Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Sonia A Melo"'
Autor:
Bárbara Adem, Nuno Bastos, Carolina F. Ruivo, Sara Sousa-Alves, Carolina Dias, Patrícia F. Vieira, Inês A. Batista, Bruno Cavadas, Dieter Saur, José C. Machado, Dawen Cai, Sonia A. Melo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC), a lethal disease, requires a grasp of its biology for effective therapies. Exosomes, implicated in cancer, are poorly understood in living systems. Here we use the genetically engineered mouse model (
Externí odkaz:
https://doaj.org/article/bc7d9ee1ccd04333abccf2b19c10a836
Autor:
Nuno Bastos, Stéphanie A. Castaldo, Bárbara Adem, José C. Machado, Carlos A. Melo, Sonia A. Melo
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is expected to soon surpass colorectal cancer as a leading cause of cancer mortality in both males and females in the US, only lagging behind lung cancer. The lethality of PDAC is driven by
Externí odkaz:
https://doaj.org/article/70f87cd2d987494d8ef83b847f5f1b6e
Autor:
Wanderson de Souza, S. Gemini-Piperni, Liliana Grenho, Luís A. Rocha, José M. Granjeiro, Sonia A. Melo, Maria H. Fernandes, Ana R. Ribeiro
Publikováno v:
Biomaterials Science. 11:2427-2444
Titanium implants undergo tribocorrosion processes releasing particles that interact with several cells at the implant–bone interface. Osteoblasts-derived exosomal proteins reduce osteogenic differentiation of HMSCs contributing to joint failure.
Autor:
Isidore Rigoutsos, Sang Kil Lee, Su Youn Nam, Simone Anfossi, Barbara Pasculli, Martin Pichler, Yi Jing, Cristian Rodriguez-Aguayo, Aristeidis G. Telonis, Simona Rossi, Cristina Ivan, Tina Catela Ivkovic, Linda Fabris, Peter M. Clark, Hui Ling, Masayoshi Shimizu, Roxana S. Redis, Maitri Y. Shah, Xinna Zhang, Yoshinaga Okugawa, Eun Jung Jung, Aristotelis Tsirigos, Li Huang, Jana Ferdin, Roberta Gafà, Riccardo Spizzo, Milena S. Nicoloso, Anurag N. Paranjape, Maryam Shariati, Aida Tiron, Jen Jen Yeh, Raul Teruel-Montoya, Lianchun Xiao, Sonia A. Melo, David Menter, Zhi-Qin Jiang, Elsa R. Flores, Massimo Negrini, Ajay Goel, Menashe Bar-Eli, Sendurai A. Mani, Chang Gong Liu, Gabriel Lopez-Berestein, Ioana Berindan-Neagoe, Manel Esteller, Scott Kopetz, Giovanni Lanza, George A. Calin
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-21 (2017)
Abstract Background Non-coding RNAs have been drawing increasing attention in recent years as functional data suggest that they play important roles in key cellular processes. N-BLR is a primate-specific long non-coding RNA that modulates the epithel
Externí odkaz:
https://doaj.org/article/1e8d188da0bf4c3faa5d2b002a7f8760
Autor:
Sonia A. Melo, Linda B. Luecke, Christoph Kahlert, Agustin F. Fernandez, Seth T. Gammon, Judith Kaye, Valerie S. LeBleu, Elizabeth A. Mittendorf, Juergen Weitz, Nuh Rahbari, Christoph Reissfelder, Christian Pilarsky, Mario F. Fraga, David Piwnica-Worms, Raghu Kalluri
Publikováno v:
Nature. 610:E15-E17
Autor:
D. Michiel Pegtel, Nicola Baldini, Tom Wurdinger, Sulev Köks, Katre Maasalu, Aare Martson, Vincenzo Canzonieri, Agostino Steffan, Silvia Cervo, Nicoletta Zini, Tanja D. de Gruijl, Sinead M. Lougheed, Roberta Bonafede, Massimo Dominici, Giulia Grisendi, Monique A.J. van Eijndhoven, Michelina Greco, Laura Roncuzzi, Ekaterina S. Jordanova, Anne-Marie Cleton-Jansen, Sonia A. Melo, Nicolas Léveillé, Xuan Dung Ho, Maria Pérez-Lanzón, Tonny Lagerweij, S. Rubina Baglio
Supplementary figures and legends and supplementary tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f2021d751dee43905d9f797bc462c3
https://doi.org/10.1158/1078-0432.22466991.v1
https://doi.org/10.1158/1078-0432.22466991.v1
Autor:
D. Michiel Pegtel, Nicola Baldini, Tom Wurdinger, Sulev Köks, Katre Maasalu, Aare Martson, Vincenzo Canzonieri, Agostino Steffan, Silvia Cervo, Nicoletta Zini, Tanja D. de Gruijl, Sinead M. Lougheed, Roberta Bonafede, Massimo Dominici, Giulia Grisendi, Monique A.J. van Eijndhoven, Michelina Greco, Laura Roncuzzi, Ekaterina S. Jordanova, Anne-Marie Cleton-Jansen, Sonia A. Melo, Nicolas Léveillé, Xuan Dung Ho, Maria Pérez-Lanzón, Tonny Lagerweij, S. Rubina Baglio
Purpose: Human osteosarcoma is a genetically heterogeneous bone malignancy with poor prognosis despite the employment of aggressive chemotherapy regimens. Because druggable driver mutations have not been established, dissecting the interactions betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06e10495adba46e2af40f470d40a695
https://doi.org/10.1158/1078-0432.c.6526500.v1
https://doi.org/10.1158/1078-0432.c.6526500.v1
Autor:
Carolina F Ruivo, Nuno Bastos, Barbara Adem, Ines Batista, Cecilia Duraes, Carlos A Melo, Stephanie A Castaldo, Francisco Campos‐Laborie, Pedro Moutinho-Ribeiro, Barbara Morão, Ana Costa-Pinto, Soraia Silva, Hugo Osorio, Sergio Ciordia, Jose Luis Costa, David Goodrich, Bruno Cavadas, Luisa Pereira, Tony Kouzarides, Guilherme Macedo, Rui Maio, Fatima Carneiro, Marília Cravo, Raghu Kalluri, Jose Carlos Machado, Sonia A Melo
© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0310b4f559857f08a9f43bab5d8a50c3
https://lirias.kuleuven.be/handle/20.500.12942/707762
https://lirias.kuleuven.be/handle/20.500.12942/707762
Autor:
Pedro Costa-Moreira, Inês A. Batista, Helena Barroca, Marinho Almeida, Joanne Lopes, Fátima Carneiro, Sonia A. Melo, Guilherme Macedo, Bárbara Adem, Pedro Moutinho-Ribeiro
Publikováno v:
Pancreatology. 20:571-575
The clinical management of patients with pancreatic cystic lesions is of utmost importance to identify those at high risk for pathological progression. Current recommendations are guided by clinical presentation and radiologic criteria, but the resul
Autor:
Pedro Moutinho-Ribeiro, Ines A Batista, Sofia T Quintas, Bárbara Adem, Marco Silva, Rui Morais, Armando Peixoto, Rosa Coelho, Pedro Costa-Moreira, Renato Medas, Susana Lopes, Filipe Vilas-Boas, Manuela Baptista, Diogo Dias-Silva, Ana L Esteves, Filipa Martins, Joanne Lopes, Helena Barroca, Fátima Carneiro, Guilherme Macedo, Sonia A Melo
Publikováno v:
World journal of gastroenterology. 28(31)
Individuals within specific risk groups for pancreatic ductal adenocarcinoma (PDAC) [mucinous cystic lesions (MCLs), hereditary risk (HR), and new-late onset diabetes mellitus (NLOD)] represent an opportunity for early cancer detection. Endoscopic ul