Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sonei Sou"'
Autor:
Hiroyasu Takahashi, Mikiko Sodeoka, Ryu Yamasaki, Satoshi Mayumi, Shizuo Kadoya, Yuichi Hashimoto, Sonei Sou
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 10:1081-1084
Novel alpha-glucosidase inhibitors with a tetrachlorophthalimide skeleton were prepared and their structure-activity relationships were analyzed. Among them, N-phenyl-4,5,6,7-tetrachlorophthalimide (CPOP: 2) and N-(4-phenylbutyl)-4,5,6,7-tetrachlorop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b4744abc5acf0ee9a49ed9baff77e7
https://doi.org/10.1016/s0960-894x(00)00161-x
https://doi.org/10.1016/s0960-894x(00)00161-x
Autor:
Yuichi Hashimoto, Yasuyuki Endo, Ryu Yamasaki, Hiroyasu Takahashi, Hiroyuki Kagechika, Sonei Sou
Publikováno v:
Chemicalpharmaceutical bulletin. 49(6)
Previous studies of α-glucosidase inhibitors derived from thalidomide revealed that 4, 5, 6, 7-tetrachloro-N-alkylphthalimide derivatives are superior lead compounds. Structure-activity relationship studies indicated that a hydrophobic group at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6be13a7f40fdafa522d133c617025d7
https://pubmed.ncbi.nlm.nih.gov/11411542
https://pubmed.ncbi.nlm.nih.gov/11411542
Publikováno v:
ChemInform. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::148927894095cd8f106226abafd0bb13
https://doi.org/10.1002/chin.200111245
https://doi.org/10.1002/chin.200111245
Publikováno v:
Chemicalpharmaceutical bulletin. 48(10)
Alpha-glucosidase inhibitors with a phthalimide skeleton were prepared. Structure-activity relationship studies indicated a critical role for the hydrophobicity of the substituent at the nitrogen atom of the phthalimide skeleton. Introduction of elec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2f2842af767d0a303f85b0877e6661
https://pubmed.ncbi.nlm.nih.gov/11045457
https://pubmed.ncbi.nlm.nih.gov/11045457