Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Sonia, Mediouni"'
Autor:
Wang, Hao, Yuan, Zixuan, Pavel, Mahmud Arif, Jablonski, Sonia Mediouni, Jablonski, Joseph, Hobson, Robert, Valente, Susana, Reddy, Chakravarthy B., Hansen, Scott B.
Publikováno v:
In Journal of Biological Chemistry June 2023 299(6)
Autor:
Zixuan Yuan, Mahmud Arif Pavel, Hao Wang, Jerome C. Kwachukwu, Sonia Mediouni, Joseph Anthony Jablonski, Kendall W. Nettles, Chakravarthy B. Reddy, Susana T. Valente, Scott B. Hansen
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Super-resolution microscopy in cultured cells is employed to dissect the effect of hydroxychloroquine (HCQ) at the plasma membrane and HCQ directly perturbs clustering of the SARS-CoV-2 receptor ACE2 with endocytic lipids and PIP2 clusters.
Externí odkaz:
https://doaj.org/article/da95971dabb642e6b3a7d25f3abd74e0
Autor:
Sonia Mediouni, Huihui Mou, Yuka Otsuka, Joseph Anthony Jablonski, Robert Scott Adcock, Lalit Batra, Dong-Hoon Chung, Christopher Rood, Ian Mitchelle S. de Vera, Ronald Rahaim Jr., Sultan Ullah, Xuerong Yu, Yulia A. Getmanenko, Nicole M. Kennedy, Chao Wang, Tu-Trinh Nguyen, Mitchell Hull, Emily Chen, Thomas D. Bannister, Pierre Baillargeon, Louis Scampavia, Michael Farzan, Susana T. Valente, Timothy P. Spicer
Publikováno v:
SLAS Discovery, Vol 27, Iss 1, Pp 8-19 (2022)
The severe acute respiratory syndrome coronavirus 2 responsible for COVID-19 remains a persistent threat to mankind, especially for the immunocompromised and elderly for which the vaccine may have limited effectiveness. Entry of SARS-CoV-2 requires a
Externí odkaz:
https://doaj.org/article/2347b83126774a29aab28c5d045a7718
Autor:
Zixuan Yuan, Mahmud Arif Pavel, Hao Wang, Jerome C. Kwachukwu, Sonia Mediouni, Joseph Anthony Jablonski, Kendall W. Nettles, Chakravarthy B. Reddy, Susana T. Valente, Scott B. Hansen
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/08b31c7e3eb849eb804d542603f68586
Publikováno v:
Viruses, Vol 14, Iss 9, p 1980 (2022)
Current antiretroviral therapy (ART) increases the survival of HIV-infected individuals, yet it is not curative. The major barrier to finding a definitive cure for HIV is our inability to identify and eliminate long-lived cells containing the dormant
Externí odkaz:
https://doaj.org/article/458c7504fe5d46beb17715ef01c5f0eb
Autor:
Thomas A. Premeaux, Sonia Mediouni, Ana Leda, Robert L. Furler, Susana T. Valente, Howard A. Fine, Douglas F. Nixon, Lishomwa C. Ndhlovu
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Long-term effective use of antiretroviral therapy (ART) among people with HIV (PWH) has significantly reduced the burden of disease, yet a cure for HIV has not been universally achieved, likely due to the persistence of an HIV reservoir. The
Externí odkaz:
https://doaj.org/article/3fe2d372568345668788e4b150413a5e
Autor:
Supriya Swarnkar, Yosef Avchalumov, Isabel Espadas, Eddie Grinman, Xin-an Liu, Bindu L. Raveendra, Aya Zucca, Sonia Mediouni, Abhishek Sadhu, Susana Valente, Damon Page, Kyle Miller, Sathyanarayanan V. Puthanveettil
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109369- (2021)
Summary: Synaptic structural plasticity, key to long-term memory storage, requires translation of localized RNAs delivered by long-distance transport from the neuronal cell body. Mechanisms and regulation of this system remain elusive. Here, we explo
Externí odkaz:
https://doaj.org/article/cee0a12b14c94c2ea5c87730114cff21
Autor:
Guillaume Mousseau, Rachna Aneja, Mark A. Clementz, Sonia Mediouni, Noemia S. Lima, Alexander Haregot, Cari F. Kessing, Joseph A. Jablonski, Suzie Thenin-Houssier, Nisha Nagarsheth, Lydie Trautmann, Susana T. Valente
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) Tat binds the viral RNA structure transactivation-responsive element (TAR) and recruits transcriptional cofactors, amplifying viral mRNA expression. The Tat inhibitor didehydro-cortistatin A (dCA)
Externí odkaz:
https://doaj.org/article/c4b6f2c1a0084651a181b6cce77eddfc
Autor:
Sonia Mediouni, Krishna Chinthalapudi, Mary K. Ekka, Ippei Usui, Joseph A. Jablonski, Mark A. Clementz, Guillaume Mousseau, Jason Nowak, Venkat R. Macherla, Jacob N. Beverage, Eduardo Esquenazi, Phil Baran, Ian Mitchelle S. de Vera, Douglas Kojetin, Erwann P. Loret, Kendall Nettles, Souvik Maiti, Tina Izard, Susana T. Valente
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT The intrinsically disordered HIV-1 Tat protein binds the viral RNA transactivation response structure (TAR), which recruits transcriptional cofactors, amplifying viral mRNA expression. Limited Tat transactivation correlates with HIV-1 latenc
Externí odkaz:
https://doaj.org/article/602de632323a423fab4a3dba4bf5eaf7
Autor:
Hao Wang, Zixuan Yuan, Mahmud Arif Pavel, Sonia Mediouni Jablonski, Joseph Jablonski, Robert Hobson, Susana Valente, Chakravarthy B. Reddy, Scott B. Hansen
Publikováno v:
Journal of Biological Chemistry. :104763
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8f94f0e4309f7ee86461c6d501b5d27
https://doi.org/10.1016/j.jbc.2023.104763
https://doi.org/10.1016/j.jbc.2023.104763