Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Song-yi Yao"'
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152163 (2016)
BACKGROUND:Impaired remyelination of demyelinated axons is a major cause of neurological disability. In inflammatory demyelinating disease of the central nervous system (CNS), although remyelination does happen, it is often incomplete, resulting in p
Externí odkaz:
https://doaj.org/article/74a924dc3793420b944b1414eada391f
Autor:
Natarajan, Chandramohan1, Song-Yi Yao1, Sriram, Subramaniam1 subramaniam.sriram@vanderbilt.edu
Publikováno v:
PLoS ONE. 3/29/2016, Vol. 11 Issue 3, p1-24. 24p.
Autor:
Yi-Wei Tang, Subramaniam Sriram, Haijing Li, Song-yi Yao, Shufang Meng, William M Mitchell, Charles W Stratton
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5200 (2009)
A standardized molecular test for the detection of Chlamydophila pneumoniae DNA in cerebrospinal fluid (CSF) would assist the further assessment of the association of C. pneumoniae with multiple sclerosis (MS). We developed and validated a qualitativ
Externí odkaz:
https://doaj.org/article/ee00ddbd4f0e4b299252b62cdadbac94
Publikováno v:
Glia. 61:1261-1273
We examined the phenotypic composition of cells and the underlying mechanisms of demyelination following injection of lipopolysaccharide (LPS) into the corpus callosum of rats. Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assa
Publikováno v:
Mitochondrion. 12:336-344
Products of inflammation and the activation of nitric oxide synthase have been proposed as a mechanism of oligodendrocyte injury in CNS inflammation. There are currently three well described and known isoforms of NOS. Of these, neuronal NOS (nNOS) wa
Publikováno v:
Journal of Neuroscience Research. 86:2403-2413
Hypoxia-inducible factor-1alpha (HIF-1alpha) is a transcription factor induced under hypoxic conditions. HIF-1alpha promotes the expression of genes encoding proteins that increase the cellular supply of oxygen and promote survival in periods of cell
Publikováno v:
Journal of Neuroimmunology. 200:17-26
We examined the effect of lipopolysaccharide (LPS) or lipotechoic acid (LTA) on the regulation of hypoxia inducible factor (HIF-1) alpha on the MO3.13 cells, a human oligodendroglial cell line . Our study shows that MO3.13 cells express the toll like
Publikováno v:
The Journal of Infectious Diseases. 192:1219-1228
To examine a possible relationship between Chlamydia pneumoniae infection and multiple sclerosis (MS), we undertook an immunohistochemical (IHC), molecular, and ultrastructural comparison of central nervous system (CNS) tissue and cerebrospinal fluid
Publikováno v:
The Journal of Experimental Medicine
Experimental allergic encephalitis (EAE) is considered by many to be a model for human multiple sclerosis. Intraperitoneal inoculation of mice with Chlamydia pneumoniae, after immunization with neural antigens, increased the severity of EAE. Accentua
Autor:
Subramaniam Sriram, John T. Tossberg, Thomas M. Aune, Song-Yi Yao, Charles F. Spurlock, Fanglin Zhang
Publikováno v:
Annals of Clinical and Translational Neurology
Objective We examined the expression of IL-33 as an indicator of an innate immune response in relapsing remitting MS (RRMS) and controls. We proposed a link between the expression of IL-33 and IL-33 regulated genes to histone deacetylase (HDAC) activ