Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Songsen Fu"'
Publikováno v:
Open Biology, Vol 13, Iss 1 (2023)
The phosphorylation of nucleosides and their polymerization are crucial issues concerning the origin of life. The question of how these plausible chemical processes took place in the prebiotic Earth is still perplexing, despite several studies that h
Externí odkaz:
https://doaj.org/article/be08242366144863bd5bea18dc889d8a
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7332 (2023)
Amino acid (AA) analysis is important in biochemistry, food science, and clinical medicine. However, due to intrinsic limitations, AAs usually require derivatization to improve their separation and determination. Here, we present a liquid chromatogra
Externí odkaz:
https://doaj.org/article/8c36593a085a4af094ace7924ca2ec0a
Autor:
Songsen Fu, Fulai Li, Biling Huang, Huahuan Cai, Feng Ni, Jianxi Ying, Yan Liu, Chuan Fu, Xiang Gao, Yanmei Li, Yufen Zhao
Publikováno v:
SCIENTIA SINICA Chimica. 53:338-348
Publikováno v:
Briefings in Bioinformatics. 24
Protein phosphorylation, one of the main protein post-translational modifications, is required for regulating various life activities. Kinases and phosphatases that regulate protein phosphorylation in humans have been targeted to treat various diseas
Publikováno v:
Earth and Planetary Science Letters. 607:118072
Autor:
Jia Qin, Qinglian Liu, Songsen Fu, Qi Chang, Qianbin Li, Zhuo Chen, Gaoyun Hu, Lijun Li, Xiaohui Li, Liqing Hu
Publikováno v:
Journal of Medicinal Chemistry. 63:11215-11234
Current pulmonary arterial hypertension (PAH) therapeutic strategies mainly focus on vascular relaxation with less emphasis on vascular remodeling, which results in poor prognosis. Hence, dual pathway regulators with vasodilation effect via soluble g
Photoaffinity probes combined with the chemical proteomic platform have emerged as versatile tools for ligand and target discovery. However, photoaffinity probes with retained activity cannot always label the known target, indicating that it is chall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e282fb2c84afd7268af2dee486fe8b8
https://doi.org/10.26434/chemrxiv-2021-9rngz-v2
https://doi.org/10.26434/chemrxiv-2021-9rngz-v2
Publikováno v:
Computers in Biology and Medicine. 151:106280
Phosphorylation plays a key role in the regulation of protein function. In addition to the extensively studied O-phosphorylation of serine, threonine, and tyrosine, emerging evidence suggests that the non-canonical phosphorylation of histidine, lysin
Publikováno v:
Rapid communications in mass spectrometry : RCMREFERENCES. 35(22)
RATIONALE Compared with phosphorylation of arginine and histidine, the study of phosphorylation of lysine lags far behind. The major challenges toward the current study of phosphorylation of lysine include synthesis and unambiguous phosphosite identi