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pro vyhledávání: '"Sonald Duclair"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
HIV-1 aspartyl protease (PR) plays a key role in virion morphogenesis, underscoring the effectiveness of protease inhibitors (PI). Despite their utility, side effects and drug-resistance remains a problem. We report the development of RNA aptamers as
Externí odkaz:
https://doaj.org/article/d9f44add0cd4494abe87901ad6b04c47
Autor:
Sonald Duclair, Vinayaka R. Prasad, Siddhartha A. K. Datta, Alan Rein, Dhivya Ramalingam, Andrew D. Ellington
Publikováno v:
Journal of Virology. 85:305-314
Gag orchestrates the assembly and release of human immunodeficiency virus type 1 (HIV-1) particles. We explored here the potential of anti-Gag RNA aptamers to inhibit HIV-1 replication. In vitro , RNA aptamers raised against an HIV-1 Gag protein, lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e6217c353495ffc74f5f008bc97bc7
https://doi.org/10.1128/jvi.02626-09
https://doi.org/10.1128/jvi.02626-09
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
HIV-1 aspartyl protease (PR) plays a key role in virion morphogenesis, underscoring the effectiveness of protease inhibitors (PI). Despite their utility, side effects and drug-resistance remains a problem. We report the development of RNA aptamers as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6678dba3d3ce403da158ef77548251f7
https://doi.org/10.1038/mtna.2015.1
https://doi.org/10.1038/mtna.2015.1