Výsledky vyhledávání - "Sonia, Gasparini"

Akademický článek

Interprofessional education as a potential foundation for future team-based prevention of alcohol use disorder

Autor: Scott Edwards, Tekeda F. Ferguson, Sonia Gasparini, Donald E. Mercante, Patricia E. Molina, Tina P. Gunaldo

Publikováno v: BMC Medical Education, Vol 23, Iss 1, Pp 1-8 (2023)

Abstract Background Effective screening of alcohol use and prevention of alcohol use disorder (AUD) requires the continuous preparation of educated and confident providers across all health professions who will ideally work in close collaboration in

Externí odkaz: https://doaj.org/article/6fcfa740d53d4e90827855ca62dbebb9

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Akademický článek

Cholinergic modulation shifts the response of CA1 pyramidal cells to depolarizing ramps via TRPM4 channels with potential implications for place field firing

Autor: Crescent L Combe, Carol M Upchurch, Carmen C Canavier, Sonia Gasparini

Publikováno v: eLife, Vol 12 (2023)

A synergistic combination of in vitro electrophysiology and multicompartmental modeling of rat CA1 pyramidal neurons identified TRPM4 channels as major drivers of cholinergic modulation of the firing rate during a triangular current ramp, which emula

Externí odkaz: https://doaj.org/article/fcb88f640af74fb18a8c3894c8eee646

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Akademický článek

Topological Regulation of Synaptic AMPA Receptor Expression by the RNA-Binding Protein CPEB3

Autor: Iaroslav Savtchouk, Lu Sun, Crhistian L. Bender, Qian Yang, Gábor Szabó, Sonia Gasparini, Siqiong June Liu

Publikováno v: Cell Reports, Vol 17, Iss 1, Pp 86-103 (2016)

Synaptic receptors gate the neuronal response to incoming signals, but they are not homogeneously distributed on dendrites. A spatially defined receptor distribution can preferentially amplify certain synaptic inputs, resize receptive fields of neuro

Externí odkaz: https://doaj.org/article/be15c1c85e904572888b09c66dc7d871

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Long-Term Inactivation of Sodium Channels as a Mechanism of Adaptation in CA1 Pyramidal Neurons

Autor: Valery Rousseau, Christopher J. Knowlton, Crescent L. Combe, Carmen C. Canavier, Carol Upchurch, Sonia Gasparini

Publikováno v: J Neurosci

Many hippocampal CA1 pyramidal cells function as place cells, increasing their firing rate when a specific place field is traversed. The dependence of CA1 place cell firing on position within the place field is asymmetric. We investigated the source

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde7bf122768fd7ae90e92d870414e5a
https://doi.org/10.1523/jneurosci.1914-21.2022

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Ih from synapses to networks: HCN channel functions and modulation in neurons

Autor: Crescent L. Combe, Sonia Gasparini

Publikováno v: Prog Biophys Mol Biol

Hyperpolarization-activated cyclic nucleotide gated (HCN) channels and the current they carry, Ih, are widely and diversely distributed in the central nervous system (CNS). The distribution of the four subunits of HCN channels is variable within the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf17be42b79f57c98b8458c652b85fc
https://doi.org/10.1016/j.pbiomolbio.2021.06.002

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Akademický článek

Differential Contribution of Ca2+-Dependent Mechanisms to Hyperexcitability in Layer V Neurons of the Medial Entorhinal Cortex

Autor: Eric C. Lin, Crescent L. Combe, Sonia Gasparini

Publikováno v: Frontiers in Cellular Neuroscience, Vol 11 (2017)

Temporal lobe epilepsy is characterized by recurrent seizures in one or both temporal lobes of the brain; some in vitro models show that epileptiform discharges initiate in entorhinal layer V neurons and then spread into other areas of the temporal l

Externí odkaz: https://doaj.org/article/3efa3e735d904d19beb4ffe458e2322f

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