemical Journal. 347:771-779
Site-directed mutagenesis has been used to remove 15 of the 18 potential N-linked glycosylation sites, in 16 combinations, from the human exon 11-minus receptor isoform. The three glycosylation sites not mutated were asparagine residues 25, 397 and 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f29b779d8dd1107378579a82b521241b
https://doi.org/10.1042/bj3470771
https://doi.org/10.1042/bj3470771
Autor:
Janette Berglez, Sonia A. Sankovich, Cyril C. Curtain, Laura A. Castelli, Ian Macreadie, Stuart Smith
Publikováno v:
Biochemical and Biophysical Research Communications. 264:287-290
HIV-1 Vpr is a virion-associated protein that can cause growth arrest when produced inside the cell but when added externally it can cause cell death. Employing the yeast model system, the C-terminal domain, in particular the sequence HFRIGCRHSRIG (V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04493f125729f43dea65278ffa421da
https://doi.org/10.1006/bbrc.1999.1511
https://doi.org/10.1006/bbrc.1999.1511
Autor:
Jonathan B. Baell, Ian Macreadie, Daniela Koleski, Matthews Barry R, Sonia E. Sankovich, Ahmed A. Azad
Publikováno v:
SLAS Discovery. 3:299-304
Viral protein R (Vpr), one of the accessory gene products encoded by the human immunodeficiency virus type 1 (HIV-1) genome, has a number of functions, including causing a growth arrest of HIV-1-in...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14b5c3bad63e6db74b9fd0fa2d0d3c25
https://doi.org/10.1177/108705719800300409
https://doi.org/10.1177/108705719800300409
Autor:
Victor A. Streltsov, Simon James, David L. Paterson, Daryl L. Howard, Jo Caine, Sonia E. Sankovich, Martin D. de Jonge
Publikováno v:
Alzheimer's & Dementia. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70661386823fb7c4f9f46ea4fe2e7136
https://doi.org/10.1016/j.jalz.2012.05.1771
https://doi.org/10.1016/j.jalz.2012.05.1771
Autor:
Sonia E. Sankovich, Anna Lucantoni, Elizabeth V. L. Grgacic, Andrew Wolfe, Ahmed A. Azad, Shomik Sengupta, Chris Mardon, Dean R. Hewish, Ian Macreadie, Dale A. McPhee, Kerri Fuller, Paul Failla, John D. Bentley
Publikováno v:
Scopus-Elsevier
Sequences encoding the 27K and 25K nef gene products (Nef 27 and Nef 25) were amplified by PCR from a human immunodeficiency virus type 1 infectious clone and subcloned directly into Escherichia coli, yeast and baculovirus expression vectors. The yea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6515276a47a74cb9e4d46a6f083b63
https://doi.org/10.1099/0022-1317-75-3-651
https://doi.org/10.1099/0022-1317-75-3-651
Autor:
M. J. Frenkel, V. Chandana Epa, Timothy E. Adams, Elizabeth Da Silva, Peter A. Hoyne, John D. Bentley, Kellie Cartledge, Christine P. Robinson, Meizhen Lou, Colin W. Ward, Violet Stoichevska, T. C. Elleman, Neil M. McKern, George O. Lovrecz, Jennifer L. Lewis, Tam Pham, Ross Fernley, Sonia E. Sankovich, Michael C. Lawrence, Lindsay G. Sparrow, Victor A. Streltsov, Kim M. Richards, Patricia A. Pilling
Publikováno v:
Nature. 443(7108)
The first report of the crystal structure of the whole insulin receptor ectodomain dimer reveals how its multiple domains are organized. The structure also identifies the elusive second binding site on the receptor, and suggests how the high-affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414f6ec25fd18772716ee2d01329667c
https://pubmed.ncbi.nlm.nih.gov/16957736
https://pubmed.ncbi.nlm.nih.gov/16957736
Autor:
Cyril C. Curtain, Laura A. Castelli, Melinda G. Lowe, Ian Macreadie, Sonia E. Sankovich, Ahmed A. Azad, Paul Failla
Publikováno v:
ResearcherID
The Human Immunodeficiency Virus type 1 (HIV-1) Nef protein is essential for AIDS pathogenesis. In order to determine more about the effects of Nef on basic cellular functions Nef was produced in yeast under a variety of conditions and in multiple ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7beeb6271a2606e45e60b4a00a80c8
https://pubmed.ncbi.nlm.nih.gov/9801796
https://pubmed.ncbi.nlm.nih.gov/9801796