Association between BDNF rs6265 polymorphisms and postoperative cognitive dysfunction in Chinese Han Population

Autor: Songhui Xie, Lu Yu, Mingming Zhou, Li Liu, Daoyun Lei, Chao Han

Publikováno v: Brain and Behavior, Vol 10, Iss 10, Pp n/a-n/a (2020)

Abstract Introduction Brain‐derived neurotrophic factor (BDNF) plays a critical role in the pathogenesis of postoperative cognitive dysfunction (POCD). In present study, we aimed to assess the possible association between POCD and BDNF rs6265 polym

Externí odkaz: https://doaj.org/article/3549e866a3294eb9865f88aabea4804b

Preoperative anxiety induces chronic postoperative pain by activating astrocytes in the anterior cingulate cortex region

Autor: Damin Gu, Minmin Zhou, Chao Han, Daoyun Lei, Songhui Xie, Yanbo Yuan, Tieliang Ma

Publikováno v: Revista da Associação Médica Brasileira v.65 n.9 2019
Revista da Associação Médica Brasileira
Associação Médica Brasileira (AMB)
instacron:AMB
Revista da Associação Médica Brasileira, Vol 65, Iss 9, Pp 1174-1180 (2019)

SUMMARY OBJECTIVE The study aims to explore the relationship between preoperative anxiety and chronic postoperative pain. METHODS A total of forty rats were divided into four groups, control, single-prolonged stress alone, Hysterectomy alone, and SPS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57982fc833f9ff01631a1ade3c433b7
https://doi.org/10.1590/1806-9282.65.9.1174

Dexmedetomidine Directs T Helper Cells toward Th1 Cell Differentiation via the STAT1-T-Bet Pathway

Autor: Chao Han, Songhui Xie, Tieliang Ma, Daoyun Lei, Yanxing Guo, Li Liu, Haiyan Ji

Publikováno v: BioMed Research International, Vol 2021 (2021)
BioMed Research International

Dexmedetomidine is an α2 adrenergic receptor agonist that has been reported to modulate the polarization of CD4+ T cells. However, the underlying mechanisms by which dexmedetomidine induces T-helper 1 (Th1) cell differentiation remain poorly underst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676141e91419618bb763dbca9e07e12e
https://doaj.org/article/7f6ec498754e49538016d2af8fd1a6c9

Association between BDNF rs6265 polymorphisms and postoperative cognitive dysfunction in Chinese Han Population

Autor: Mingming Zhou, Daoyun Lei, Lu Yu, Chao Han, Songhui Xie, Li Liu

Publikováno v: Brain and Behavior, Vol 10, Iss 10, Pp n/a-n/a (2020)
Brain and Behavior

Introduction Brain‐derived neurotrophic factor (BDNF) plays a critical role in the pathogenesis of postoperative cognitive dysfunction (POCD). In present study, we aimed to assess the possible association between POCD and BDNF rs6265 polymorphisms.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::765af0dd60c8ba3cfa8c5575675b4a52
https://pubmed.ncbi.nlm.nih.gov/33405375

Dexmedetomidine May Reduce IL-6 Level and the Risk of Postoperative Cognitive Dysfunction in Patients After Surgery: A Meta-Analysis

Autor: Yeqin Sha, Songhui Xie, Li Liu, Daoyun Lei, Chao Han, Shuang Wen

Publikováno v: Dose-Response, Vol 18 (2020)
Dose-Response

Dexmedetomidine (DEX) was widely used in clinical work. However, the effectiveness of DEX on postoperative cognitive dysfunction (POCD) was still need to be confirmed. The aim of this meta-analysis was to explore whether DEX can reduce the incidence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ddd5e52668481ef40a40873fe3bd8e
https://doi.org/10.1177/1559325820902345