Zobrazeno 1 - 10 of 55 pro vyhledávání: '"Sonal dubey"'
1
Akademický článek
Comparison of in-silico and in-vitro studies of benzimidazoleoxothiazolidine derivatives as m. Tubcerculosis transcriptor inhibitors
Autor: Sonal dubey, Sakshi Bhardwaj, Prabitha Prabhakaran, Subhankar Parboth Mandal, Ekta Singh
Publikováno v: German Journal of Pharmaceuticals and Biomaterials, Vol 2, Iss 2, Pp 20-29 (2023)
Novel N-(4-alkyl-4-oxo-1,3-thiazolidin-3-yl)-2-(5-nitro-1H-benzimidazole-1-yl)acetamide derivatives were evaluated as M. tuberculosis transcription inhibitors using protein 3Q3S, by performing molecular docking and molecular dynamics studies. Twelve
Externí odkaz: https://doaj.org/article/cf9c7c46dd3245d9b3949052bd1193cc
Zobrazit plný text záznamu
2
Akademický článek
Computational investigation of quinazoline derivatives as Keap1 inhibitors for Alzheimer's disease
Autor: Sharmila Gote, Shankar Thapa, Sonal Dubey, Shachindra L. Nargund, Mahalakshmi Suresha Biradar
Publikováno v: Informatics in Medicine Unlocked, Vol 41, Iss , Pp 101334- (2023)
The Keap1-Nrf2-ARE pathway is crucial in the antioxidant defense mechanism. The Keap1-Nrf2-ARE pathway has become an important target for the development of potent therapeutic agents for numerous diseases. Keap1-Nrf2 protein inhibitors are electrophi
Externí odkaz: https://doaj.org/article/0af493804aff4e3980fff1b1333004d5
Zobrazit plný text záznamu
5
Synthesis of some Novel Benzimidazole-Oxothiazolidine Derivatives as Anti-Tubercular agents: Conventional Vs Microwave Assisted Approach
Autor: Sonal Dubey, Sakshi Bhardwaj
Publikováno v: Research Journal of Science and Technology. :199-207
N-(4-alkyl-4-oxo-1,3-thiazolidin-3-yl)-2-(5-nitro-1H-benzimidazole-1-yl)acetamide derivatives were designed and synthesis. Twelve novel derivatives were synthesized using conventional approach and Microwave-assisted synthesis. Herein we report the co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72df3c3c81978d867865bc93304d79ea
https://doi.org/10.52711/2349-2988.2022.00033
Zobrazit plný text záznamu
6
In silico Prediction of Pyrazoline Derivatives as Antimalarial agents
Autor: Sonal Dubey, Sakshi Bhardwaj, Prabitha Parbhakaran, Ekta Singh
Publikováno v: Asian Journal of Pharmaceutical Research. :119-124
Malaria is one of the toughest health and development challenges faced by tropical countries. The resistance of malarial parasite to available drugs and currently used chemotherapy made its emergence for development of new drugs. Pyrazoline derivativ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2273b9c5c20e3fbafd6ff398dec7b13c
https://doi.org/10.52711/2231-5691.2022.00018
Zobrazit plný text záznamu
7
Qsar and Docking Studies of Some Novel Piperine Analogues as Monoamine Oxidase Inhibitors
Autor: Sakshi Bhardwaj, Sonal Dubey
Publikováno v: Asian Journal of Research in Pharmaceutical Sciences. :115-122
Piperine is an attractive target from natural sources for designing of novel compounds for many pharmacological activities. In present work, series of MAO inhibitors were taken and QSAR models were generated using MLRA. The best model were validated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b27974bc355fb56cc9cda1f4b87667a8
https://doi.org/10.52711/2231-5659.2022.00019
Zobrazit plný text záznamu
9
A study of pyrazolo-benzimidazole derivatives as spleen tyrosine kinase inhibitors: an in-silico approach
Autor: P. Prabitha, Sonal Dubey, Ekta Singh, Sakshi Bhardwaj
Publikováno v: Structural Chemistry. 30:263-272
In an effort to contribute designing of improved anticancer molecules, in-silico prediction data including pharmacophore hypothesis, 3D-QSAR model, and molecular docking studies were performed on 55 compounds collected from literature. Tyrosine kinas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9b2f05155ab8f1e7de3a8a30aaa8542
https://doi.org/10.1007/s11224-018-1189-y
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje