In Vivo Mapping of Myocardial Injury Outside the Infarct Zone: Tissue at an Intermediate Pathological State

Autor: Kaixi Ren, Songwang Hou, Steven E. Johnson, Jon Lomasney, Chad R. Haney, Jungwha Lee, Zhi‐dong Ge, Daniel C. Lee, Jeffrey J. Goldberger, Rishi Arora, Ming Zhao

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)

Background The goal was to determine the feasibility of mapping the injured‐but‐not‐infarcted myocardium using 99mTc‐duramycin in the postischemic heart, with spatial information for its characterization as a pathophysiologically intermediate

Externí odkaz: https://doaj.org/article/c2a59e661d9944878381dd113b2db53e

Anti‐phospholipid antibodies are elevated and functionally active in chronic rhinosinusitis with nasal polyps

Autor: Jacob G. Eide, Jeffanie Wu, Whitney W. Stevens, Junqin Bai, Songwang Hou, Julia H. Huang, Jacob Rosenberg, Paul Utz, Stephanie Shintani‐Smith, David B. Conley, Kevin C. Welch, Robert C. Kern, Kathryn E. Hulse, Anju T. Peters, Leslie C. Grammer, Ming Zhao, Paul Lindholm, Robert P. Schleimer, Bruce K. Tan

Publikováno v: Clinical & Experimental Allergy. 52:954-964

Polyps from patients with chronic rhinosinusitis with nasal polyps (CRSwNP) contain increased levels of autoreactive antibodies, B cells and fibrin deposition. Anti-phospholipid antibodies (APA) are autoantibodies known to cause thrombosis but have n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03127844ed96e136bc94b13d56f235a2
https://doi.org/10.1111/cea.14120

The K-Ras effector p38γ MAPK confers intrinsic resistance to tyrosine kinase inhibitors by stimulating EGFR transcription and EGFR dephosphorylation

Autor: Xiaomei Qi, Songwang Hou, Matthew Mortensen, Guan Chen, Charles R. Myers, Adrienne Lepp, Ning Yin, Yongsheng Ji

Publikováno v: Journal of Biological Chemistry. 292:15070-15079

Mutations in K-Ras and epidermal growth factor receptor (EGFR) are mutually exclusive, but it is not known how K-Ras activation inactivates EGFR, leading to resistance of cancer cells to anti-EGFR therapy. Here, we report that the K-Ras effector p38�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f43f3c565119e05d21cc5ace995e798
https://doi.org/10.1074/jbc.m117.779488

Early endosome as a pathogenic target for antiphosphatidylethanolamine antibodies

Autor: Ke Ke, Songwang Hou, Ming Zhao, Rosalind Ramsey-Goldman, Heike Fölsch, Joan Cook Mills

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 114(52)

Phosphatidylethanolamine (PE) is a major phospholipid species with important roles in membrane trafficking and reorganization. Accumulating clinical data indicate that the presence of circulating antibodies against PE is positively correlated with th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15cb7a38a5f46155dcc98e8ae5f5bd4f
https://pubmed.ncbi.nlm.nih.gov/29229837

The outcome of ELISA for antiphosphatidylethanolamine antibodies is dependent on the composition of phosphatidylethanolamine

Autor: Ming Zhao, Paul E. Harper, Songwang Hou, Nathalie Bardin

Publikováno v: Journal of Immunological Methods
Journal of Immunological Methods, Elsevier, 2017, pp.27-34
Journal of Immunological Methods, 2017, pp.27-34

The presence of circulating autoantibodies against phosphatidylethanolamine (PE) has been shown to be positively associated with symptoms of antiphospholipid syndromes (APS). However, the current ELISA-based tests for antiphosphatidylethanolamine (aP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d763117b7559dc8d3ecd687226215de
https://hal-amu.archives-ouvertes.fr/hal-01465052