Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Song-Chu Lee"'
Autor:
Robert Schwarcz, Song-Chu Lee
Publikováno v:
Neuroscience Letters. 304:185-188
Peripheral administration of L-4-chlorokynurenine (4-Cl-KYN), which is enzymatically converted in astrocytes to form the glycine(B) receptor antagonist 7-chlorokynurenic acid (7-Cl-KYNA), has been shown to provide neuroprotection against excitotoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3751b23bf0e05a6444045335d0eab2
https://doi.org/10.1016/s0304-3940(01)01791-8
https://doi.org/10.1016/s0304-3940(01)01791-8
Publikováno v:
Experimental neurology. 177(1)
Blockade of the strychnine-insensitive glycine site of the NMDA receptor is considered an attractive strategy for the development of novel neuroprotective and anticonvulsive agents. 7-Cl-kynurenic acid (7-Cl-KYNA) is a potent, selective antagonist of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1eedbe092b9fe48bf36bd6b2009059
https://pubmed.ncbi.nlm.nih.gov/12429224
https://pubmed.ncbi.nlm.nih.gov/12429224
Publikováno v:
European journal of pharmacology. 390(3)
The synthetic compound 4-chlorokynurenine has been shown to be enzymatically transaminated to the selective glycine(B) receptor antagonist 7-chlorokynurenate. Since 4-chlorokynurenine, in contrast to 7-chlorokynurenate, readily penetrates the blood-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8492596cc2da88ef6ffb935ee0e108e0
https://pubmed.ncbi.nlm.nih.gov/10708733
https://pubmed.ncbi.nlm.nih.gov/10708733