Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Song-Qi Gao"'
Autor:
Da Sun, Wenyu Sun, Song-Qi Gao, Jonathan Lehrer, Amirreza Naderi, Cheng Wei, Sangjoon Lee, Andrew L. Schilb, Josef Scheidt, Ryan C. Hall, Elias I. Traboulsi, Krzysztof Palczewski, Zheng-Rong Lu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 823-835 (2022)
Stargardt disease (STGD) is the most common form of inherited retinal genetic disorders and is often caused by mutations in ABCA4. Gene therapy has the promise to effectively treat monogenic retinal disorders. However, clinically approved adeno-assoc
Externí odkaz:
https://doaj.org/article/cb04137658994b97a05895718c16a714
Autor:
Guanping Yu, Song Qi Gao, Marcin Golczak, Zheng-Rong Lu, Krzysztof Palczewski, Akiko Maeda, Anthony Puntel
Publikováno v:
Biomaterials. 44:103-110
Retinal degeneration impairs the vision of millions in all age groups worldwide. Increasing evidence suggests that the etiology of many retinal degenerative diseases is associated with impairment in biochemical reactions involved in the visual cycle,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91cdf24f09de0bed6af83d6c943f5d35
https://doi.org/10.1016/j.biomaterials.2014.12.019
https://doi.org/10.1016/j.biomaterials.2014.12.019
Autor:
Song Qi Gao, Zheng-Rong Lu, Nadia Ayat, Krzysztof Palczewski, Marcin Golczak, Akiko Maeda, Guanping Yu, Xueming Wu
Publikováno v:
Biomacromolecules
A polyethylene glycol (PEG) retinylamine (Ret-NH2) conjugate PEG-GFL-NH-Ret with a glycine-phenylalanine-leucine (GFL) spacer was synthesized for controlled oral delivery of Ret-NH2 to treat retinal degenerative diseases, including Stargardt disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91278750525ff91c154d30b60b537562
https://doi.org/10.1021/bm501352s
https://doi.org/10.1021/bm501352s
Autor:
Da Sun, Schur, Rebecca M., Sears, Avery E., Song-Qi Gao, Wenyu Sun, Naderi, Amirreza, Kern, Timothy, Palczewski, Krzysztof, Zheng-Rong Lu
Publikováno v:
ACS Applied Bio Materials; 5/18/2020, Vol. 3 Issue 5, p3078-3086, 9p
Publikováno v:
Pharmaceutical Research. 25:218-226
To quantitate and predict colon-specific 9-aminocamptothecin (9-AC) release from the N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-9-AC conjugate and its absorption behavior after oral administration in rats.Drug distribution in the gastrointest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0396af1e719a471df3cbee781de79b
https://doi.org/10.1007/s11095-007-9465-3
https://doi.org/10.1007/s11095-007-9465-3
Publikováno v:
Journal of Controlled Release. 117:179-185
A water soluble N -(2-hydroxypropyl)methacrylamide (HPMA) copolymer–9-aminocamptothecin (9-AC) conjugate was designed for oral colon-specific drug delivery in the treatment of colon cancer. Comparative studies between the polymer conjugate and free
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d51587e4681b0a25d5d6fdd7459a9078
https://doi.org/10.1016/j.jconrel.2006.10.024
https://doi.org/10.1016/j.jconrel.2006.10.024
Publikováno v:
Journal of Controlled Release. 110:323-331
N-(2-Hydroxypropyl)methacrylamide (HPMA) copolymer–9-aminocamptothecin (9-AC) conjugate for oral colon-specific drug delivery was designed, synthesized, and characterized. The drug, 9-AC, was attached to the polymer carrier via a spacer containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49fc04da8632413c9446d480f9ec8699
https://doi.org/10.1016/j.jconrel.2005.10.004
https://doi.org/10.1016/j.jconrel.2005.10.004
Publikováno v:
Bioconjugate chemistry. 11(1)
An amino group containing cyclosporin A (CsA) derivative has been synthesized and conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer via an aromatic azo bond, which can be specifically cleaved by azoreductase activity in colon to releas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f58068edb1088c09270a4967b111ae0
https://pubmed.ncbi.nlm.nih.gov/10639078
https://pubmed.ncbi.nlm.nih.gov/10639078
Publikováno v:
Investigative Opthalmology & Visual Science. 53:6314
To design and develop a drug-delivery system containing a combination of poly(D,L-lactide-co-glycolide) (PLGA) microparticles and alginate hydrogel for sustained release of retinoids to treat retinal blinding diseases that result from an inadequate s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f8b811dfe1a40859927a17f37e7731
https://doi.org/10.1167/iovs.12-10279
https://doi.org/10.1167/iovs.12-10279
Publikováno v:
Pharmaceutical Research; Jan2008, Vol. 25 Issue 1, p218-226, 9p