Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sonal P. Sanghani"'
Autor:
E. Gabriela Chiorean, Matthew Burns, Menggang Yu, David T. Hinkle, Jose A. Bufill, Romnee Clark, Higinia R. Cardenes, Nicki Coleman, Bruce W. Robb, Sonal P. Sanghani, Patrick J. Loehrer, Marissa A. Schiel, Colleen Curie, Julia K. Leblanc, Yan Tong
Publikováno v:
Cancer Chemotherapy and Pharmacology. 70:25-32
We designed this study in locally advanced rectal cancer to determine the pathological response, toxicity, and disease-free survival (DFS) with induction capecitabine plus irinotecan followed by capecitabine-based chemoradiotherapy (CRT) and analyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f83796587a0bbecf189a2875051901
https://doi.org/10.1007/s00280-012-1883-1
https://doi.org/10.1007/s00280-012-1883-1
Autor:
Alice Nakatsuka, William F. Bosron, Sonal P. Sanghani, Hidekazu Tsukamoto, Wilhelmina I. Davis, Tommaso Mello, Sharry L. Fears
Publikováno v:
Biochemical and Biophysical Research Communications. 374:460-464
Approximately 80% of the body vitamin A is stored in liver stellate cells with in the lipid droplets as retinyl esters. In low vitamin A status or after liver injury, stellate cells are depleted of the stored retinyl esters by their hydrolysis to ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6de17be3accdd9ec1d4e842a7f699b
https://doi.org/10.1016/j.bbrc.2008.07.024
https://doi.org/10.1016/j.bbrc.2008.07.024
Autor:
Alan M. Mahrenholz, Wilhelmina I. Davis, Sonal P. Sanghani, William F. Bosron, Natividad Dumaual
Publikováno v:
European Journal of Biochemistry. 269:4387-4398
Retinyl esters are a major endogenous storage source of vitamin A in vertebrates and their hydrolysis to retinol is a key step in the regulation of the supply of retinoids to all tissues. Some members of nonspecific carboxylesterase family (EC 3.1.1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40ad1eb86e701fc3d902b6502b81fed1
https://doi.org/10.1046/j.1432-1033.2002.03121.x
https://doi.org/10.1046/j.1432-1033.2002.03121.x
Autor:
Masakiyo Hosokawa, Palmer Taylor, William F. Bosron, Tetsuo Satoh, Bert N. La Du, Sonal P. Sanghani
Publikováno v:
Drug Metabolism and Disposition. 30:488-493
This article reports on a symposium sponsored by the American Society for Pharmacology and Experimental Therapeutics and held at the April 2001 Experimental Biology meeting. Current developments in molecular-based studies into the structure and funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4354e6201a9088630ec22a887159fb1
https://doi.org/10.1124/dmd.30.5.488
https://doi.org/10.1124/dmd.30.5.488
Publikováno v:
Journal of Biological Chemistry. 274:27018-27027
Three cysteines in human recombinant folylpoly-gamma-glutamate synthetase (FPGS) that were reactive with iodoacetamide were located in peptides that were highly conserved across species; the functions of two of these peptides, located in the C-termin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d61a58a2020212bd0e8c52143af16cc
https://doi.org/10.1074/jbc.274.38.27018
https://doi.org/10.1074/jbc.274.38.27018
Autor:
Richard G. Moran, Sonal P. Sanghani
Publikováno v:
Biochemistry. 36:10506-10516
The binding of the prototypical folate inhibitor of de novo purine synthesis, 5,10-dideazatetrahydrofolate (DDATHF), and its hexaglutamate to recombinant trifunctional mouse glycinamide ribonucleotide formyltransferase (rmGARFT) was studied by equili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b315448b03b49438bf588460880a354
https://doi.org/10.1021/bi970825u
https://doi.org/10.1021/bi970825u
Autor:
Stephanie D. Fitz, Amy D. Dietrich, Pamela E Minick, Philip L. Johnson, William A. Truitt, Sonal P. Sanghani, Lena Brundin, Anantha Shekhar, Andrew Goddard, Lil Träskman-Bendz
Publikováno v:
Nature medicine, vol 16, iss 1
Nature medicine
Nature medicine
Introductory paragraph Panic disorder is a severe anxiety disorder with recurrent, debilitating panic attacks. In subjects with panic disorder there is evidence of decreased central GABAergic activity as well as marked increases in autonomic and resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033edf488593f3857429bc4f56a1368d
https://escholarship.org/uc/item/00x1k8w8
https://escholarship.org/uc/item/00x1k8w8
Autor:
Reuben Kapur, Feng Chun Yang, Mark G. Goebl, Sonal P. Sanghani, Jeanette N. McClintick, Eric A. Benson, D. Wade Clapp, Maureen A. Harrington
Publikováno v:
Experimental hematology. 38(2)
Objective Emerging work has revealed an integral role of the tumor necrosis factor–α (TNF-α) nuclear factor (NF)-κB pathway in the regulation of hematopoiesis. TNF-α inhibition of hematopoietic stem/progenitor cell growth involves type I TNF-α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fac64df4f0c1375f877e8b0807403f
https://pubmed.ncbi.nlm.nih.gov/19941935
https://pubmed.ncbi.nlm.nih.gov/19941935
Autor:
Lanmin Zhai, Yaoping Tang, Scheri Lyn Green, Wilhelmina I. Davis, Emil Martin, Sharry L. Fears, Paresh C. Sanghani, Sonal P. Sanghani, Nathan S. Bryan
Publikováno v:
The Journal of biological chemistry. 284(36)
S-Nitrosoglutathione reductase (GSNOR) is an alcohol dehydrogenase involved in the regulation of S-nitrosothiols (SNOs) in vivo. Knock-out studies in mice have shown that GSNOR regulates the smooth muscle tone in airways and the function of beta-adre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197048b9aa5a3ca26e1f47996635f666
https://pubmed.ncbi.nlm.nih.gov/19596685
https://pubmed.ncbi.nlm.nih.gov/19596685
Publikováno v:
Protein and peptide letters. 16(10)
Carboxylesterases belong to Phase I group of drug metabolizing enzymes. They hydrolyze a variety of drug esters, amides, carbamates and similar structures. There are five ‘ carboxylesterase ’ genes listed in the Human Genome Organization database
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b42a5eaee2f2a2ea2da7a259c25a0c6
https://pubmed.ncbi.nlm.nih.gov/19508181
https://pubmed.ncbi.nlm.nih.gov/19508181