Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Sonia, Kartha"'
Autor:
Sonia Kartha, Christine L. Weisshaar, Ralph A. Pietrofesa, Melpo Christofidou-Solomidou, Beth A. Winkelstein
Publikováno v:
Antioxidants, Vol 9, Iss 12, p 1209 (2020)
Painful cervical radiculopathy is characterized by chronic neuroinflammation that lowers endogenous antioxidant responses leading to the development of oxidative stress and pain after neural trauma. Therefore, antioxidants such as secoisolariciresino
Externí odkaz:
https://doaj.org/article/ac2a92996c7d410b80c6d47bda98a4c1
Autor:
Beth A. Winkelstein, Sonia Kartha, Patrisia De Anda, Alexander M. Benison, Alexander R. Kent, Julia C. Quindlen‐Hotek
Publikováno v:
Neuromodulation
INTRODUCTION: Although nonlinear burst and tonic SCS are believed to treat neuropathic pain via distinct pain pathways, the effectiveness of these modalities on brain activity in vivo has not been investigated. This study compared neuronal firing pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2231f64bb03ca72acf721d73143aab3
https://doi.org/10.1111/ner.13116
https://doi.org/10.1111/ner.13116
Autor:
Ahmad Amirshaghaghi, Sonia Kartha, Lesan Yan, Lijun Luo, Zhiliang Cheng, Beth A. Winkelstein, Meagan E. Ita, Yulong Wei, Andrew Tsourkas
Publikováno v:
ACS Nano. 14:8103-8115
Treating persistent neuropathic pain remains a major clinical challenge. Current conventional treatment approaches carry a substantial risk of toxicity and provide only transient pain relief. In this work, we show that the activity and expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11f1adeef5b4607c81933211e3a91015
https://doi.org/10.1021/acsnano.0c00999
https://doi.org/10.1021/acsnano.0c00999
Publikováno v:
Molecular Pain
Neuropathic injury is accompanied by chronic inflammation contributing to the onset and maintenance of pain after an initial insult. In addition to their roles in promoting immune cell activation, inflammatory mediators like secretory phospholipase A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c1af346dc80f4d2d1e5c3ff9692256a
https://pubmed.ncbi.nlm.nih.gov/34919471
https://pubmed.ncbi.nlm.nih.gov/34919471
Publikováno v:
ACS biomaterials scienceengineering. 3(11)
Neurotrauma is a common source for a host of neurological disorders, including chronic pain. Pathological changes underlying neural injury and pain are complex due to the multiscale spatiotemporal nature of the nervous system and its response to insu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e98a06e1d3dec800c2bedcb3402ad79
https://pubmed.ncbi.nlm.nih.gov/33418699
https://pubmed.ncbi.nlm.nih.gov/33418699
Autor:
Beth A. Winkelstein, Ralph A. Pietrofesa, Melpo Christofidou-Solomidou, Christine L. Weisshaar, Sonia Kartha
Publikováno v:
Antioxidants, Vol 9, Iss 1209, p 1209 (2020)
Antioxidants
Volume 9
Issue 12
Antioxidants
Volume 9
Issue 12
Painful cervical radiculopathy is characterized by chronic neuroinflammation that lowers endogenous antioxidant responses leading to the development of oxidative stress and pain after neural trauma. Therefore, antioxidants such as secoisolariciresino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a681a8447563a7edc599c7bb090bb1
https://www.mdpi.com/2076-3921/9/12/1209
https://www.mdpi.com/2076-3921/9/12/1209
Publikováno v:
Neuroreport
Cervical nerve root injury induces a host of inflammatory mediators in the spinal cord that initiate and maintain neuronal hyperexcitability and pain. Secretory phospholipase A(2) (sPLA(2)) is an enzyme that has been implicated as a mediator of pain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e219bd64ff8793d1792e8ce40f8f3e7
https://europepmc.org/articles/PMC7493813/
https://europepmc.org/articles/PMC7493813/
Autor:
Sonia, Kartha, Lesan, Yan, Meagan E, Ita, Ahmad, Amirshaghaghi, Lijun, Luo, Yulong, Wei, Andrew, Tsourkas, Beth A, Winkelstein, Zhiliang, Cheng
Publikováno v:
ACS Nano
Treating persistent neuropathic pain remains a major clinical challenge. Current conventional treatment approaches carry a substantial risk of toxicity and provide only transient pain relief. In this work, we show that the activity and expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::20a1eb0c8e8fc1c65f53a2dfaa06e480
https://pubmed.ncbi.nlm.nih.gov/32484651
https://pubmed.ncbi.nlm.nih.gov/32484651
Autor:
Rachel L. Welch, Beth A. Winkelstein, Ya-Hsin Yu, Prabesh Ghimire, Megan M. Sperry, Sonia Kartha, Eric J. Granquist
Publikováno v:
J Orthop Res
Mechanical overloading of the temporomandibular joint (TMJ) and biochemical changes, like inflammation and hypoxia, contribute to cartilage degeneration and pain associated with osteoarthritis (OA). Yet, how overloading contributes to early dysregula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24eecf6d1a7bcc3a2ab45f6f2a2d580e
https://europepmc.org/articles/PMC9118642/
https://europepmc.org/articles/PMC9118642/
Publikováno v:
Neuroscience Letters. 655:82-89
The facet joint is a common source of neck pain, particularly after excessive stretch of its capsular ligament. Peptidergic afferents have been shown to have an important role in the development and maintenance of mechanical hyperalgesia, dysregulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ca9245212313ae9cb9eee3af595f25
https://doi.org/10.1016/j.neulet.2017.07.006
https://doi.org/10.1016/j.neulet.2017.07.006