Nedd4-2–dependent Ubiquitination Potentiates the Inhibition of Human NHE3 by Cholera Toxin and Enteropathogenic Escherichia coliSummary

Autor: Kayte A. Jenkin, Yiran Han, Songbai Lin, Peijian He, C. Chris Yun

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 695-716 (2022)

Background & Aims: Diarrhea is one of the most common illnesses and is often caused by bacterial infection. Recently, we have shown that human Na+/H+ exchanger NHE3 (hNHE3), but not non-human NHE3s, interacts with the E3 ubiquitin ligase Nedd4-2. We

Externí odkaz: https://doaj.org/article/311867a552d84d178a25a8b1d43ff2d4

Fatal myositis and spontaneous haematoma induced by combined immune checkpoint inhibitor treatment in a patient with pancreatic adenocarcinoma

Autor: Yuan Liu, Zhi Liu, Xuejun Zeng, Chunmei Bai, Lin Chen, Songbai Lin, Xinlun Tian

Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-5 (2019)

Abstract Background Immune checkpoint inhibitors (ICIs) have achieved unprecedented success in cancer treatment over the past decade. The application of ICIs hasled to the discovery of various types of immune-related adverse events (irAEs). Here, we

Externí odkaz: https://doaj.org/article/bb96fd0bd0fe442baf17d05def8d8976

Development of a unique small molecule modulator of CXCR4.

Autor: Zhongxing Liang, Weiqiang Zhan, Aizhi Zhu, Younghyoun Yoon, Songbai Lin, Maiko Sasaki, Jan-Michael A Klapproth, Hua Yang, Hans E Grossniklaus, Jianguo Xu, Mauricio Rojas, Ronald J Voll, Mark M Goodman, Richard F Arrendale, Jin Liu, C Chris Yun, James P Snyder, Dennis C Liotta, Hyunsuk Shim

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e34038 (2012)

Metastasis, the spread and growth of tumor cells to distant organ sites, represents the most devastating attribute and plays a major role in the morbidity and mortality of cancer. Inflammation is crucial for malignant tumor transformation and surviva

Externí odkaz: https://doaj.org/article/56ba1df1025349fea67ceff4c086a48d

Nedd4-2–dependent Ubiquitination Potentiates the Inhibition of Human NHE3 by Cholera Toxin and Enteropathogenic Escherichia coli

Autor: C. Chris Yun, Yiran Han, Songbai Lin, Peijian He, Kayte A. Jenkin

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 695-716 (2022)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Diarrhea is one of the most common illnesses and is often caused by bacterial infection. Recently, we have shown that human Na+/H+ exchanger NHE3 (hNHE3), but not non-human NHE3s, interacts with the E3 ubiquitin ligase Nedd4-2. We h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d39e72e4258b61df22d22d51d780ec
https://doi.org/10.1016/j.jcmgh.2021.11.006

Predicting Diabetes in Patients with Metabolic Syndrome Using Machine-Learning Model Based on Multiple Years' Data

Autor: Jing Li, Zheng Xu, Tengda Xu, Songbai Lin

Publikováno v: Diabetes, metabolic syndrome and obesity : targets and therapy. 15

Jing Li1 *, Zheng Xu2 *, Tengda Xu,1 Songbai Lin1 1Department of Health Management, Peking Union Medical College Hospital, Beijing, People’s Republic of China; 2Department of AI Research, Digital Health China Technologies Co. Ltd, Beijin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b1246de47435459aed42f44141d034
https://pubmed.ncbi.nlm.nih.gov/36186938