Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Songila M.S.R. Doi"'
Publikováno v:
Journal of visualized experiments : JoVE. (143)
Dominant-negative (DN) protein inhibition is a powerful method to manipulate protein function and offers several advantages over other genome-based approaches. For example, although chimeric and Cre-LoxP targeting strategies have been widely used, th
Autor:
Shikha Tarang, Donald W. Harms, Songila M.S.R. Doi, Channabasavaiah B. Gurumurthy, Rolen M. Quadros, Sonia M. Rocha-Sanchez
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 9 (2015)
Frontiers in Cellular Neuroscience, Vol 9 (2015)
Retinoblastoma 1 (Rb1) is an essential gene regulating cellular proliferation, differentiation, and homeostasis. To exert these functions, Rb1 is recruited and physically interacts with a growing variety of signaling pathways. While Rb1 does not appe