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of 8
pro vyhledávání: '"Sonali Bahl"'
Autor:
Sonali Bahl, Hongbo Ling, Nuwan P. N. Acharige, Irene Santos-Barriopedro, Mary Kay H. Pflum, Edward Seto
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-17 (2021)
Abstract HDAC1 is the prototypical human histone deacetylase (HDAC) enzyme responsible for catalyzing the removal of acetyl group from lysine residues on many substrate proteins. By deacetylating histones and non-histone proteins, HDAC1 has a profoun
Externí odkaz:
https://doaj.org/article/3bc10b248f614d199456b5bb1c309538
Autor:
Paula Restrepo, Mercedeh Movassagh, Nawaf Alomran, Christian Miller, Muzi Li, Chris Trenkov, Yulian Manchev, Sonali Bahl, Stephanie Warnken, Liam Spurr, Tatiyana Apanasovich, Keith Crandall, Nathan Edwards, Anelia Horvath
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Asymmetric allele content in the transcriptome can be indicative of functional and selective features of the underlying genetic variants. Yet, imbalanced alleles, especially from diploid genome regions, are poorly explored in cancer. Here we
Externí odkaz:
https://doaj.org/article/de12aae9e1cb49908e4868f2314b57c1
Publikováno v:
Genes & Cancer. 10:119-133
Temozolomide (TMZ) is an alkylating agent chemotherapy drug used as a first-line treatment for glioblastoma multiforme (GBM). O6-methyl-guanine DNA methyltransferase (MGMT) repairs DNA damage induced by TMZ; hence, elevated MGMT levels usually correl
Autor:
Nuwan P. N. Acharige, Mary Kay H. Pflum, Hongbo Ling, Edward Seto, Irene Santos-Barriopedro, Sonali Bahl
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 5, Pp 1-17 (2021)
Cell Death and Disease, Vol 12, Iss 5, Pp 1-17 (2021)
HDAC1 is the prototypical human histone deacetylase (HDAC) enzyme responsible for catalyzing the removal of acetyl group from lysine residues on many substrate proteins. By deacetylating histones and non-histone proteins, HDAC1 has a profound effect
Autor:
Sonali Bahl, Edward Seto
Publikováno v:
Cell Mol Life Sci
Histone deacetylases (HDACs) are conserved enzymes that regulate many cellular processes by catalyzing the removal of acetyl groups from lysine residues on histones and non-histone proteins. As appropriate for proteins that occupy such an essential b
Publikováno v:
Genes & Cancer
Temozolomide (TMZ) is an alkylating agent chemotherapy drug used as a first-line treatment for glioblastoma multiforme (GBM). O6-methyl-guanine DNA methyltransferase (MGMT) repairs DNA damage induced by TMZ; hence, elevated MGMT levels usually correl
Autor:
Nawaf Alomran, Mercedeh Movassagh, Keith A. Crandall, Yulian Manchev, Tatiyana V. Apanasovich, Muzi Li, Paula Restrepo, Christian Miller, Sonali Bahl, Anelia Horvath, Stephanie Warnken, Nathan Edwards, Chris Trenkov, Liam F. Spurr
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports
Asymmetric allele content in the transcriptome can be indicative of functional and selective features of the underlying genetic variants. Yet, imbalanced alleles, especially from diploid genome regions, are poorly explored in cancer. Here we systemat
Autor:
Prakriti Mudvari, Cem Dede, Nawaf Alomran, Sonali Bahl, Anelia Horvath, Merve Dede, Mercedeh Movassagh, Muzi Li, Kamran Kowsari, Edmund Cauley, Paula Restrepo, Krasimira Tsaneva-Atanasova, Wesley Waterhouse, Nathan Edwards
Publikováno v:
Nucleic Acids Research
We introduce RNA2DNAlign, a computational framework for quantitative assessment of allele counts across paired RNA and DNA sequencing datasets. RNA2DNAlign is based on quantitation of the relative abundance of variant and reference read counts, follo