Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sonali, Nashine"'
Autor:
Kevin Schneider, Marilyn Chwa, Shari R. Atilano, Sonali Nashine, Nitin Udar, David S. Boyer, S. Michal Jazwinski, Michael V. Miceli, Anthony B. Nesburn, Baruch D. Kuppermann, M. Cristina Kenney
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 10, Pp 675-689 (2022)
Abstract Activation of the Simulator of Interferon Genes (STING) system by mitochondrial (mt) DNA can upregulate type 1 interferon genes and enhance immune responses to combat bacterial and viral infections. In cancers, the tumor‐derived DNA activa
Externí odkaz:
https://doaj.org/article/09bf357e9bfd42d796eda35f47c0bc9b
Autor:
Ashish U Sapkal, Sonali Nashine, Saffar Mansoor, Vishal R Sharma, Claudio A Ramirez, Rafael Z Migon, Navin K Gupta, Marilyn Chwa, Baruch D Kuppermann, Cristina Kenney
Publikováno v:
Journal of Ophthalmic & Vision Research, Vol 13, Iss 4, Pp 419-425 (2018)
Purpose: The aim of this study was to examine the effect of 17β-estradiol on Benzo(e)pyrene [B(e)P]-induced toxicity in ARPE-19 cells. Methods: We pretreated ARPE-19 cells with 20 nM and 40 nM 17β-estradiol for 6 hours, followed by addition of 300
Externí odkaz:
https://doaj.org/article/06a440388809425c9a4d812276df9c44
Autor:
Sonali Nashine
Publikováno v:
Cells, Vol 10, Iss 9, p 2483 (2021)
Aging contributes to the risk of development of ocular diseases including, but not limited to, Age-related Macular Degeneration (AMD) that is a leading cause of blindness in the United States as well as worldwide. Retinal aging, that contributes to A
Externí odkaz:
https://doaj.org/article/636d398d3522491db3dadb48cd27bd71
Autor:
Kevin Schneider, Marilyn Chwa, Shari R. Atilano, Sonali Nashine, Nitin Udar, David S. Boyer, S. Michal Jazwinski, Michael V. Miceli, Anthony B. Nesburn, Baruch D. Kuppermann, M. Cristina Kenney
Publikováno v:
FASEB BioAdvances. 4:675-689
Activation of the Simulator of Interferon Genes (STING) system by mitochondrial (mt) DNA can upregulate type 1 interferon genes and enhance immune responses to combat bacterial and viral infections. In cancers, the tumor-derived DNA activates STING l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c829d9869ab3cff6228175640c73501d
https://doi.org/10.1096/fba.2019-00044
https://doi.org/10.1096/fba.2019-00044
Autor:
Mohamed A. Hamid, M. Tarek Moustafa, Sonali Nashine, Rodrigo Donato Costa, Kevin Schneider, Shari R. Atilano, Baruch D. Kuppermann, M. Cristina Kenney
Publikováno v:
Cells, Vol 10, Iss 4, p 878 (2021)
Our study assesses the effects of anti-VEGF (Vascular Endothelial Growth Factor) drugs and Trichostatin A (TSA), an inhibitor of histone deacetylase (HDAC) activity, on cultured ARPE-19 (Adult Retinal Pigment Epithelial-19) cells that are immortalize
Externí odkaz:
https://doaj.org/article/23d26deb6be246fb8b26d8f16a7fa95d
Autor:
Sonali Nashine, M. Cristina Kenney
Publikováno v:
Cells, Vol 9, Iss 5, p 1102 (2020)
Substantive evidence demonstrates the contribution of mitochondrial dysfunction in the etiology and pathogenesis of Age-related Macular Degeneration (AMD). Recently, extensive characterization of Mitochondrial-Derived Peptides (MDPs) has revealed the
Externí odkaz:
https://doaj.org/article/fcc8b07b306e48d4b33c5980cba4c3da
Publikováno v:
Nutrients, Vol 12, Iss 1, p 159 (2020)
Resveratrol is a phytoalexin, stilbenoid compound with antioxidant properties attributable to its bioactive trans-resveratrol content. This study characterized the effects of over-the-counter (OTC) resveratrol nutritional supplements and a HPLC-purif
Externí odkaz:
https://doaj.org/article/fed973b31b2447ba9eab758f95bc06b3
Publikováno v:
Aging, vol 14, iss 10
Inflammation plays a crucial role in the etiology and pathogenesis of AMD (Age-related Macular Degeneration). Humanin G (HNG) is a Mitochondrial Derived Peptide (MDP) that is cytoprotective in AMD and can protect against mitochondrial and cellular st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d50357f6ee9f710d5f1912e7b4fc8cb
https://escholarship.org/uc/item/40b2x2qp
https://escholarship.org/uc/item/40b2x2qp
Autor:
Sonali Nashine, Marilyn Chwa, Mina Kazemian, Kunal Thaker, Stephanie Lu, Anthony Nesburn, Baruch D Kuppermann, M Cristina Kenney
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0159828 (2016)
Variations in mitochondrial DNA (mtDNA) and abnormalities in the complement pathways have been implicated in the pathogenesis of age-related macular degeneration (AMD). This study was designed to determine the effects of mtDNA from AMD subjects on th
Externí odkaz:
https://doaj.org/article/bad2fa3de45e403398fddacde1584803
Autor:
M. Cristina Kenney, Sonali Nashine
Publikováno v:
Aging. 12:9031-9040
Citicoline is the exogenous form of the nootropic, Cytidine 5'-diphosphate-choline that exerts its neuroprotective effects in the brain as well as in the eye. The current study characterized the cytoprotective effects of purified Citicoline in transm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65988ed3bbc799fb0aab63806b1983ab
https://doi.org/10.18632/aging.103164
https://doi.org/10.18632/aging.103164