Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Songlei, Li"'
Autor:
Jason G, Kettle, Sharan K, Bagal, Sue, Bickerton, Michael S, Bodnarchuk, Jason, Breed, Rodrigo J, Carbajo, Doyle J, Cassar, Atanu, Chakraborty, Sabina, Cosulich, Iain, Cumming, Michael, Davies, Andrew, Eatherton, Laura, Evans, Lyman, Feron, Shaun, Fillery, Emma S, Gleave, Frederick W, Goldberg, Stephanie, Harlfinger, Lyndsey, Hanson, Martin, Howard, Rachel, Howells, Anne, Jackson, Paul, Kemmitt, Jennifer K, Kingston, Scott, Lamont, Hilary J, Lewis, Songlei, Li, Libin, Liu, Derek, Ogg, Christopher, Phillips, Radek, Polanski, Graeme, Robb, David, Robinson, Sarah, Ross, James M, Smith, Michael, Tonge, Rebecca, Whiteley, Junsheng, Yang, Longfei, Zhang, Xiliang, Zhao
Publikováno v:
Journal of medicinal chemistry. 63(9)
Attempts to directly drug the important oncogene KRAS have met with limited success despite numerous efforts across industry and academia. The KRAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26cfa402e109914535c92b373ce688b5
https://pubmed.ncbi.nlm.nih.gov/32023060
https://pubmed.ncbi.nlm.nih.gov/32023060
Publikováno v:
Journal of the American Chemical Society. 138:12956-12962
Inspired by the zwitterion species generated from the splitting of H2 by frustrated Lewis pairs, we put forward a novel frustrated Lewis pair by the combination of Hδ- and Hδ+ incorporated Lewis acid and base together. Piers’ borane and chiral te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8149aa6550aafb6c22f2cbd78d72eea2
https://doi.org/10.1021/jacs.6b07245
https://doi.org/10.1021/jacs.6b07245
Publikováno v:
Organic letters. 19(10)
An asymmetric transfer hydrogenation of 2,3-disubstituted quinoxalines using a chiral frustrated Lewis pair of Piers’ borane and (R)-tert-butylsulfinamide as the catalyst with ammonia borane as the hydrogen source has been successfully realized. Fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d642a54f41ca889e6b2ca8f5debaa1
https://pubmed.ncbi.nlm.nih.gov/28459591
https://pubmed.ncbi.nlm.nih.gov/28459591
Publikováno v:
Organic Letters. 14:5270-5273
An efficient asymmetric biomimetic transamination of α-keto esters with quinine derivatives as chiral bases was described. A wide variety of α-amino esters containing various functional groups can be synthesized in high yield and enantioselectivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e472801688b09a168f52fb4a17c84c99
https://doi.org/10.1021/ol302427d
https://doi.org/10.1021/ol302427d
Publikováno v:
ChemInform. 44
An asymmetric biomimetic transamination of aromatic ketones to optically active amines with o-HOPhCH2NH2 as amine source catalyzed by hydroquinine-derived chiral base is described. Up to 85% ee was obtained.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8d15d1f0e446f025f7ef39adccc1ac5
https://doi.org/10.1002/chin.201319036
https://doi.org/10.1002/chin.201319036
Publikováno v:
ChemInform. 44
It is found that the chiral bases (QUI) and (ALK) efficiently promote the asymmetric transamination of α-keto esters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae78a8a132ea9c0b582c68e7f3c1e420
https://doi.org/10.1002/chin.201310049
https://doi.org/10.1002/chin.201310049
Publikováno v:
Organicbiomolecular chemistry. 10(45)
An asymmetric biomimetic transamination of aromatic ketones to optically active amines with o-HOPhCH(2)NH(2) as amine source catalyzed by hydroquinine-derived chiral base is described. Up to 85% ee was obtained.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ba518f427fe26a051b5d95e6216e26
https://pubmed.ncbi.nlm.nih.gov/23086578
https://pubmed.ncbi.nlm.nih.gov/23086578
Publikováno v:
Organic letters. 13(21)
A strategy to construct the hexacyclic skeleton of trigonoliimines A, B and their derivatives involving a carbanion-triggered intramolecular cyclization of a seven-membered ring and a subsequent six-membered ring formation in one pot is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4dd3b60144390b2d199896d686662d
https://pubmed.ncbi.nlm.nih.gov/21988530
https://pubmed.ncbi.nlm.nih.gov/21988530
Publikováno v:
Journal of the American Chemical Society; 10/5/2016, Vol. 138 Issue 39, p12956-12962, 7p
Publikováno v:
Organic Letters; Nov2011, Vol. 13 Issue 21, p5827-5829, 3p