Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Songhai Chen"'
Autor:
Ang Huang, Cailun Zou, Zhe Dai, Ying Sun, Jing Wang, Shuhong Liu, Lin Han, Songhai Chen, Qingsheng Liang, Chunyan Wang, Yingjie Zhuang, Tong Dang, Binxia Chang, Yijin Wang, Zhengsheng Zou
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundIt is unclear whether patients with metabolic dysfunction-associated steatotic liver disease (MASLD) are allowed variable low levels of alcohol. This study aimed to evaluate the effect of mild-moderate alcohol consumption on the biochemical
Externí odkaz:
https://doaj.org/article/5dee66e152f048b580d360d8b6d8d4cf
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
GPCRs are highly desirable drug targets for human disease. Although GPCR dysfunction drives development and progression of many tumors, including breast cancer (BC), targeting individual GPCRs has limited efficacy as a cancer therapy because numerous
Externí odkaz:
https://doaj.org/article/e847b129bf434051bc84d8e6abd7ee2b
Autor:
Lin Han, Ang Huang, Jinjun Chen, Guangju Teng, Ying Sun, Binxia Chang, Hong-Li Liu, Manman Xu, Xiaoqin Lan, Qingsheng Liang, Jun Zhao, Hui Tian, Songhai Chen, Yun Zhu, Huan Xie, Tong Dang, Jing Wang, Ning Li, Xiaoxia Wang, Yu Chen, Yong-Feng Yang, Dong Ji, Zhengsheng Zou
Publikováno v:
Hepatology International.
Background There is growing recognition of natural history, complications, and outcomes of patients who develop non-acetaminophen (APAP) drug-induced acute liver failure (ALF). To clarify high-risk factors and develop a nomogram model to predict tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cfb2353749d7b52abb01b0cd5bddb5c
https://doi.org/10.1007/s12072-023-10541-w
https://doi.org/10.1007/s12072-023-10541-w
Autor:
Dawn E. Quelle, Michael D. Henry, Steven R. Grossman, J. Nathan Davis, Shari Meyers, David K. Meyerholz, Joseph J. Cullen, Kokou D. Zamba, Songhai Chen, Xiaoyun Tang, Xuefeng Zhang, Seema Paliwal, J. Matthew Barnes, Viviane Palhares Muniz
Pancreatic ductal adenocarcinoma (PDAC) is an incurable, highly metastatic disease that is largely resistant to existing treatments. A better understanding of the genetic basis of PDAC metastasis should facilitate development of improved therapies. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af3e80f03f2ca5eb99738ef4a5c2e78
https://doi.org/10.1158/1541-7786.c.6542334
https://doi.org/10.1158/1541-7786.c.6542334
Constitutively active mutations in the Gαi2and GαoAsubunits of heterotrimeric G proteins have been identified in several human cancers including breast cancer, but their functional significance in tumorigenesis and metastasis has not been well char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7edbd4d7edc671f0a581bfb752170d9
https://doi.org/10.1101/2023.01.16.524334
https://doi.org/10.1101/2023.01.16.524334
Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1719
SummaryCancer stem cells (CSCs) are a small subpopulation of cells within tumors that are resistant to anti-tumor therapies, making them a likely origin of tumor relapse after treatment. In many cancers including breast cancer, CSC function is regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f59e6539586da8917519462ed4edc3
https://doi.org/10.1101/2022.02.05.479272
https://doi.org/10.1101/2022.02.05.479272
Publikováno v:
Journal of Oncology.
Hepatocellular carcinoma (HCC) is a highly aggressive malignant disease, and numerous studies have shown that certain functional long noncoding RNAs (lncRNAs) are implicated in the progression of several cancers. The purpose of the research was to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88cac36a4c93cdb92ddb4971cd2fd5ca
Autor:
Fang Lin, Juan J Rodriguez, Saeb Suhaib, Anurag Kakkerla Balaraju, Nhan T Nguyen, Heston Steen, Bo Hu, Yuanyuan Gao, Songhai Chen
Publikováno v:
Journal of Cell Biology. 220
Glypicans influence signaling pathways by regulating morphogen trafficking and reception. However, the underlying mechanisms in vertebrates are poorly understood. In zebrafish, Glypican 4 (Gpc4) is required for convergence and extension (C&E) of both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4de8e08dc8f5f69f53800cf964a61a
https://doi.org/10.1083/jcb.202009082
https://doi.org/10.1083/jcb.202009082
Publikováno v:
JCI Insight
GPCRs are highly desirable drug targets for human disease. Although GPCR dysfunction drives development and progression of many tumors, including breast cancer (BC), targeting individual GPCRs has limited efficacy as a cancer therapy because numerous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97aa3114bdb147da1283afa398007c0f
https://doi.org/10.1172/jci.insight.150532
https://doi.org/10.1172/jci.insight.150532
G protein coupled receptors (GPCRs) are among the most desirable drug targets for human disease. Although GPCR dysfunction drives the development and progression of many tumors including breast cancer (BC), targeting individual GPCRs has limited effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db838b1ada6f75db9669c99558e85350
https://doi.org/10.1101/2021.06.15.448534
https://doi.org/10.1101/2021.06.15.448534