Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Song F. Lee"'
Autor:
Niluni M. Wijesundara, Song F. Lee, David N. Langelaan, Abir Lefsay, H.P. Vasantha Rupasinghe
Publikováno v:
Phytomedicine Plus, Vol 4, Iss 3, Pp 100614- (2024)
Background: Phospholipids are significant constituents of bacterial membranes. Bacteria can alter their cytoplasmic membrane fatty acid composition in response to changing environmental stress conditions. Carvacrol, a mono-terpenoid phenol, has excel
Externí odkaz:
https://doaj.org/article/631843ebb3234a759a7c45c4687a7d65
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Streptococcus pyogenes is an important human pathogen worldwide. The identification of natural antibacterial phytochemicals has renewed interest due to the current scarcity of antibiotic development. Carvacrol is a monoterpenoid found in her
Externí odkaz:
https://doaj.org/article/cd082443a5264f24a2524aa2210ff2cb
Autor:
Niluni M. Wijesundara, Song F. Lee, Zhenyu Cheng, Ross Davidson, David N. Langelaan, H. P. Vasantha Rupasinghe
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 1992 (2022)
Background: Carvacrol, a mono-terpenoid phenol found in herbs, such as oregano and thyme, has excellent antibacterial properties against Streptococcus pyogenes. However, its mechanism of bactericidal activity on S. pyogenes has not been elucidated. O
Externí odkaz:
https://doaj.org/article/09a6ec1cf61148eb90bb17a0cb0e63d1
Publikováno v:
Nutrients, Vol 14, Iss 3, p 503 (2022)
Pharyngitis is an inflammation of the pharynx caused by viral, bacterial, or non-infectious factors. In the present study, the anti-inflammatory efficacy of carvacrol was assessed using an in vitro model of streptococcal pharyngitis using human tonsi
Externí odkaz:
https://doaj.org/article/16f3dc2142d648c6b1bce7d996e34a75
Publikováno v:
Microbial pathogenesis. 169
Streptococcus pyogenes is a leading cause of chronic and acute infections, including streptococcus pharyngitis. Biofilm formation by S. pyogenes can cause tolerance against antibiotics. Although penicillin remains the first choice of antibiotic for S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b4181ff836ff7d63fba8140176aa4f
https://pubmed.ncbi.nlm.nih.gov/35863588
https://pubmed.ncbi.nlm.nih.gov/35863588
Publikováno v:
J Bacteriol
Mechanisms of disulfide bond formation in the human pathogen Streptococcus pyogenes are currently unknown. To date, no disulfide bond-forming thiol-disulfide oxidoreductase (TDOR) has been described and at least one disulfide bonded protein is known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2facc110895c6e8ebd73b396f412492
https://europepmc.org/articles/PMC8351626/
https://europepmc.org/articles/PMC8351626/
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Streptococcus pyogenes is an important human pathogen worldwide. The identification of natural antibacterial phytochemicals has renewed interest due to the current scarcity of antibiotic development. Carvacrol is a monoterpenoid found in herbs. We ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5c06e44582e316ede69a373a7b7f47
https://pubmed.ncbi.nlm.nih.gov/33452275
https://pubmed.ncbi.nlm.nih.gov/33452275
Autor:
Naif Jalal, Song F. Lee
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229375 (2020)
PLoS ONE
PLoS ONE
The ability of Streptococcus gordonii to cope with oxidative stress is important for survival and persistence in dental plaque. In this study, we used mutational, phenotypic, and biochemical approaches to characterize the role of a methionine sulfoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4777a731c3552ece2753652263ca589a
https://doaj.org/article/06053fb2f13447eda79ed8a1c3415bf8
https://doaj.org/article/06053fb2f13447eda79ed8a1c3415bf8
Publikováno v:
Journal of bacteriology. 201(10)
We previously identified a novel thiol-disulfide oxidoreductase, SdbA, in Streptococcus gordonii that formed disulfide bonds in substrate proteins and played a role in multiple phenotypes. In this study, we used mutational, phenotypic, and biochemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e72448475d95ba5d52e5d8f1a3f9f8
https://pubmed.ncbi.nlm.nih.gov/30804044
https://pubmed.ncbi.nlm.nih.gov/30804044
Publikováno v:
Trends in Microbiology. 24:902-915
Extracytoplasmic thiol-disulfide oxidoreductases (TDORs) catalyze the oxidation, reduction, and isomerization of protein disulfide bonds. Although these processes have been characterized in Gram-negative bacteria, the majority of Gram-positive TDORs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4406d30fd25cc2e94f263e049b4caf60
https://doi.org/10.1016/j.tim.2016.06.010
https://doi.org/10.1016/j.tim.2016.06.010