Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Song-Kun Shyue"'
Autor:
Chin-Kai Chuang, Su-Fen Chen, Yu-Hsiu Su, Wei-Hsin Chen, Wei-Ming Lin, I-Ching Wang, Song-Kun Shyue
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6427 (2023)
Three waves of hematopoiesis occur in the mouse embryo. The primitive hematopoiesis appears as blood islands in the extra embryonic yolk sac at E7.5. The extra embryonic pro-definitive hematopoiesis launches in late E8 and the embryonic definitive on
Externí odkaz:
https://doaj.org/article/aeb8d131e3774885b5eb3bda11f59033
Autor:
Chun-Hu Wu, Chien-Cheng Chen, Tai-Ho Hung, Yen-Chieh Chuang, Min Chao, Song-Kun Shyue, Szu-Fu Chen
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-16 (2019)
Abstract Background Intracerebral hemorrhage (ICH) induces a complex sequence of apoptotic cascades that contribute to secondary neuronal damage. Tropomyosin-related kinase receptor B (TrkB) signaling plays a crucial role in promoting neuronal surviv
Externí odkaz:
https://doaj.org/article/3f8bed877dc346c29c1e4118f2b4a603
Publikováno v:
Cellular Physiology and Biochemistry, Vol 50, Iss 4, Pp 1216-1229 (2018)
Background/Aims: Olanzapine, an atypical antipsychotic drug, has therapeutic effects for schizophrenia. However, clinical reports indicate that patients taking atypical antipsychotic drugs are at high risk of metabolic syndrome with unclear mechanism
Externí odkaz:
https://doaj.org/article/cd4970e1baab4b63aceb71ab2d7185ce
Autor:
Chun-Hu Wu, Song-Kun Shyue, Tai-Ho Hung, Shin Wen, Chao-Chang Lin, Che-Feng Chang, Szu-Fu Chen
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-21 (2017)
Abstract Background Inflammatory responses significantly contribute to neuronal damage and poor functional outcomes following intracerebral hemorrhage (ICH). Soluble epoxide hydrolase (sEH) is known to induce neuroinflammatory responses via degradati
Externí odkaz:
https://doaj.org/article/65986df5c69e4117887c43ce052faf0e
Autor:
May-Jywan Tsai, Chi-Ting Huang, Yong-San Huang, Ching-Feng Weng, Song-Kun Shyue, Ming-Chao Huang, Dann-Ying Liou, Yan-Ru Lin, Chu-Hsun Cheng, Huai-Sheng Kuo, Yilo Lin, Meng-Jen Lee, Wen-Hung Huang, Wen-Cheng Huang, Henrich Cheng
Publikováno v:
Journal of Biomedical Science, Vol 24, Iss 1, Pp 1-14 (2017)
Abstract Background Olfactory ensheathing cells (OEC), specialized glia that ensheathe bundles of olfactory nerves, have been reported as a favorable substrate for axonal regeneration. Grafting OEC to injured spinal cord appears to facilitate axonal
Externí odkaz:
https://doaj.org/article/a502df3407574de7be561197821f52f1
Autor:
Yi-Ting Lin, Shu-Man Liang, Ya-Ju Wu, Yi-Ju Wu, Yi-Jhu Lu, Yee-Jee Jan, Bor-Sheng Ko, Yung-Jen Chuang, Song-Kun Shyue, Cheng-Chin Kuo, Jun-Yang Liou
Publikováno v:
Cancers, Vol 11, Iss 2, p 168 (2019)
Focal adhesion kinase (FAK) plays an important role in vascular development, including the regulation of endothelial cell (EC) adhesion, migration, proliferation, and survival. 3’-deoxyadenosine (cordycepin) is known to suppress FAK expression, cel
Externí odkaz:
https://doaj.org/article/27dd0830cc134ddbb65932b66b80be71
Autor:
Chiao‐Po Hsu, Jin‐Feng Zhao, Shing‐Jong Lin, Song‐Kun Shyue, Bei‐Chia Guo, Tse‐Min Lu, Tzong‐Shyuan Lee
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 4 (2016)
BackgroundAsymmetric dimethylarginine (ADMA), an endogenous inhibitor of endothelial nitric oxide synthase (eNOS), is considered a risk factor for the pathogenesis of cardiovascular diseases. Simvastatin, a lipid‐lowering drug with other pleiotropi
Externí odkaz:
https://doaj.org/article/451342f0bc1840778360320009f2de60
Autor:
Jin-Feng Zhao, Li-Chieh Ching, Yu Ru Kou, Shing-Jong Lin, Jeng Wei, Song-Kun Shyue, Tzong-Shyuan Lee
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
The transient receptor potential vanilloid type 1 (TRPV1) is crucial in the pathogenesis of atherosclerosis; yet its role and underlying mechanism in the formation of macrophage foam cells remain unclear. Here, we show increased TRPV1 expression in t
Externí odkaz:
https://doaj.org/article/a3d1c286353548bcb715325c38de65f1
Autor:
Chih‐Feng Lien, Chin‐Sheng Lin, Song‐Kun Shyue, Po‐Shiuan Hsieh, Sy‐Jou Chen, Yi‐Tan Lin, Shu Chien, Min‐Chien Tsai
Publikováno v:
British Journal of Pharmacology.
Autor:
Pei-Chun Chou, Chih-Min Liu, Ching-Hui Weng, Kai-Chien Yang, Mei-Ling Cheng, Yuh-Charn Lin, Ruey-Bing Yang, Bai-Chuang Shyu, Song-Kun Shyue, Jin-Dian Liu, Shih-Pin Chen, Michael Hsiao, Yu-Feng Hu
Publikováno v:
Circulation research. 131(1)
Background: The sino atrial node (SAN) is characterized by the microenvironment of pacemaker cardiomyocytes (PCs) encased with fibroblasts. An altered microenvironment leads to rhythm failure. Operable cell or tissue models are either generally lacki